CHICAGO — Jose Quintana took a no-hitter into the seventh before David Ortiz broke it up with a one-out broken-bat single, and the Chicago White Sox beat the Boston Red Sox 3-1 on Tuesday night.

Jeff Keppinger hit a two-run homer off Felix Doubront (3-2) in the fifth. Alex Rios extended his career-high hitting streak to 16 with a single and RBI double, and the White Sox won for the sixth time in eight games. They'll try to complete the sweep against Clay Buchholz on Wednesday.

Quintana (3-1) was simply terrific.

The left-hander struck out five and walked two, and he had the fans thinking they just might be witnessing something special. The roars from the stands grew louder with each out as the game wore on, right until Ortiz's bat shattered on a bloop single to center with one out in the seventh.

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  • Chicago White Sox starting pitcher Chris Sale (49) is greeted by teammates after leaving the game in the eighth inning of a baseball game against the Los Angeles Angels, Friday, May 17, 2013 in Anaheim, Calif. Sale struck out 12 batters in 7 and two thirds innings. (AP Photo/Mark J. Terrill)

  • Chicago White Sox's Jose Quintana stands on the mound as Los Angeles Angels' Albert Pujols, background right, rounds the bases after hitting a two-run home run during the fourth inning of a baseball game in Anaheim, Calif., Thursday, May 16, 2013. (AP Photo/Jae C. Hong)

  • Chicago White Sox' Adam Dunn (32) is greeted by teammate Alex Rios after hitting his second two-run home run of the baseball game against the Minnesota Twins in the eighth inning on Wednesday, May 15, 2013, in Minneapolis. The White Sox won 9-4. (AP Photo/Jim Mone)

  • Chicago White Sox second baseman Tyler Greene, right, throws to first base after forcing out Los Angeles Angels' Chris Iannetta during the ninth inning of a baseball game in Chicago, Sunday, May 12, 2013. Luis Jimenez was out at first. The White Sox won 3-0. (AP Photo/Nam Y. Huh)

  • NEW YORK, NY - MAY 08: Alejandro De Aza #30 of the Chicago White Sox is greeted by teammate Alex Rios #51 after hitting a solo home run in the first inning against the New York Mets at Citi Field on May 8, 2013 at Citi Field in the Flushing neighborhood of the Queens borough of New York City. (Photo by Mike Stobe/Getty Images)

  • KANSAS CITY, MO - MAY 6: Jordan Danks #20 of the Chicago White Sox is chased by Mike Moustakas #8 of the Kansas City Royals as he is caught in a rundown in the ninth inning at Kauffman Stadium on May 6, 2013 in Kansas City, Missouri. (Photo by Ed Zurga/Getty Images)

  • KANSAS CITY, MO - MAY 5: Jose Quintana #62 of the Chicago White Sox pitches against the Kansas City Royals at Kauffman Stadium on May 5, 2013 in Kansas City, Missouri. (Photo by Ed Zurga/Getty Images)

  • KANSAS CITY, MO - MAY 4: Starting pitcher Dylan Axelrod #33 of the Chicago White Sox fields a ball hit by Eric Hosmer of the Kansas City Royals and throws to first in the seventh inning at Kauffman Stadium on May 4, 2013 in Kansas City, Missouri. Hosmer reached first on a throwing error by Axelrod. (Photo by Ed Zurga/Getty Images)

  • ARLINGTON, TX - MAY 02: Hector Santiago #53 of the Chicago White Sox throws against the Texas Rangers at Rangers Ballpark in Arlington on May 2, 2013 in Arlington, Texas. (Photo by Ronald Martinez/Getty Images)

  • ARLINGTON, TX - MAY 01: Alejandro De Aza #30 of the Chicago White Sox celebrates a two run homerun against the Texas Rangers at Rangers Ballpark in Arlington on May 1, 2013 in Arlington, Texas. (Photo by Ronald Martinez/Getty Images)

  • CHICAGO, IL - APRIL 26: Conor Gillaspie #12 of the Chicago White Sox dives for a hit off the bat of Evan Longoria #3 of the Tampa Bay Rays during the eighth inning on April 26, 2013 at U.S. Cellular Field in Chicago, Illinois. (Photo by David Banks/Getty Images)

  • CHICAGO, IL - APRIL 25: Adam Dunn #32 of the Chicago White Sox hits a two-run homer during the sixth inning against the Tampa Bay Rays on April 25, 2013 at U.S. Cellular Field in Chicago, Illinois. (Photo by David Banks/Getty Images)

  • CHICAGO, IL - APRIL 24: Tyler Greene #1 of the Chicago White Sox congratulates Alexei Ramirez #10 after a win as Mike Aviles #4 of the Cleveland Indians watches at U.S. Cellular Field on April 24, 2013 in Chicago, Illinois. The White Sox defeated the Indians 3-2. (Photo by Jonathan Daniel/Getty Images)