09/10/2014 04:21 pm ET Updated Sep 10, 2014

Jennifer Aniston Describes Letting Herself Go For Her Least Glamorous Role Yet

George Pimentel via Getty Images

This weekend, our Toronto Film Festival correspondent Richard Lawson reported back to us about the actors up north who are making waves with their impressive dramatic resurgences—Al Pacino, Keira Knightley, and Reese Witherspoon among them. And now, it seems, that we have another actress to add to that list—Jennifer Aniston, who received a standing ovation after last night’s premiere of Cake, an indie drama in which the Friends alum plays a woman suffering from chronic pain.

Read more on www.vanityfair.com