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Are Psychiatric Drugs Contributing to Mental Illness Disability?

Posted: 05/04/10 11:50 AM ET

Investigative reporter Robert Whitaker's Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America (Crown Publishers, April 2010) is the most important book on psychiatric treatment in a generation. I have been in practice for over 25 years and have read hundreds of books about psychiatry, and I can say without question that Anatomy of an Epidemic is the most illuminating book on psychiatric treatment that I have ever read.

Whitaker is the author of four books (including Mad in America, about the mistreatment of the mentally ill), and as a reporter for the Boston Globe, he won a George Polk Award for medical writing, a National Association of Science Writers Award for best magazine article, and was a finalist for a Pulitzer Prize. In the tradition of Michael Pollan, Eric Schlosser, and other investigative reporters who get taken seriously, Whitaker is scrupulous, fair, and describes complex phenomena in a way that is easy to understand.

The starting point of Anatomy of an Epidemic is as follows: In 1987, prior to Prozac hitting the market and the current ubiquitous use of antidepressants and other psychiatric drugs, the U.S. mental illness disability rate was 1 in every 184 Americans, but by 2007 the mental illness disability rate had more than doubled to 1 in every 76 Americans. Whitaker was curious as to what was causing this dramatic increase in mental illness disability.

Since 1955, mental illness disability rates in the U.S. have increased six-fold. At the same time, psychiatric drug use greatly increased in the 1950s and 1960s, then skyrocketed after 1988 when Prozac hit the market, so now antidepressant and antipsychotic drugs alone gross more than $25 billion annually in the U.S. But Whitaker knew that "correlation isn't causation," and that this parallel rise of mental illness disability and psychiatric drug use doesn't necessarily prove anything. In order to get to the bottom of the issue, Whitaker realized he needed to look at two areas:

(1) Do psychiatric drugs, over the long-term, increase the likelihood that a person will be able to function well or do they increase the likelihood that a person will become disabled?

(2) Is it possible that a person with a mild emotional problem may have a bad reaction to an initial drug, and that puts the person on to a path that can lead to long-term mental illness disability? For instance, can a person with a mild bout of depression be given antidepressants that cause a manic reaction, which results in a bipolar diagnosis and chronic disability?

Whitaker took an exhaustive look at what the scientific literature -- one that now extends over 50 years -- had to say about those questions. In an interview with him, I asked him if he could summarize his findings:

The literature is remarkably consistent in the story it tells. Although psychiatric medications may be effective over the short term, they increase the likelihood that a person will become chronically ill over the long term. I was startled to see this picture emerge over and over again as I traced the long-term outcomes literature for schizophrenia, anxiety, depression, and bipolar illness. In addition, the scientific literature shows that many patients treated for a milder problem will worsen in response to a drug-- say have a manic episode after taking an antidepressant -- and that can lead to a new and more severe diagnosis like bipolar disorder. That is a well-documented iatrogenic [physician caused illness] pathway that is helping to fuel the increase in the disability numbers. Now there may be various cultural factors contributing to the increase in the number of disabled mentally ill in our society. But the outcomes literature -- and this really is a tragic story -- clearly shows that our drug-based paradigm of care is a primary cause.
Bipolar disorder in children was once rarely ever seen by psychiatrists, but today well over a million children and teenagers have ended up bipolar after being treated with a stimulant such as Ritalin or an antidepressant. Reading Anatomy of an Epidemic and seeing the magnitude of the mental and physical health problems caused by the pharmaceutical industry, I couldn't help but draw comparisons to Rachel Carson's Silent Spring.


All is not bleak in the area of mental health treatment, especially if one goes outside the United States. In our conversation, Whitaker, offered one of many examples from his book:

In the solution section of Anatomy of an Epidemic, I write of how doctors and psychologists in northern Finland use antipsychotics in a selective, cautious manner when treating first-episode psychotic patients, and their long-term outcomes are, by far, the best in the Western World. So if you believe in evidence-based medicine, then American psychiatry should look to the Finnish program as a model for reform.

Bruce E. Levine is a clinical psychologist and author of Surviving America's Depression Epidemic: How to Find Morale, Energy, and Community in a World Gone Crazy (Chelsea Green Publishing).

