Jack Osbourne, son of Ozzy and Sharon Osbourne, was diagnosed with the autoimmune disease multiple sclerosis.

The 26-year-old new father was "angry and frustrated and kept thinking, 'Why now?'" People magazine reported.

Experts aren't quite sure why the characteristic inflammation and nerve damage occur, but according to the National Institutes of Health, the multiple sclerosis symptoms typically include muscle weakness, numbness or tingling sensations and problems with coordination and vision. More common in women, MS is usually diagnosed between age 20 and 40, and symptoms may start out mild, come and go or become so severe that a person becomes unable to speak or walk.

There is no known cure for MS, although Osbourne says he plans to manage the disease with medication and holistic treatments, according to Time.com.

But he's not the only celebrity to receive a diagnosis or to lend his name to raising awareness for the disease. Below are 12 other famous faces who have been touched by MS.

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  • Ann Romney

    Republican Presidential candidate Mitt Romney's wife's MS is central to his campaign. They often discuss her 1998 diagnosis, as well as how she <a href="http://abcnews.go.com/Health/ann-romneys-ms-highlights-unpredictable-disease/story?id=16221663#.T99GaytYvJV" target="_hplink">managed the disease while raising five sons</a>, ABC reported. <br><br> But she recently had to take a break from campaigning when her symptoms were aggravated. "I start to almost lose my words. I almost can't think. I can't get my words out. I start to stumble a little bit and so <a href="http://www.etonline.com/news/121147_Ann_Romney_on_Recent_MS_Scare_on_Campaign_Trail/index.html" target="_hplink">those things were happening</a> and I thought, 'Uh oh, big trouble,'" she said in an interview with Entertainment Tonight.

  • Montel Williams

    The Daytime Emmy award-winning talk show host announced his diagnosis in 1999, and he started the <a href="http://www.oprah.com/health/Montel-Williams-Battle-with-MS-Overcoming-Depression-and-Pain" target="_hplink">Montel Williams MS Foundation</a> to raise money for research into the disease. <br><br> His <a href="http://www.oprah.com/health/Montel-Williams-Battle-with-MS-Overcoming-Depression-and-Pain/3" target="_hplink">main symptom is pain</a>, he told Dr. Oz on an episode of "Oprah." "I've got pain from my shins to my feet, 24 hours a day, 365 days a year, and it's been there for the last 10 years." Then the pain spread to his face. "It literally feels like you're taking a fork and stabbing me right now. People say, 'How the devil do you deal with this?'" he said. "You have to get a grip."

  • Richard Cohen

    The Emmy award-winning journalist and husband to Meredith Viera <a href="http://www.usatoday.com/news/health/spotlighthealth/2004-07-07-cohen-spotlight_x.htm" target="_hplink">first learned of his diagnosis in 1973</a>, but was reluctant to speak up about it, he told <em>USA Today</em> in 2004. "I always resisted being defined by my MS," he said. "That's why I was obsessively secretive about it in the early years. It never dawned on me that people thought I had a drinking problem. Police even followed me home a few times thinking I was under the influence."

  • Richard Pryor

    The comedian was first <a href="http://www.usatoday.com/life/people/2005-12-10-richard-pryor-obit_x.htm" target="_hplink">diagnosed with MS in 1986</a>, and eventually became debilitating enough to drastically affect his work,<em> USA Today</em> reported. <br><br> He died in 2005 of a heart attack at age 65.

  • Teri Garr

    The actress, well known for her roles in "Young Frankenstein" and "Close Encounters of the Third Kind" was diagnosed with MS in 1999, <a href="http://www.rd.com/health/actress-terri-garr-battles-multiple-sclerosis/" target="_hplink">after 16 years of symptoms</a> like tingling, tripping and stabbing pain, according to <em>Reader's Digest</em>. <br><br> She <a href="http://www.everydayhealth.com/multiple-sclerosis/teri-garr.aspx" target="_hplink">spoke out publicly about the disease in 2002</a>, according to Everyday Health, becoming a pair spokesperson for an MS medication and a National Ambassador for the National Multiple Sclerosis Society, and advocating for research and education.

  • Tamia Hill

    The singer and wife of NBA player Grant Hill opened up on "Extra" in 2005 about <a href="http://telepixtvcgi.warnerbros.com/v2/news/0505/27/3/text.html" target="_hplink">her diagnosis nearly two years before</a>. "I went from being physically active to not being able to get out of bed," she said. <br><br> But she knew she had to push through and <a href="http://www.nationalmssociety.org/online-community/personal-stories/tamia/index.aspx" target="_hplink">speak up about the disease</a>, she said. "I just felt it was important to get it out there and let people know it's not a sign of weakness. You have good days and bad days."

  • Clay Walker

    The country musician was <a href="http://www.nationalmssociety.org/online-community/personal-stories/clay-walker/index.aspx" target="_hplink">diagnosed in 1996 at the age of 26</a>, according to the National Multiple Sclerosis Society, after losing feeling in his right hand and leg. <br><br> Through mediation, diet and exercise, he has regained feeling, continued on in his music career and worked to raise money and awareness of the disease. He was <a href="http://www.nationalmssociety.org/online-community/personal-stories/clay-walker/index.aspx" target="_hplink">named Ambassador of the Year</a> by the National Multiple Sclerosis Society, only the fourth person to receive the distinction in nearly 60 years.

  • Alan And David Osmond

    Alan, entertainer and producer (and brother to Donny and Marie), noticed he was tripping on nothing while he was on stage in 1987 and was <a href="http://www.nationalmssociety.org/ms-awareness-week/alan-osmond/index.aspx" target="_hplink">diagnosed with MS</a> a few years later, he told the National Multiple Sclerosis Society. <br><br> His son, David, known for his turn on "American Idol," was <a href="http://www.nationalmssociety.org/online-community/personal-stories/david-osmond/index.aspx" target="_hplink">diagnosed in 2006</a>, and says one of Alan's favorite sayings -- "I may have MS but MS does not have me" -- keeps him performing. <br><br> <em>Photo: Left to right: Alan, David and Donny Osmond</em>

  • Joan Didion

    The writer, who <a href="http://www.independent.co.uk/life-style/health-and-families/features/lsquothis-is-what-ms-looks-likersquo-2122567.html" target="_hplink">detailed her diagnosis in "The White Album,"</a> told the <em>New York Times</em> she went <a href="http://www.nytimes.com/1979/06/10/books/didion-calif.html?pagewanted=3" target="_hplink">blind for six weeks</a> due to the disease.

  • Michaele Salahi

    The "Real Housewives of Washington D.C." star revealed a <a href="http://www.foxnews.com/entertainment/2010/09/15/exclusive-michaele-salahi-says-multiple-sclerosis/" target="_hplink">17-year battle with MS</a> on a 2010 Fox appearance. She said she hoped to use her fame to help others.

  • Michelle Obama

    The First Lady <a href="http://news.yahoo.com/blogs/cutline/michelle-obama-letterman-isn-t-oprah-where-laughs-231917424.html" target="_hplink">spoke about her father's multiple sclerosis</a> on a recent episode of "The Late Show With David Letterman." "I never knew him to be able to walk, but my dad worked so hard and he loved us so much," she said. "I think from him I learned just absolute, complete unconditional love, the notion that kids really don't need anything but to know that their parents adore them."

  • J.K. Rowling

    The author's mother passed away in 1991 after a <a href="http://www.people.com/people/article/0,,1147497,00.html" target="_hplink">10-year battle with MS</a>, People.com reported. She said that her greatest regret is that her mother didn't live to see the wild success of Rowling's Harry Potter series.

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