“Every birthday ... we would go out to a special lunch, just the two of us,” Arquette, who currently stars in the YouTube Premium comedy, “Sideswiped,” told host Andy Cohen. “That was a very special time, and we always had champagne. I love her so much.”
A transgender actress best known for her roles in “Last Exit to Brooklyn” and “The Wedding Singer,” Alexis died Sept. 11, 2016, at the age of 47 from complications related to HIV/AIDS.
“It’s been really painful for all of us,” she said. “We’re in PTSD.”
To honor their sister, the Arquettes created The Alexis Project, a specialized clinic for LGBTQ youth at Los Angeles County + USC Medical Center.
Elsewhere in the interview, Arquette dished to Cohen about bonding with another LGBTQ icon, Madonna, over “broken hearts [and] relationships” when the two co-starred in the 1985 comedy, “Desperately Seeking Susan.”
“I got a lot of late-night phone calls,” Arquette, who said she attended the Queen of Pop’s Oscars party in March, recalled. “She’d always call me at 3 a.m. when I had a 5 a.m. call.”