The winning Powerball numbers for September 18 are 7, 10, 22, 32, 35 and the Powerball number is 19.
According to the Powerball website, there was one winning ticket sold in South Carolina for the $399,400,000 grand prize.
Wednesday's jackpot was the fourth-largest prize in the lottery's history and the fifth-largest of any U.S. lottery, the Multi-State Lottery Association said.
Powerball is played in 43 states, Washington and the U.S. Virgin Islands.
The odds of winning the Powerball lottery jackpot are 1 in 175,223,510.