According to Wale, the rap community would have no qualms about accepting an openly gay performer in the mainstream.
"I think 2015 is another world, as compared to 1995," he said. "It used to be taboo to be a part of the gay community, now it's taboo to speak bad on the gay community."
Wale's latest, "The Album About Nothing," dropped March 31 and quickly soared to the top of the charts.
Meanwhile, in 2013, the artist alternately known as Snoop Dogg and Snoop Lion told NME that he wasn't sure if homosexuality would ever be fully acceptable in rap and hip-hop music because of the "masculine" aspects of those genres.
"It's like a football team," the rapper, who has spoken out in support of same-sex marriage, said at the time. "You can't be in a locker room full of motherf**king tough a** dudes, then all of a sudden say, 'Hey, man, I like you.' You know, that's going to be tough."
The full "Larry King Now" interview with Wale can be found here.