'Frasier' Premiered 20 Years Ago On September 16

The Famous Voices Of 'Frasier'
385849 12: Cast Members Of Nbc Television Comedy Series 'Frasier' Pictured: (L-R) Jane Leeves As Daphne Moon, David Hyde Pierce As Dr. Niles Crane, Kelsey Grammer As Dr. Frasier Crane, John Mahoney As Martin Crane, And Peri Gilpin As Roz Doyle. (Photo By Getty Images)
385849 12: Cast Members Of Nbc Television Comedy Series 'Frasier' Pictured: (L-R) Jane Leeves As Daphne Moon, David Hyde Pierce As Dr. Niles Crane, Kelsey Grammer As Dr. Frasier Crane, John Mahoney As Martin Crane, And Peri Gilpin As Roz Doyle. (Photo By Getty Images)

"Frasier" premiered 20 years ago on September 16, 1993.

The NBC comedy starring Kelsey Grammer as radio therapist Frasier Crane ran for 11 seasons, ending in 2004. The Frasier character first appeared in a 1984 episode of "Cheers," and became a regular at the bar, before he got his own spinoff.

"Frasier" also starred David Hyde Pierce, Jane Leeves, Peri Gilpin and John Mahoney

Over "Frasier's" 11 seasons on the air, the show was home to many guest stars, but viewers didn't see their faces. The call-in listeners to Frasier's radio show were voiced by A-List talent. The first guest caller was Griffin Dunne and the very last was Helen Mirren. Other guest callers included Christopher Reeve, Bonnie Raitt, Jodie Foster and Jerry Orbach. Hear some of the famous callers in action below.

Reminisce with some classic "Frasier" promo photos below.

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