 
 
 
Investigative reporter Robert Whitaker's Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America (Crown Publishers, April 2010) is the most impo...
Investigative reporter Robert Whitaker's Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America (Crown Publishers, April 2010) is the most impo...
 
 
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09:25 PM on 06/30/2010
These medications are over-prescribed with both the doctors and the patients being under-educated or flat out lied to by the pharmaceutical companies. Coming off of these medications do lead to SYMPTOMS of bipolarism and other medical conditions. Do the doctors acknowledge (on the whole) withdrawal and that time, patience, support and good self-care will get the patients through withdrawal? Nope. They throw more medications at them. It's a sad, sick merry-go-round. Thank you for doing something to bring this deception and danger to light.
02:45 AM on 06/30/2010
I've learned from personal and professional experience that RECOVERY from Mental Illness can Happen if these 3 main ROOTS of MH disorders are addressed. 1. Malabsorption of Micronutrients ( due to genetic predispositions & GMO influence, to allergies, intolerances, leaky gut ,IBS, Poor liver function , & /or Poor quality food intake /inflammation.) 2.COMPROMISED IMMUNITY -- genetically predisposed.. exasperated by environmental (Prenatal & post birth) heavy metal, pesticide & other TOXIN insults and vaccines, viral and bacterial pathogens like LYME , & parasites, & Candida in brain and other organs & the gut etc. 3. .EMOTIONAL Roadblocks & issues and HORMONAL & Brain function IMBALANCES ie: Thyroid,etc.are addressed. --- I was on Ritalin and Prozac for 10 years successfully.BUT NOW am even more successful using NATURAL MICRONUTRIENTS from http://www.Truehope.com which address the most of the first 2 Roots above. ( These are well researched for Bipolar --including use for Autism, and ADHD) & other spectrum conditions. I also take EFA's, D3 = (35 IU's for every pound of body weight = 5,000 IU's), Vit K2, Enzymes, Probiotics, Thyroid and Adrenal supplements, LW Glutathione p. for immunity, and Homeopathics and liver support. At 63 yrs. I'm healthier than I've ever been in my life with no more daily pain.--either mental nor physical. I do have 2 other family members are now off their Ritalin and Prozac as well .But one son 29 yrs.( adopted and birth mom used cocaine) is still doing WELL on Bipolar Meds. --so I do understand the
09:01 PM on 06/19/2010
If you read this book you would know there is no such thing as a chemical imbalance being cured by these drugs. By saying mental illness is like diabetes you are showing your ignorance about the issue and also that you have bought into the pharma ad hook line and sinker. I hope you don't get talked into taking any of these drugs for any reason ( they are often given for off label uses like menopause ect) and find your life destroyed by them as countless others have. The way it sits right now you are a prime candidate for exactly that to happen. Educate yourself reading this book would be a start.
09:01 AM on 05/07/2010
The insane story of giving powerfull anti psychotics to 2 year olds .http://hsibaltimore.com/2010/02/25/biederman/
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HUFFPOST COMMUNITY MODERATOR
Mensch99
03:00 AM on 05/07/2010
Only the US and New Zealand allow prescription drug ads on TV.
A hypochondriac's smorgasbord.
Take back the airwaves- ban drug ads!
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HUFFPOST COMMUNITY MODERATOR
Mensch99
02:44 AM on 05/07/2010
"Although psychiatric medications may be effective over the short term, they increase the likelihood that a person will become chronically ill over the long term."
Well that's a good thing- if you are reaping the $25 billion.
If you are ill, not so much.

