Rep. Darrell Issa (R-Calif.) on Friday evoked the Menendez brothers -- the infamous duo responsible for their parents' deaths -- in dismissing Attorney General Eric Holder's claim that House Republicans voted to hold him in contempt of Congress based on shaky evidence and "truly absurd conspiracy theories."

"Well, the attorney general is a bit like, if you remember the Menendez brothers who killed their parents, and if they claimed they were orphans, it would have been equally genuine," Issa told Fox News' Greta Van Sustern. "Ultimately he is saying we don't have the facts. Well, the facts we have points to the cover-up in people in Justice who weren't being given documents."

On Thursday, House Republicans voted for the first time in history to hold a U.S. attorney general in contempt of Congress. The contempt charge came after an 18-month investigation into Holder's role in Operation Fast and Furious, which involved monitoring the transfer of guns bought in the U.S. to Mexican drug cartels and may have led to the death of a U.S. Border Patrol agent.

In 1989, Lyle and Erik Menendez shot and killed their parents in their Beverly Hills mansion before living for seven months off their abusive father's million-dollar fortune.

During their trial, the brothers' attorneys tried to stir sympathy by mentioning that the young men were orphans in the aftermath of their parents' deaths.

After the Mendendez brothers comparison, Issa called Holder "self-serving" for denying that Issa has proof there was a Justice Department cover-up of Fast and Furious.

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  • From left, House Minority Whip Steny Hoyer of Md., Rep. Maxine Waters, D-Calif., Rep. John Lewis, D-Ga., Rep, Charles Rangel, D-N.Y., and House Minority Leader Nancy Pelosi of Calif., right, and many House Democrats walk out of the Capitol during the vote to hold Attorney General Eric Holder in contempt, Thursday, June 28, 2012, on Capitol Hill in Washington. (AP Photo/J. Scott Applewhite)

  • House Oversight and Government Reform Committee Chairman Rep. Darrell Issa, R-Calif., left, and the committee's ranking Democrat Rep. Elijah Cummings, D-Md., go to the House Rules Committee, on Capitol Hill in Washington, Wednesday, June 27, 2012, to argue procedures as the House of Representatives prepares to vote on whether Attorney General Eric Holder is in contempt of Congress because he has refused to give the Oversight Committee all the documents it wants related to Operation Fast and Furious, the flawed gun-smuggling probe involving Mexican drug cartels. (AP Photo/J. Scott Applewhite)

  • Rep. Carolyn Maloney, D-N.Y., left, stretches out her hand to get the attention of Rep. Darrell Issa, R-Calif., chairman of the House Oversight and Government Reform Committee, as the panel considers a vote to hold Attorney General Eric Holder in contempt of Congress, on Capitol Hill in Washington, Wednesday, June 20, 2012. Rep. Elijah Cummings, D-Md., the ranking member, sits between them. (AP Photo/J. Scott Applewhite)

  • WASHINGTON, DC - JUNE 20: House Oversight and Government Reform Chairman Darrell Issa (R-CA) (C) talks with raking member U.S. Rep. Elijah Cummings (D-MD) (L) during a mark up hearing on Capitol Hill June 20, 2012 in Washington, DC. Issa and the committee Republicans called the hearing to vote on holding U.S. Attorney General Eric Holder in contempt of Congress for refusing to hand over documents the GOP says are key to their investigation into the failed Fast and Furious operation. Before the start of the hearing, the White House asserted the documents are protected by executive privilidge. (Photo by Chip Somodevilla/Getty Images)

  • Rep. Darrell Issa, R-Calif., center, chairman of the House Oversight and Government Reform Committee, confers with an aide as the panel considers a vote to hold Attorney General Eric Holder in contempt of Congress, on Capitol Hill in Washington, Wednesday, June 20, 2012. Rep. Elijah Cummings, D-Md., the ranking member, second from left, speaks with Rep. Carolyn Maloney, D-N.Y., who authored an amendment in support of Holder. In a showdown with President Barack Obama's administration, House Republicans had pressed for more Justice Department documents on the flawed gun-smuggling probe known as Operation Fast and Furious that resulted in hundreds of guns illicitly purchased in Arizona gun shops winding up in the hands of Mexican drug cartels. (AP Photo/J. Scott Applewhite)

