EUGENE, Ore. -- Marcus Mariota threw for 198 yards and four touchdowns, including two TD strikes to tight end Colt Lyerla, and No. 2 Oregon beat No. 23 Washington 52-21 on Saturday night.

Mariota rebounded from an interception on the Ducks' opening series to complete 15 of 24 passes and Oregon (6-0, 3-0 Pac-12) won its ninth straight overall dating back to last season, as well as its ninth straight in the series against the rival Huskies (3-2, 1-1).

Lyerla caught three passes for 71 yards, including touchdowns of 10 and 13 yards.

Kenjon Barner, who went into the game ranked 10th in the nation with an average of 121 yards rushing per game, ran for 122 yards and the Ducks built a 35-7 lead at halftime.

Bishop Sankey ran for 104 yards and two touchdowns for Washington.

The two Pacific Northwest teams have a storied rivalry. Huskies' fans remember "The Pick" in 1994 when freshman cornerback Kenny Wheaton saved the day for the Ducks when he intercepted a pass by Damon Huard and ran it back 97 yards for a score. The victory sent Oregon to the Rose Bowl – and a clip is still played on the video scoreboard for fans before every home game.

The Huskies raised the ire of Ducks' fans in 2002 when, after beating Oregon 42-10, the team danced for nearly an hour on the "O" on the 50-yard line at Autzen Stadium.

But because of Oregon's recent domination of the series, the intensity of the rivalry has diminished in recent years. The Ducks' nine-game winning streak is the longest for either side in the series history, which dates back to 1900.

There was little visible contentiousness between the two teams on Saturday night, except for a brief shoving match in the third quarter.

De'Anthony Thomas opened scoring for the Ducks when he wove his way through several defenders for a 16-yard touchdown, set up when the Huskies fumbled on a punt return and Oregon's B.J. Kelley recovered on the Washington 20.

Mariota found sophomore Keanon Lowe with a 21-yard scoring pass before Avery Patterson scored on a 43-yard interception return. It was Patterson's second straight game with an interception for a touchdown.

Sankey, who had also run for 100 yards in each of Washington's previous two games, had a 1-yard touchdown dive for the Huskies to make it 21-7 early in the second quarter.

The Ducks answered with Mariota's 10-yard TD pass to Lyerla. A short time later, a running Mariota hit Josh Huff with a 34-yard catch-and-run.

Rob Beard, who missed a 41-yards field goal in the first half, made a 28-yarder early in the second to make it 38-7. Sankey ran for a hard-fought 6-yard touchdown before the end of the third quarter.

Lyerla opened the fourth with a 13-yard touchdown pass from Mariota, and a short time later Byron Marshall ran for a score to make it 52-14.

Erich Wilson had a 1-yard TD run for Washington with 32 seconds left in the game.

Washington popped into the rankings last week after a 17-13 victory over then-No. 8 Stanford. The Ducks were the Huskies' third top-10 opponent this season. Washington also fell 41-3 to then-No. 3 LSU.

They struggled as much against the Ducks, who went into the game averaging more than 52 points a game and 550 yards in total offense.

Last season Oregon defeated Washington 34-17 in the final game played at the old Husky Stadium before an extensive renovation that is set to be completed for the 2013 season.

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  • Marcus Roberson, De'Ante Saunders, Josh Evans

    Florida defensive backs Marcus Roberson, left, De'Ante Saunders (26) and Josh Evans (9) celebrate with fans after defeating LSU 14-6 in an NCAA college football game Saturday, Oct. 6, 2012, in Gainesville, Fla. Florida won 14-6.(AP Photo/John Raoux)

  • Stefon Diggs, Kevin Johnson

    Maryland wide receiver Stefon Diggs (1) reaches for a pass, that went incomplete, against Wake Forest cornerback Kevin Johnson, left, during the second half of an NCAA football game, Saturday, Oct. 6, 2012, in College Park, Md. Maryland won 19-14. (AP Photo/Nick Wass)

  • Eric Franklin, Jeremiah Johnson, Lovell Jackson

    Maryland defensive backs Eric Franklin (48) and Jeremiah Johnson (14) break up a pass intended for Wake Forest wide receiver Lovell Jackson, center, during the second half of an NCAA football game, Saturday, Oct. 6, 2012, in College Park, Md. Maryland won 19-14. (AP Photo/Nick Wass)

  • Geno Smith

    West Virginia quarterback Geno Smith, right, runs with the ball as Texas defends during the first quarter of an NCAA college football game on Saturday, Oct. 6, 2012, in Austin, Texas. (AP Photo/Eric Gay)

  • Joey Hunt, Tayo Fabuluje

    TCU center Joey Hunt (56) sits on the bench with offensive tackle Tayo Fabuluje (59) during the final seconds of an NCAA college football game against Iowa State, Saturday, Oct. 6, 2012, in Fort Worth, Texas. Iowa State won 37-23. (AP Photo/LM Otero)