When my Doctor recommends a prescription drug I always ask for the placebo.
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suzjazz
jazz pianist, composer, professor, author
10:41 PM on 05/06/2010
(continued)
People are very quick to blame doctors and assume they are corrupt. Doctors as a group are no more corrupt than any other group of professionals. People are also quick to blame the pharma industry for profiting from disease. It's true that their hands are not always clean, but it is also true that drugs are absurdly expensive because a) it costs so much to research and develop them and b) we do not have single payer health care, which would greatly reduce the cost of medicines by having the government assume most of the cost.
My boyfriend and I have both had cancer and several other chronic illnesses. I for one am grateful for pharmaceuticals. Mental illness is no different from diabetes or other diseases that require daily medications. It's time people stopped ignorantly condemning the drugs that have helped millions of people decide that life is worthwhile.
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suzjazz
jazz pianist, composer, professor, author
10:39 PM on 05/06/2010
We should guard against blanket condemnation of the entire pharma industry and psychiatrists who prescribe medications for mental illnesses. While there are certainly abuses of these medications and some unscrupulous doctors, my experience (and the experience of my boyfriend who also suffers from clinical depression) has been that psychiatrists do NOT only prescribe meds. If they are unable to give talk therapy, they always refer you to someone who will give you talk therapy. Furthermore, maybe we have been lucky, but all of our doctors have been extremely caring and scrupulous about prescribing meds with the fewest side effects. Before psychopharmaceuticals, depressed people committed suicide from despair; if they endured their lives, they were unable to feel joy. And while it is true that there is risk of suicide from certain antidepressants (especially when given to children) there were many, many more suicides before antidepressants were invented. Anyone on these drugs is supposed to be monitored regularly by their doctor.
09:09 PM on 06/19/2010
I think your statistics on suicides are wrong and pharma uses suicide all the time to push the drugs. Most school shooting are done by kids on or withdrawing from antidepressants did you know that tell it to the families of all those dead kids and the ones to come if this industry does not get put in it's place soon. I know the ignorance in the general population is extreme as this is seen a mental illness issue but really it is not. So many off label uses have been suggested for especially antidepressants you will find tons of people who had no mental health issue be given these drugs for physical issues. Guess what happens in these cases? They get drepressed with long term use many also have severe withdrawal some cannot quit taking due to withdrawal even tho the drug is making them extremely sick in other ways like liver heat digestive issues.... that is how intense withdrawal is. If you have not guessed it yet I have lived thru this hell. I am still trying to dig myself out three years later. I have had three years to research and live it. So I do know what I am talking about. If you choose to educate yourself or if you need help getting off these drugs visit paxilprogress.org or topix effexor withdrawal or effexoractivist.org
02:33 PM on 07/01/2010
Yes, his suicide rate claims are absolutely wrong.

After falling for more than a decade, the U.S. suicide rate has climbed steadily since 1999, driven by an alarming increase among middle-age adults, researchers said Monday.

A new six-year analysis in the American Journal of Preventive Medicine found that the U.S. suicide rate rose to 11 per 100,000 people in 2005, from 10.5 per 100,000 in 1999, an increase of just under 5%
06:45 PM on 05/06/2010
from my years in this field i firmly believe that psychiatrists for the most part are as crazy as the patients they treat. They are also beholden to big pharma. We usually know when a drug rep has been to the hospital because the docs start putting their patients on the same drug.
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Mensch99
02:56 AM on 05/07/2010
Seems to me that doctors for the most part are beholden to big pharma.
09:03 AM on 05/07/2010
yup, Yup, and YUP! Ethics is optional today!
11:11 AM on 05/06/2010
One serious problem with Whitaker's thesis is that he resorts to anecdotes and misrepresents papers. He sites a 2007 papers saying that it shows those with schizophrenia have fewer relapses without antipsychotics than those who are on them. A PubMed search of the paper shows an abstract which says nothing of the sort. In fact, the paper simply argues that some people with schizophrenia have a "milder" course where they have few psychotic episodes and don't require constant medication. On the other hand, there are others who are sicker and need constant medication. It does not argue that people with schizophrenia are better off without medications. This is very sloppy reporting on Whitaker's part and really puts into question the rest of his conclusions.
04:47 AM on 05/06/2010
Many classes of drugs have serious, "non-specific" side effects mediated via your autonomic nervous system e.g. antipsychiatric, anti-epileptic, anti-hypertensive drugs.

