Weight Loss Drug, Contrave, Rejected By FDA

DIET DRUG REJECTED: The Food and Drug Administration has declined to approve an experimental weight loss drug called Contrave, a surprising rejection to what many analysts expected to be the first new diet drug in a decade.

QUESTIONS OF THE HEART: The FDA asked Contrave to conduct an additional study focused on the drug's heart side effects, a long-standing safety issue with weight loss medications.

FUTURE UNCERTAIN: FDA's request sent shares of drugmaker Orexigen Therapeutics tumbling. Orexigen Therapeutic said the company would have to raise additional money to complete the study, which would likely take years to conduct.

Comments

[M Maryama]

10:00 PM on 02/07/2011

i cant log into my google account I quit

[JackHoffman]

07:22 PM on 02/02/2011

Eat less, walk more.

[Linda Matuskey]

01:19 AM on 02/02/2011

I was in a clinical trial with Contrave and lost 63 pounds in 16 months. It was effortless...I can't believe the FDA rejected it. The drugs are not new: naltrexone combined with buproprion.

[OverseasVet]

09:31 AM on 02/02/2011

The drugs are not new and the FDA's pre-approval study request is idiotic and will stop all new studies into obesity drugs. Congratulations on the weight loss. Hope the FDA doesn't take the momentum away from an excellent accomplishment.

[alteredstory]

10:55 AM on 02/02/2011

However, when you combine two chemicals, they produce different effects than if you took them each separately. That's why so many chemical warning labels have a catch-all clause saying they don't know what the impact will be if it's mixed with something else, and why many medications say "don't take with [insert group of chemicals/drugs]"

[M Maryama]

04:39 PM on 02/01/2011

Weight loss is extreme variable for each individual. For those who eat so much that they become type 2 diabetics you might want to see what some of the other type 2 diabetics are go through because their pancreus doesn't produce enough insulin or what type 1 (or insulin dependent) diabetics go through and if you had any rationality you would stop eating so much and enjoy life in other ways. Type 1 and 2 diabetes are hereditary and can sometimes begin at the age of 2 (it used to be in the 7-12 range). As you get older you have to be your own pancreus, sound easy, no way. I feel bad for the parents of type 1 diabetics for many reasons but more so for the child. Message for overeaters: If you are not already diabetic you will become one and suffer the complications which you brought on by yourself, the only sympathy I have for you is that you are an addict, but addicts can take the necessary steps to help their problem. Typical (type 1 or those who don't produce enough insulin) diabetics cannot, they are stuck with it from the day they started developing syptoms, so get yourself help, it's available to you or go see a life in the day of a 10 year old diabetic or a person who has developed complications from diabetes and maybe that will motivate you, Mike Maruyama [e-mail]

www.my.myebookstand.com
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[jonester]

01:50 PM on 02/01/2011

Here's an idea: Get of your butt and workout!