  • Laith Wallschleger, Sean Decloux

    Delaware defensive lineman Laith Wallschleger, center, stretches to block a 34-yard field goal attempt by Maine kicker Sean Decloux (37) in the first quarter during an NCAA college football game in Newark, Del., Saturday, Oct. 6, 2012. Maine won 26-3. (AP Photo/The News Journal, William Bretzger)

  • MAINE 26, UD 3

    Maine defensive back Kendall James (5) breaks up a pass intended for Delaware wide receiver Michael Johnson in the fourth quarter of Maine's 26-3 win in an NCAA college football game at Delaware Stadium in Newark, Del., Saturday, Oct. 6, 2012. (AP Photo/The News Journal, William Bretzger)

  • Marcus Lattimore, Shawn Williams

    South Carolina running back Marcus Lattimore is tackled by Georgia strong safety Shawn Williams during the first quarter of an NCAA college football game in Columbia, S.C., Saturday, Oct. 6, 2012. (AP Photo/Brett Flashnick)

  • Josh Lenz, Jason Verrett

    Iowa State wide receiver Josh Lenz (19) goes up for a pass against TCU cornerback Jason Verrett (2) during the second half of an NCAA college football game on Saturday, Oct. 6, 2012, in Fort Worth, Texas. The pass fell incomplete. Iowa state won 37-23. (AP Photo/LM Otero)

  • Clemson quarterback Tajh Boyd celebrates the team's 47-31 win over Georgia Tech in an NCAA college football game Saturday, Oct. 6, 2012, at Memorial Stadium in Clemson, S.C. (AP Photo/ Richard Shiro)

  • Trey Burton, Hunter Joyer, Jabari Gorman

    Florida's Trey Burton, front, Hunter Joyer (41), Jabari Gorman (21) and other Florida players trade high-fives with fans after defeating LSU 14-6 in an NCAA college football game Saturday, Oct. 6, 2012, in Gainesville, Fla. Florida won 14-6.(AP Photo/John Raoux)

  • Connor Halliday

    Washington State quarterback Connor Halliday (12) throws against Oregon State during the first half of an NCAA college football game in Corvallis, Ore., Saturday, Oct. 6, 2012. (AP Photo/Greg Wahl-Stephens)

  • Kendall Brock,Ghaali Muhammad

    Nevada's Kendall Brock (20) dives for the end zone as Wyoming defender Ghaali Muhammad (23) pushes Brock out of bounce before the end zone during the first half of an NCAA college football game in Reno, Nev., on Saturday, Oct. 6, 2012. (AP Photo/Cathleen Allison)

  • Jamison Crowder, Demetrious Nicholson

    Duke's Jamison Crowder (3) battle Virginia's Demetrious Nicholson (1) for the ball during their NCAA college football game, Saturday , Oct. 6, 2012, in Durham, N.C. (AP Photo/The Herald-Sun, Bernard Thomas)

  • Virginia's Clifton Richardson (10) flips over after being stopped by Duke's Walt Canty (4) who is held by Virginia's Jake McGee (83) during their NCAA college football game, Saturday, Oct. 6, 2012, in Durham, N.C. (AP Photo/The Herald-Sun, Bernard Thomas)

  • Conner Vernon

    Duke's Conner Vernon (2) celebrate with fans after Duke defeated Virginia 42-17 in an NCAA college football game, Saturday, Oct. 6, 2012, in Durham, N.C. Vernon caught two touchdown passes and set the Atlantic Coast Conference record for career receptions. (AP Photo/The Herald-Sun, Bernard Thomas)

  • Arryn Chenault, Andy Cruse, Devan Drane

    Cincinnati defensive back Arryn Chenault (25) knocks the ball loose from Miami (Ohio) receiver Andy Cruse (15) in the first half of an NCAA college football game on Saturday, Oct. 6, 2012, in Cincinnati. Cincinnati's Devan Drane (11) caught the loose ball before it hit the ground, for an interception. (AP Photo/Al Behrman)

  • Josh Nunes, Jake Fischer

    Stanford quarterback Josh Nunes runs with the ball past Arizona's Jake Fischer during the first half of an NCAA college football game in Stanford, Calif., Saturday, Oct. 6, 2012. (AP Photo/George Nikitin)

  • LSU FLORIDA Football

    Florida safety Matt Elam, right, forces LSU wide receiver Odell Beckham Jr. to fumble the ball after a long reception during the third quarter of an NCAA college football game at Ben Hill Griffin Stadium on Saturday, Oct. 6, 2012 in Gainesville, Fla. Florida recovered the fumble and defeated LSU 14-6. (AP Photo/Matt Stamey, The Gainesville Sun) MAGS OUT, INDEPENDENT ALLIGATOR OUT

