No one likes to be told that he or she isn't "the one," but out of every possible breakup scenario, hearing the words, "It's not you, it's me" has to be the worst.
If your not-so-significant other ends the relationship with this age-old cliché, it might signify that the relationship had more problems than you suspected. If it's not you, then who is it? You're an innocent bystander in your former partner's excuse to be alone? It just doesn't make sense.
Well, you can't win them all, but you can prepare yourself for an "It's not you, it's me" situation by watching the supercut of the line used in TV shows and movies above. At least you know you're not alone!