What Joe Biden Gave Up To Run With Obama

06/13/2014 05:22 pm ET | Updated Jun 13, 2014

As vice president, Joe Biden is arguably the second most powerful man in the country.

However, Biden's former chief of staff Ron Klain said on HuffPost Live Friday that being number two also comes with a huge amount of sacrifice.

"I think people who take on this office understand that and sacrifice, they sacrifice part of their own independent political stature to be a team member," Klain said. "He understood he was giving up his own career, 30-year career, where he was the master of his own ship to be on someone else's ship."

Watch a clip of the interview above.

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