  • North Carolain's assistant strength and conditioning coach Kevin Mitchell, right, cheers on UNC's Giovani Bernard (26) as he romps 51-yards in the third quarter against Virginia Tech during an NCAA college football game, Saturday, Oct. 6, 2012, in Chapel Hill, N.C. (AP Photo/The News & Observer, Robert Willett) MANDATORY CREDIT

  • Dominic Rufran,Duke Williams

    Wyoming's Dominic Rufran (33) misses a touchdown catch against Nevada's Duke Williams (5) during the first half of an NCAA college football game in Reno, Nev., on Saturday, Oct. 6, 2012. (AP Photo/Cathleen Allison)

  • Trey Barrow

    Missouri punter Trey Barrow watches the ball go over his head for a safety during the first quarter of an NCAA college football game against Vanderbilt, Saturday, Oct. 6, 2012, in Columbia, Mo. (AP Photo/L.G. Patterson)

  • Robert Herron,Chris McNeill

    Wyoming's Robert Herron (6) celebrates his touchdown reception with Chris McNeill (80) during the first half of an NCAA college football game in Reno, Nev., on Saturday, Oct. 6, 2012. (AP Photo/Cathleen Allison)

  • MAINE 26, UD 3

    Maine defensive backs, from left, Khari Al-Mateen, Kendall James and Jamal Clay upend Delaware quarterback Trent Hurley, forcing a fumble in the fourth quarter of an NCAA college football game at Delaware Stadium in Newark, Del., Saturday, Oct. 6, 2012. (AP Photo/The News Journal, William Bretzger) NO SALES

  • Ameer Abdullah

    Nebraska running back Ameer Abdullah (8) celebrates a 1-yard touchdown with teammates during the first half of an NCAA college football game against Ohio State, Saturday, Oct. 6, 2012, in Columbus, Ohio. (AP Photo/Jay LaPrete)

  • Braxton Miller

    Ohio State quarterback Braxton Miller tosses the ball to a teammate during the first half of an NCAA college football game against Nebraska, Saturday, Oct. 6, 2012, in Columbus, Ohio. (AP Photo/Jay LaPrete)

  • Mississippi quarterback Bo Wallace (14) scores on a 14 yard run against Texas A&M defensive back Deshazor Everett, left, and defensive back Tramain Jacobs (7) during the first half of an NCAA college football game Saturday, Oct. 6, 2012, in Oxford, Miss. (AP Photo/Oxford Eagle, Bruce Newman) MAGS OUT NO SALES MANDATORY CREDIT

  • Geno Smith

    West Virginia quarterback Geno Smith (12) fumbles the ball as he tries to pass against Texas during the second quarter of an NCAA college football game on Saturday, Oct. 6, 2012, in Austin, Texas. (AP Photo/Eric Gay)

  • Notre Dame players hold the Shamrock Series helmets on the sidelines during the first half of an NCAA college football game Miami at Soldier Field Saturday, Oct. 6, 2012, in Chicago. (AP Photo/Nam Y. Huh)

  • Oregon State fans celebrate a score against Washington State during the first half of an NCAA college football game in Corvallis, Ore., Saturday, Oct. 6, 2012. (AP Photo/Greg Wahl-Stephens)

  • Malcolm Marable, Marcus Mason, Casey Locker

    Oregon State kick returner Malcolm Marable (22) is stopped by Washington State defenders, including Marcus Mason (35) and Casey Locker (22), during the second half of an NCAA college football game in Corvallis, Ore., Saturday Oct. 6, 2012. Oregon State beat Washington State 19-6. (AP Photo/Greg Wahl-Stephens)

  • Allen Hardison

    Nevada's Allen Hardison(60) is comforted by teammates after missing a field goal against Wyoming during the second half of an NCAA college football game in Reno, Nev., on Saturday, Oct. 6, 2012. (AP Photo/Cathleen Allison)

  • Markus Wheaton

    Oregon State's Markus Wheaton carries against Washington State during the second half of an NCAA college football game in Corvallis, Ore., Saturday, Oct. 6, 2012. Oregon State won 19-6. (AP Photo/Greg Wahl-Stephens)

  • Devin Smith

    Ohio State wide receiver Devin Smith is tackled by Nebraska in the first half of an NCAA college football game, Saturday, Oct. 6, 2012, in Columbus, Ohio. (AP Photo/Tony Dejak)

  • Markus Wheaton, Cyrus Coen

    Oregon State's Markus Wheaton carries Washington State's Cyrus Coen (42) during the second half of an NCAA college football game in Corvallis, Ore., Saturday, Oct. 6, 2012. Oregon State defeated Washington State 19-6. (AP Photo/Greg Wahl-Stephens)

  • Oregon fans cheer as their team takes the field for an NCAA college football game against Washington in Eugene, Ore., Saturday, Oct. 6, 2012. (AP Photo/Don Ryan)

