I knew right away that something was different. My 74-year-old mother and I had been very close all my life. (She lives with my family.) When her personality started to change, I couldn't understand why. She loved crafts, gardening, singing, piano, anything creative, but all of a sudden she wasn't interested in her hobbies. She just wanted to sit in her chair and watch TV. We started to argue. It reminded me of when I was a teenager 25 years earlier, how we would squabble over stupid things. Now she would get angry at the littlest thing and slam her bedroom door in my face.