Better management of our MOOD through lifestyle amendments has a much greater role. Changes in our appalling Western diets, different patterns of exercise (short of Forrest Gump), relationships, surroundings and personal behaviours have far greater preventive impact. My partner ahs had great success with MOOD MAPPING and using lifestyle behaviours to change mood from ANXIOUS or DEPRESSED to CALM or ACTIVE. (www.moodmapping.com)

Drugs have a much smaller place in "treatment".
10:47 AM on 05/05/2010
One thing Big Pharma & our medical system is not looking for is the cause or the cure. Bacterial and viral infections can cross the blood brain barrier and can radically transform a victim's nervous system forever. A few decades ago everyone knew late-stage syphillus could cause schyzophrenia, but how often do psychiatrist investigate that possibility now? How many unknown versions of Mad Cow, Lyme, etc. are proliferating because science doesn't find it profitable enough to address?
We know that the majority of the CNS is located in our gut. What happens when real food is substituted with synthetics? When flavor enhancers like MSG are actually neuro-toxins and instead of correcting a potentially toxic diet, are given Ritalin. Not very nutritous but just clouds the symptoms and moves the illness down the road until it becomes even more serious.
I've witnessed this first hand and its VERY complex. Ultimately its the result of a corrupt system leading to a decaying society. Patient heal thyself!
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Halsey
"There is a price to pay for speaking the truth. T
11:55 AM on 05/05/2010
cotterpin (and Dr. Levine)..thank you...I was going crazy..I mean HUGE hallucinations, could not sleep..and if I did nod off..horrid nightmares...during the day I HAD to paint (I'm not a painter..yet was obsesses)...so..zoloft, serquel, topomax...ended up in lockdown psych... (with true psychotics..I mean the walking dead)...when I got out ..got my butt to an immunologist...said test for EVERTHING!..well...I had super hyper thyoid AND..bloody LYME disease which was eating my brain...synthoid..and 10 days on doxyciline..I was CURED...and curse the pschiatric community for never ever asking if I'd had my blood tested....before throwing all this horrid drugs at me (many were "samples"..that alone is very very telling)..
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Hyla Cass, M.D.
Author, Physician, Speaker
10:47 PM on 06/26/2010
How fortunate for you that you had yourself tested, rather than simply submitting to the diagnosis, and strong medications that don't deal with the underlying cause. Clearly, the brain is an organ that responds to imbalances by showing "brain symptoms" including psychosis. Pretty logical-- and our job as psychiatrists is to investigate the cause, and treat accordingly. Thank all of you for great posts here!
10:30 AM on 05/05/2010
When we resort to investigative reporters to answer questions that are inherently scientific in nature ("Is disease X increasing in incidence or not?" "If so, what is the cause?"), it can only be taken as a sign that things have gone seriously wrong. Both because nothing in their training makes these reporters capable of understanding the scientific aspects, and immense difficulties, of establishing such a proof, and because the scientists themselves must not doing the job.

But, since it is apparently so easy, I ask Mr. Whitaker to definitively answer the questions as to whether autism is increasing in incidence (as it appears to be) or not and what that is due to, and whether Alzheimer's Disease is increasing in incidence (as it appears to be) or not and what that is due to. What with all the chronic neurological diseases there are that appear to be increasing in incidence and for which no known cause has been established, science can certainly use his help.
10:40 AM on 05/05/2010
The cause is clearly known. We've divorced ourselves from nature. We eat terrible things. We don't eat essential, healthful things. We ingest poisons, as we are being poisoned by Big Pharma, Agri-business, junk food purveyors, chemicals, pesticides, etc.

Embrace the natural order and watch these awful ailments disappear.

I'm quite sure the good disease mongering doctors have a pill to give me for my 'attitude'.
09:16 PM on 06/19/2010
I can answer that all those thing you have mentioned have increased in the last 20 years a simple google search is easy enuff.
Why would you think this guy should have answers for the whys of these diseases? Could it be because he has answered the whys of the others?
10:17 AM on 05/05/2010
truth is, to work through intense mental dis-orders requires time, effort and patience in therapy... no one wants to invest so much therefore, as with most things now in our culture of 'instant gratification'... they prescribe pills.. these folks know though, that there is NO recovery through popping pills.. as authentic well-being still requires time, effort and patience through therapy...
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sandalwood
songs of the shamans...
09:56 AM on 05/05/2010
“In this regard, Adam Curtis' documentaries make for fascinating watching... an astonishing excerpt from "The Trap" below.

The Birth of modern Psychiatry: Part 1 of 4

http://www.youtube.com/watch?v=McPnMQ31W_k&feature=relate
09:32 PM on 06/19/2010
I am not surprised with the help of tv ads people now not only know what is wrong with them they know what drug they need to ask their doctor to give them. Sure sounds like a trap to me and a great money making machine.