Demi Moore was long considered a celebrity role model for helming a successful blended family with ex-husband Bruce Willis, their three children and current husband Ashton Kutcher.
"I like being what the girls call MOD--'my other Dad,'" said Kutcher.
That all came to an end Thursday when Moore filed for divorce from Kutcher, her husband of six years.
But they're hardly the only celebrity blended family to split. Click through our slideshow to view other high profile families who went from blended to ended.
When Madonna and Guy Ritchie were married in 2000, Madonna's daughter Lourdes (from her previous relationship with personal trainer Carlos Leon) was already in the picture. The couple divorced in 2008.
When Cage and Arquette were married in April 1995, each already had a son from their previous relationships. The couple officially split ways in 2001, after reconciling and filing for divorce multiple times.
Comedian and actor Steve Harvey already had three children (twin daughters named Karli and Brandi, and one son, Broderick Jr.) from his previous marriage when he wed Mary Shackelford. Unfortunately, their marriage didn't last either -- the two separated in 2005, after ten years of marriage and a child together. Harvey married again two years later.
Actress Elizabeth Hurley and businessman Arun Nayar were wed in 2007 with two ceremonies -- a private civil ceremony at a English castle and a lavish and traditional Hindu wedding in Jodphur, India. But their fairytale romance didn't last long -- the couple divorced just four years after their marriage. Hurley already had a son, Damian, from a previous relationship with film producer Steve Bing.
When Britney Spears started dating backup dancer Kevin Federline in 2004, he already had one child from his previous relationship with actress Shar Jackson -- and another one on the way. Spears and Federline were wed later that year and divorced in 2006, citing irreconcilable differences.