Frasier's Bebe Neuwirth Ties the Knot

06/05/2009 05:12 am ET | Updated May 25, 2011

Lilith is off the market. Bebe Neuwirth, best known as the uptight ex-wife of TV's Frasier Crane on Cheers and Frasier, married Chris Calkins, founder of Napa Valley's Destino vineyard.

Neuwirth, 50, and Calkins swapped "I do's" in front of roughly 80 guests at the Players Club in Manhattan's Gramercy Park, with pal Peter Coyote presiding over the Buddhist/Christian ceremony, her rep confirms to PEOPLE.

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