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Adam Marsh

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A Sea Change in Academic Research: "Applied" Is No Longer a Dirty Word

Posted: 04/ 3/2012 3:28 pm

Fortune 500 companies have condensed their in-house research and development efforts over the past 20 years to focus on applied research directly related to their business goals. The technology mystique that used to be a significant component of a company's reputation, which justified employing large numbers of Ph.D. researchers and building company research centers, has faded. Bottom line budgets now drive company decisions about how, when and where to expend research dollars, all balanced against maximizing the possibility that those expenditures will translate into future increases in revenue.

So where are the inventors with research freedom to make novel discoveries and fuel the America Invents Act of 2011?

In contrast to the corporate R&D shift, universities and colleges have expanded their capacity for faculty research over the same period. There are many reasons for this development. One positive driver is that research activities in academics can be a source of revenue rather than an expense through extramural grant support. Unfortunately, the success of this model is dependent upon a critical resource: the availability of grant funds. Over the last 10 years in particular, funding sources have not kept pace with the demand of the population of academic research faculty. We are at crossroads where the academic modus operandi of the last 20 years is not likely sustainable over the next 20.

Overall, our research landscape has shifted in two important ways. First, colleges, not Fortune 500 companies, have amassed significant research capacities in this country, both in terms of employing highly skilled and qualified Ph.D. scientists and providing the necessary research infrastructure to support their activities. There is an astounding capacity for discovery and invention in our academic systems. With the shifting center of this activity away from corporations into colleges, there needs to be a new game plan for utilizing this research capacity in the future.

Second, grant funds for basic research are becoming more targeted towards specific goals. There is less interest in funding a scientist with a wild idea (i.e., high risk) because research dollars are a precious resource. All agencies and organizations that oversee the distribution of grant funds need to see productive returns from their financial support (i.e. low risk). And rightly so. These entities have specific goals they must meet in order to be "good stewards" of the funds they control.

In looking for new ways to fund research, one growing alternative is to commercialize academic intellectual property (IP) via faculty, university and business interactions. The goal is to provide value to a business venture while returning a revenue stream to support further faculty research, generate new IP, and continue the cycle. There are a variety of ways to accomplish this goal.

In 2009, I co-founded a biotechnology startup, Evozym Biologics. I was fortunate that the University of Delaware follows a progressive model for fostering faculty commercial activities through its Office of Economic Innovation and Partnerships. The process was reasonable by current standards and I have had support and encouragement throughout; however, the time, energy and effort required for launching a startup poses a real entry barrier for most faculty considering such a goal. I look around at what my colleagues are doing and I see commercial potential in their work. But their basic comment to me about commercialization is: "Who has time for that?" There has to be a more efficient mechanism for basic research discoveries in academia to find focused commercial applications.

New approaches to commercially-enabled academic research are going to present organizational challenges for acceptance and implementation in both business and academics. However, cooperative incubator models between the two could allow faculty to assume balanced functional roles/positions bridging between them to facilitate technology transfer and revenue returns. Ultimately, the goal is to leverage the full research potential of universities to develop technological innovations that will benefit our future economy and society.

This is a sea change in which the principle of separation between business and academics is no longer viewed inviolate. In the 1980s, the idea of applied research in an academic institution denoted science that was more undergraduate technician work than faculty intellectual discovery. Now the word 'applied' is taking on a new meaning of scientific creativity with commercial relevance. And for faculty exploring these paths, there is a growing recognition of the importance of research entrepreneurism in this process. The sea is changing for academic research.

 
 
 
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02:26 PM on 04/04/2012
One thing that you don't mention, but which has had a significant impact in driving this evolution is the Bayh-Dole Act, enacted in 1980. Prior to the Act, inventions developed from publicly funded research were essentially impossible to patent under the theory that the public should not have to pay twice - first to support the research itself and then in the form of higher prices that result from proprietary interests in the resulting technology. Experience over the last 30 years confirms that allowing private intellectual-property rights even when the research was publicly funded has greatly increased commercialization of university-developed technology, to the benefit of the public.

In several ways, the America Invents Act continues the effort. The university lobby managed to obtain some important provisions in the AIA that treat universities differently, and that will likely make commercialization of university research even more attractive.
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Adam Marsh
07:55 PM on 04/04/2012
Good perspective on the timeline. Tech transfer is not new. We just need more of it.

And yes, the Micro-Entity provisions in AIA are very important for commercializing university IP. In a simplistic view, strengthening patent claims potentially decreases some commercial risks, consequently increasing IP values, which raise incentives, and set in motion a positive feedback cycle. Theoretically (caveats aside for now).
04:35 PM on 04/06/2012
Even more than the micro-entity provisions, I was thinking of such provisions as the university exception to the prior-user defense, which should have the effect of making university patents on inventions made with federal funding even more valuable than entirely privately funded inventions. Together with the increase in share of patent-licensing royalties, university inventors should have a greater incentive to commercialize their inventions, at least making some of the difficulties you identified more palatable. Also, the general structure of the first-inventor-to-file system under the AIA, with its tacit encouragement towards publication, dovetails better with the existing practices of academics than does the current system.

The degree to which universities have embraced tech transfer has so far been uneven. There are now a lot of benefits to universities in enabling their faculty to engage in commercialization. At some level, it's still a matter of getting the administrations to fully recognize it - it really can be win-win-win for the university, the inventors, and the public.
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12:53 PM on 04/04/2012
If an invention has merit, it will be taken to market by an entrepreneur. A tenured academic simply does not have the drive to bring something to market.

One thing that may help - is an easy, public, searchable database/site of novel applications/inventions etc....right now everything is buried in journals and little university "fiefdoms"


Not to mention - one would make the invention different enough as to not be forced to pay royalties anyway.
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Adam Marsh
07:33 PM on 04/04/2012
Agree. I'd say that few academics understand the potential markets for their research and are mostly unaware of the work involved to find a 'right' commercial application. Likewise, few businesses have the bandwidth/funds to execute fishing expeditions through technical articles/journals/proceedings. A public searchable database to connect the two is a good idea.

There are other mechanisms. But the key is to foster tech transfer and fill the gaps that have resulted from companies closing or restricting their own internal R&D efforts.
05:02 PM on 04/06/2012
I think the databases of patents at the USPTO, EPO, WIPO, etc. already provide more of this information than is commonly recognized. The free searches they provide need some serious improvement, but there are fee-based searches that can narrow in on material more effectively. The largest problem is often less the availability of the information than the somewhat-arcane way in which inventions are claimed in patents. Even the journal literature can be searched reasonably comprehensively with the fee-based services, but they are nothing close to cheap.