The Voodoo Music Experience is down one major act after Green Day announced they have pulled out of the event.
"Canceling shows is something we rarely do," said drummer Tré Cool in a statement released by the group. "We never let our fans down, and we are grateful for all of you being understanding during this time."
The New Orleans festival announced the band as headliner in May and they were scheduled to perform on October 27.
It has been a rough couple of months for the group following the onstage meltdown of frontman Billie Joe Armstrong during the iHeartRadio Music Festival.
His profanity laden outburst came after the band was forced to end their set 20 minutes early due to a scheduling conflict with another act. The tantrum ended with Armstrong smashing his guitar on the festival stage.
The group postponed several appearances following the tirade and Armstrong checked himself into a rehab clinic for substance abuse.
Green Day bass player Mike Dirnt told BBC 1 that the band made the decision to cancel all appearances for the next few weeks out of their duty to "put the life of our friend in front of everything".
The group released their new album "¡Uno!" on September 24, and Dirnt said there was a lot of pressure attached to promoting the project.
"Hindsight is 20/20 ... it was a tremendous undertaking, said Dirnt. "It catches up with you a little bit. We definitely jumped off a moving train."
He is still hopeful the band will be reunited soon as they "get ready for the next phase" which includes the release of "¡Dos!" and "¡Tré!" -- the final two albums in the trilogy. The group will also headline a show at London's Emirates Stadium on June 1, 2013.