Mary Bono Mack, a longtime GOP congresswoman from California, lost her bid for reelection on Friday, the AP reported.
Democrat Raul Ruiz won the election.
Ruiz, a Harvard-educated physician ousted the seven-term GOP Rep. with nearly 7,300 more votes out of the approximately 180,000 cast.
Bono Mack is the widow of former congressman and singer Sony Bono and wife of Florida congressman Connie Mack. Mack also lost his election this year. The congressman had been running for U.S. Senate against Democrat Bill Nelson.
Bono Mack conceded the race on Friday, the Press-Enterprise reports.
“Thank you for giving me the distinct honor of serving in the United States House of Representatives for 14 years,” she said in a statement. “After 25 years of public life in the beautiful desert, it is now time for me to start a new chapter in my life. My family and I are very excited about the prospect.”
Bono Mack joined Congress in 1998 after husband Sonny Bono, who held the seat, was killed in ski accident.
CORRECTION: A previous version of this article stated that Connie Mack lost his bid for reelection. The Florida congressman lost his bid for a Senate seat.