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Soda-Cancer Link Suggested By Controversial Report On 4-MI, Cola Dye Byproduct


First Posted: 03/ 6/2012 2:33 pm Updated: 03/ 9/2012 3:47 pm

The Center for Science in the Public Interest (CSPI), a consumer interest group, released a report today linking Coca-Cola, Diet Coke, Pepsi and Diet Pepsi -- the 1st-, 2nd-, 3rd- and 6th- best-selling sodas in the world, respectively -- to a chemical that has been known to cause cancer in lab rats and mice. The report has raised alarm bells, not for the first time, about the risks soda poses to public health -- even though many experts were quick and unequivocal in their denunciation of its findings.

The CSPI argues that the amount of the chemical present in the sodas presents a risk to public health. For that reason, the group has petitioned the FDA to mandate a label on soda containers warning consumers of the risk of cancer.

The chemical, 4-methylimidazole, usually known as 4-MI and sometimes 4-MEI, is a byproduct of the chemical process soda companies use to create the artificial dye that gives the sodas their trademark caramel coloring. Studies linking 4-MI to cancer in mice prompted the state of California to list it as a carcinogen in spring of 2009. It's illegal to sell any food or beverage containing an amount of 4-MI that could increase the risk of cancer by more than 1 case per 100,000 people in California without a warning label. The CSPI alleges that the levels it found in sodas would increase the risk by as much as 4.8 cases per 100,000 people.

Officials from the FDA and the American Beverage Association (ABA) slammed the idea that the chemical poses a risk to consumers.

"Time and again, and even very recently," the ABA wrote in its statement on the report, "leading public health organizations have reaffirmed that caramel coloring, including the trace amounts of 4-MEI found in it, is safe for use in colas and countless other foods."

A Vanderbilt University biochemist told Time's Bryan Walsh that 4-MI would only increase a person's risk of cancer if he or drank 1000 cans of cola per day.

And this also isn't the first time the CSPI has tried to raise awareness about what it perceives as the risks of 4-MI. It did so in a report and petition last February as well. That release did not, however, include test results for individual brands of soda.

Even if the caramel dye isn't as carcinogenic as the CSPI is alleging, there are still plenty of reasons to drink less soda. Sugary soft drinks have already been linked to higher rates of obesity and diabetes. And at the very least, this latest report gives us yet another reason to be nostalgic for Crystal Pepsi.

UPDATE 3/7: NPR reported today that Coca-Cola is tweaking the recipe it uses to make the caramel dye that it uses to color its product to reduce the chance that its soda cans would get a warning label in California. But Coca-Cola spokesperson Ben Sheidler affirmed the safety of the company's product in an email to the Huffington Post. "The 4-MEI levels in our products pose no health or safety risks," he said. "Outside of California, no regulatory agency concerned with protecting the public's health has stated that 4-MEI is a human carcinogen. The caramel color in all of our ingredients has been, is and always will be safe."

UPDATE 3/8: The AP now reports that Pepsi is also rejiggering its dye formula to avoid a warning label in California. Both Pepsi and Coca-Cola, the AP continues, have plans to take the new formula national at some point in the future.

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The Center for Science in the Public Interest (CSPI), a consumer interest group, released a report today linking Coca-Cola, Diet Coke, Pepsi and Diet Pepsi -- the 1st-, 2nd-, 3rd- and 6th- best-sellin...
The Center for Science in the Public Interest (CSPI), a consumer interest group, released a report today linking Coca-Cola, Diet Coke, Pepsi and Diet Pepsi -- the 1st-, 2nd-, 3rd- and 6th- best-sellin...
The Center for Science in the Public Interest (CSPI), a consumer interest group, released a report today linking Coca-Cola, Diet Coke, Pepsi and Diet Pepsi -- the 1st-, 2nd-, 3rd- and 6th- best-sellin...
The Center for Science in the Public Interest (CSPI), a consumer interest group, released a report today linking Coca-Cola, Diet Coke, Pepsi and Diet Pepsi -- the 1st-, 2nd-, 3rd- and 6th- best-sellin...
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HUFFPOST SUPER USER
Django48
The crispy noodle in the vegetarian salad of life
01:59 PM on 03/12/2012
Thank you California.
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HUFFPOST SUPER USER
ttsgw
Atheist and secular humanist
06:18 AM on 03/11/2012
Why schould anyone care if they get cancer from drinking coke, the main reason for drinking it is to enrich the owners and exevutives of the Coca-Cola company. True Americans would rather die than see these guys loose any money.
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HUFFPOST SUPER USER
OriginalName
Moral indignation is jealousy with a halo.
04:40 PM on 03/10/2012
The FDA. Serving the public interest. NOT.
04:06 PM on 03/10/2012
I'm more concerned about the addictive properties of Caffeine, or the very low pH dissolving my teeth, or the artificial sweeteners causing insulin response, or even the plastic inner coating leaching god knows what into the soda. All of these things are potential problems with carbonated beverages that one can get excited about without needing to ban the minute quantities of carcinogen dye in them.

