Leonardo DiCaprio: 'No Control What People Think' About 'Shutter Island' (VIDEO)

"Shutter Island" director Martin Scorcese and star Leonardo DiCaprio appear on ABC News' "Nightline" Wednesday night to discuss the film, which premieres Friday.

DiCaprio says that it's out of his and Scorcese's hands whether audiences respond to the film.

"The only one thing I've learned in my career thus far is you have no control what people think," he said. "You only can go in there with the best intentions, give everything you possibly can, try your best to make the best possible movie you can, and then it's like kind of giving birth. You give it out to the world and they either become a juvenile delinquent or the next President of the United States."

Scorcese said that he does care about the audience's reaction, though.

"Oh, of course, you want an audience, want people to like my work, that would be nice," he told McFadden. "Or respond to it. It'd be nice if they do, touch certain chords in an audience. That sort of thing."

WATCH:

The interview airs tonight on "Nightline" at 11:35 ET.