  • Mike Leach, Jeff Tuel

    Washington State coach Mike Leach, right, speaks with quarterback Jeff Tuel during the second half of an NCAA college football game against Oregon State in Corvallis, Ore., Saturday, Oct. 6, 2012. (AP Photo/Greg Wahl-Stephens)

  • Texas A&M wide receiver Ryan Swope (25) catches a touchdown pass as Mississippi defensive back Mike Hilton (28) trails late in the fourth quarter of an NCAA college football game Saturday, Oct. 6, 2012, in Oxford, Miss. Texas A&M won 30-27. (AP Photo/Oxford Eagle, Bruce Newman) MANDATORY CREDIT MAGS OUT NO SALES

  • Johnny Manziel, Issac Gross

    Texas A&M quarterback Johnny Manziel (2) throws the ball away as he is sacked by Mississippi defensive lineman Issac Gross (94) in the fourth quarter of an NCAA college football game in Oxford, Miss., Saturday, Oct. 6, 2012. Texas A&M won 30-27. (AP Photo/Rogelio V. Solis)

  • Desmond Jackson

    West Virginia's Desmond Jackson (99) celebrates with teammates after they forced Texas to miss a field goal-attempt during the fourth quarter of an NCAA college football game on Saturday, Oct. 6, 2012, in Austin, Texas. West Virginia won 48-45. (AP Photo/Eric Gay)

  • Max Copeland

    Missouri offensive linesman Max Copeland sits on the Missouri bench after his team lost 19-15 to Vanderbilt in an NCAA college football game, Saturday, Oct. 6, 2012, in Columbia, Mo. (AP Photo/L.G. Patterson)

  • Zac Stacy

    Vanderbilt teammates help running back Zac Stacy, bottom, off the turf after Stacy scored a touchdown during the fourth quarter of an NCAA college football game against Missouri, Saturday, Oct. 6, 2012, in Columbia, Mo. Vanderbilt won the game 19-15. (AP Photo/L.G. Patterson)

  • Charles Sims

    Houston running back Charles Sims, left, celebrates his touchdown run with quarterback David Piland during the second quarter of an NCAA college football game against North Texas, Saturday, Oct. 6, 2012, in Houston. (AP Photo/Houston Chronicle, Nick de la Torre)

  • Andrew Buie

    West Virginia's Andrew Buie reacts after scoring against Texas during the fourth quarter of an NCAA college football game on Saturday, Oct. 6, 2012, in Austin, Texas. West Virginia won 48-45. (AP Photo/Eric Gay)

  • David Piland

    Houston's David Piland, right, looks to complete a pass as his offensive lineman Ty Cloud, center, protects him from North Texas defensive end K.C. Obi during the second quarter of an NCAA college football game against North Texas, Saturday, Oct. 6, 2012, in Houston. (AP Photo/Houston Chronicle, Nick de la Torre)

  • Corey Brown

    Ohio State wide receiver Corey Brown (10) celebrates after returning a punt 76 yards for a touchdown during an NCAA college football game against Nebraska, Saturday, Oct. 6, 2012, in Columbus, Ohio. (AP Photo/Tony Dejak)

  • Al Golden

    Miami head coach Al Golden reacts during the second half of an NCAA college football game against Notre Dame at Soldier Field, Saturday, Oct. 6, 2012, in Chicago. (AP Photo/Nam Y. Huh)

  • Kapron Lewis-Moore, Stephen Morris

    Notre Dame defensive end Kapron Lewis-Moore (89) celebrates after Miami quarterback Stephen Morris (17) was unable to convert on fourth down during the second half of an NCAA college football game at Soldier Field on Saturday, Oct. 6, 2012, in Chicago. Notre Dame won 41-3. (AP Photo/Charles Rex Arbogast)

  • Jordan Poyer

    Oregon State cornerback Jordan Poyer (14) makes one of his three interceptions against Washington State during their NCAA college football game in Corvallis, Ore., Saturday, Oct 6, 2012. Oregon State won 19-6. (AP Photo/The Oregonian, Doug Beghtel)

  • Stephen Morris

    Miami quarterback Stephen Morris squats on the sidelines after failing to convert on fourth down during the second half of an NCAA college football game against Notre Dame at Soldier Field on Saturday, Oct. 6, 2012, in Chicago. Notre Dame won 41-3. (AP Photo/Charles Rex Arbogast)

  • DeVonte Holloman, Godd Gurley, Byron Jerideau

    South Carolina's DeVonte Holloman, left, dives to tackle Georgia running back Todd Gurley as South Carolina defensive tackle Byron Jerideau, right, pursues during the second half of an NCAA college football game at Williams-Brice Stadium in Columbia, S.C., Saturday, Oct. 6, 2012. (AP Photo/Brett Flashnick)