"Flouridation Mandrake!" "It's why I only drink rainwater, and pure grain alcohol."
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HUFFPOST SUPER USER
oldwolf49
Religion is a tool of the evil.
11:19 PM on 03/09/2012
Mexican Coke!!
HUFFPOST SUPER USER
Edogg62
02:26 PM on 03/09/2012
I'm probably "addicted" to diet soda, but anyone who doesn't think ingesting man-made chemicals is hazardous is living in denial. I have no reason to suspect anything different from MY addiction for these beverages. I don't drink alcohol, don't smoke and don't do drugs, so I don't know MUCH about addictions, but I DO know that I will absolutely crave diet soda from time to time. Time to get that monkey off my back...
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YouAreJokingRight
Taking you less seriously than you take yourself.
06:46 PM on 03/09/2012
When you crave a soda, drink 100% juice. Re-train your brain. Juice is full of natural sugars so you'll get the sweet craving satisfied without the chemicals.
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HUFFPOST SUPER USER
sensimilla
Lead with your heart, and your mind will follow...
08:17 PM on 03/12/2012
most 100% juice is bad for you, it slams your blood sugar levels. Now, vegetable/fruit juice with pulp is not a bad thing overall.
03:56 PM on 03/10/2012
I know a thing or two about addiction, and Caffeine is sweet sweet nectar.
I switched to mostly unsweetened tea a while back and my teeth are no more or less stained, but I burp a lot less and don't have to worry about the aspartame or acid... Just the pesticides and heavy metals for me!
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Jay from Ottawa
sovereignty sale, 1.3T OBO
01:44 PM on 03/09/2012
Why not simply avoid 4-MI in the first place ?

Colour is superficial, I couldn't care less if my soda was any other colour.

Once again, corporate America is using Americans like guinea pigs.
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YouAreJokingRight
Taking you less seriously than you take yourself.
06:46 PM on 03/09/2012
Apparently the soda is a very unattractive greenish color without the dye.
03:58 PM on 03/10/2012
Guinea pigs don't have the right endocrine response to be used effectively in chemical trials.
Humans are cheaper.
This user has chosen to opt out of the Badges program
Professor Wagstaff
My micro-bio is a lie
12:58 PM on 03/09/2012
Amazing that they would risk all the bad publicity when they could switch dyes. Just how much cheaper is the carcinogenic 4-methylimidazole than a natural coloring agent?

After all brown is easily obtaining by mixing other colors - ask any finger painting kindergarten kid.
11:20 AM on 03/09/2012
I don't think so....
12:08 AM on 03/09/2012
My buddie told me coca cola at one time had coke ( the drug ) in it. I don't believe it.
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hauruck
Bitten by a radioactive Welshman
12:54 AM on 03/09/2012
It actually did, but that was a VERY long time ago. It's where the "coca" in "Coca Cola" comes from.
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HUFFPOST SUPER USER
Mary Blickhahn
Is this really the best we can do?
10:59 AM on 03/09/2012
It is very true! Coca Cola had cocaine as an ingredient!
03:21 PM on 03/08/2012
I like coke but could they keep everything but the dye.
01:32 PM on 03/08/2012
Why is there such concern about a this minor dye ingredient, when a much more potent chemical is present that has been shown to be more immediately harmful? I am referring to the phosphoric acid that has been shown to cause kidney stones. A friend of mine drank a lot of diet Coke over the years and went to his doctor after developing a stone. When the doctor pointed out to him the connection, my friend switched to diet Sprite.
12:49 PM on 03/08/2012
stop eatting. everything gives you cancer. *rolls eyes*
04:07 PM on 03/08/2012
Stop eating NON-FOODS ... as most will eventually lead to cancer. Our bodies were not designed to filter out the toxins we place in it now... in our so call 'food and drink' suppy...
HUFFPOST SUPER USER
Wbischo
10:27 AM on 03/08/2012
The Coca Cola Company should file a lawsuit against CSPI for the statements which contradict what our FDA says and what the Beverage Industry say about the 4-MI. If CSPI can show proof positive that it would increase cancer risk, they would have to do so, and allow the FDA to see the methods of testing and the results they get. California should also be sued for using the CPSI information and placing it above the FDA studies. We have trusted the FDA to oversee what we eat and drink long enough to know it isn't likely they have made a mistake on this, and if California wants to use false information, they should at least say it ''WOULD TAKE 1000 cans a day" to harm a human being, on the warning labels they use because of the CPSI Reported information. I did not drink cola drinks more than a very few times in my life prior to my 21st birthday, yet I DID have cancer early in my life, which I survived after having surgery. I think we would have a much larger indication of there being a carcinogen in colas from the USERS themselves if this study was actually true. I have had from one to three of these drinks almost EVERY DAY, for over fifty years now, and I was already " at risk" I would assume. I get regular tests for cancer,
04:19 PM on 03/08/2012
HUH??? The FDA approves well before they 'test,' and testing is often not done for up to 15 years as they do not have the staff to keep the Pharma and food industry safe! They usually test AFTER THE FACT when people are sick. It is supposed to be self regulated , much like the SEC and the financial regulations are being adhered to, ahem! And of course we know the food industry and Pharma have people's health first and foremost before money right?

Because you do not have cancer now and drink soft drinks, you use yourself as an analogy? Interesting logic at play there... being there are many substances that can be carcinogenic (can give you cancer)... and this names but one such chemical that is in an unnecessary product to COLOUR IT and you want to sue the CSPI?

Does your Doc know you have a cola habit?
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Jay from Ottawa
sovereignty sale, 1.3T OBO
01:49 PM on 03/09/2012
I pity anybody who has any faith in the FDA.
HUFFPOST SUPER USER
Nonnie22
08:03 AM on 03/08/2012
When I read articles like this I always think, not that they're bogus, but that if things were as dire as the implications we'd be stepping over bodies on the sidewalk! I don't doubt that the component that is identified as a problem is a problem and is in dark soda pops, but as another poster mentioned the research is so often done in drastic measures.

Also, when I hear of something that's got the potential to cause cancer I inevitably think "get in line"!
04:20 PM on 03/08/2012
WOW, you would do well hyping for the tobacco industry!