  • Rep. Jason Chaffetz, R-Utah, center, debates Rep. Stephen Lynch, D-Mass., as the House Oversight and Government Reform Committee considers a vote to hold Attorney General Eric Holder in contempt of Congress, on Capitol Hill in Washington, Wednesday, June 20, 2012. (AP Photo/J. Scott Applewhite)

  • The House Oversight and Government Reform Committee, led by Chairman Darrell Issa, R-Calif., right, considers whether to hold Attorney General Eric Holder in contempt of Congress, on Capitol Hill in Washington, Wednesday, June 20, 2012. Rep. Elijah Cummings, D-Md., the ranking member, speaks at left. In a showdown with President Barack Obama's administration, House Republicans are pressing for more Justice Department documents on the flawed gun-smuggling probe known as Operation Fast and Furious that resulted in hundreds of guns illicitly purchased in Arizona gun shops winding up in the hands of Mexican drug cartels. (AP Photo/J. Scott Applewhite)

  • WASHINGTON, DC - JUNE 20: House Oversight and Government Reform raking member U.S. Rep. Elijah Cummings (D-MD) (R) hears from U.S. Rep. Dennis Kucinich (D-OH) during a mark up hearing with June 20, 2012 in Washington, DC. Chairman Darrell Issa (R-CA) and the committee Republicans called the hearing to vote on holding U.S. Attorney General Eric Holder in contempt of Congress for refusing to hand over documents the GOP says are key to their investigation into the failed Fast and Furious operation. Before the start of the hearing, the White House asserted the documents are protected by executive privilidge. (Photo by Chip Somodevilla/Getty Images)

  • Attorney General Eric holder speaks to reporters following his meeting on Capitol Hill in Washington, Tuesday, June 19, 2012. Holder wants a House panel to drop plans to try to hold him in contempt of Congress, and the panel's chairman wants more Justice Department documents regarding Operation Fast and Furious, a flawed gun-smuggling probe in Arizona. Holder and Rep. Issa met in an effort to resolve their dispute over the investigation of Fast and Furious by the House Oversight and Government Reform Committee that Issa chairs.(AP Photo/Susan Walsh)

  • Rep. Darrell Issa, R-Calif., speaks to reporters following his meeting with Attorney General Eric Holder on Capitol Hill in Washington, Tuesday, June 19, 2012. Holder wants a House panel to drop plans to try to hold him in contempt of Congress, and the panel's chairman wants more Justice Department documents regarding Operation Fast and Furious, a flawed gun-smuggling probe in Arizona. Holder and Issa met in an effort to resolve their dispute over the investigation of Fast and Furious by the House Oversight and Government Reform Committee that Issa chairs. (AP Photo/Susan Walsh)

  • Attorney General Eric Holder speaks to reporters following his meeting on Capitol Hill in Washington, Tuesday, June 19, 2012. Holder wants a House panel to drop plans to try to hold him in contempt of Congress, and the panel's chairman wants more Justice Department documents regarding Operation Fast and Furious, a flawed gun-smuggling probe in Arizona. Holder and Rep. Darrell Issa, a California Republican, met in an effort to resolve their dispute over the investigation of Fast and Furious by the House Oversight and Government Reform Committee that Issa chairs. (AP Photo/Susan Walsh)

  • Attorney General Eric Holder walks through Statuary Hall to speak to reporters following his meeting on Capitol Hill in Washington, Tuesday, June 19, 2012. (AP Photo/Susan Walsh)

  • FILE -In this Dec. 8, 2011 file photo, House Judiciary Committee member Rep. Darrell Issa, R-Calif., left, shakes hands with Attorney General Eric Holder on Capitol Hill in Washington. Holder is proposing to meet with Issa by Monday to settle a dispute over Justice Department documents the congressman is demanding on a flawed gun-smuggling probe. (AP Photo/Susan Walsh, File)

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