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Craig Cooper

Craig Cooper

Posted: November 1, 2010 07:38 AM

The debate over the potential benefits and dangers of eating soy is ongoing and often heated. Is soy good for you or should you avoid it? If you do eat soy, how much is OK to eat? There is research to support both sides of the issue. One way to approach the debate is to think of soy like chocolate.

In addition to being a good source of folic acid, copper and magnesium, chocolate and cocoa contain flavanols, a type of flavonoid that has antioxidant properties and a positive impact on blood pressure and improved blood flow to the heart and brain.(1) However, because flavanols are lost during manufacturing, you get the most flavanols from minimally processed chocolate and cocoa, which typically includes dark chocolate rather than milk chocolate and cocoa powder without Dutch processing.(2)

But chocolate, especially milk chocolate, has downsides: It is high in saturated fat and calories, and cocoa butter can raise cholesterol. Chocolate also is a source of oxalates, which can increase the risk of kidney stones for certain people.(3) So when consumed in moderation, the healthiest types of chocolate may offer some health benefits, but wolfing down a few milk chocolate bars every day does not.

Similarly, there are benefits and risks associated with consuming soy and soy foods. If we focus on men's health, there are questions about the impact of this low-fat, cholesterol-free protein source on prostate health. One controversy involves whether soy isoflavones, plant-derived compounds that have very mild estrogen-like (phytoestrogen) activity, can cause, stimulate, or otherwise promote hormone-driven cancers such as prostate and breast cancer.

In the October 2010 issue of Clinical and Experimental Metastasis, researchers reported on the effects of soy isoflavones (genistein, daidzein, and combined soy isoflavones) in established cancers in mice. Genistein decreased mammary tumor growth by 33 percent while daidzein increased it by 38 percent when compared with placebo. Daidzein increased heart and lung metastases while genistein decreased bone and liver metastases. Combined isoflavones did not affect primary tumor growth but they did increase metastasis to the lung, liver, heart, kidney and bones. The authors concluded that consumption of soy foods may increase metastasis. (4)

On the flip side, a recent U.S. Department of Agriculture meta-analysis of "up-to-date available epidemiologic studies" found that "consumption of soy foods is associated with a reduction in prostate cancer risk in men." (5) Specifically, a 26 percent reduction was seen when comparing the highest intake of soy foods with the lowest. The reduced risk rose to 30 percent when the researchers separated out nonfermented and fermented soy foods (e.g., natto, miso, tempeh), and found that tofu and soy milk were associated with the higher reduction in risk, but "intake of fermented soy foods was not associated with the risk." Despite an apparent lack of studies comparing the effects of fermented vs. nonfermented soy foods on tumor development in lab animals, studies of miso show that it inhibits breast, stomach and colon carcinogenesis. (6)

Several other studies support the benefits of soy for prostate health, including two in which genistein slowed the growth of prostate tissues in benign prostatic hyperplasia (BPH or basically, an enlarged prostate) and interfered with the growth of prostate cancer cells. (7) Large population studies also show that when people consume more genistein-rich foods, prostate cancer rates are lower than when genistein consumption is less. (8)

The downsides of soy are important to note, although these disadvantages do not apply to fermented soy foods, as fermentation seems to destroy the toxins in soybeans.

• Soybeans contain high amounts of phytic acid, a type of phytate and a substance that blocks the body's absorption of calcium, magnesium, copper, iron and zinc. Fermentation significantly reduces phytate content.

• Soybeans contain inhibitors that block the action of trypsin and other enzymes needed to digest protein. These enzyme inhibitors are not completely deactivated during ordinary cooking, but they are when soybeans are fermented.

• Haemagglutinin, a clot-promoting substance, is present in soybeans, but it is deactivated during fermentation.

• Soy promotes the formation of an enlarged thyroid, or goiter. The responsible elements appear to be genistein and equol, a metabolite of daidzen. Isoflavones also inhibit thyroid peroxidase, which produces the thyroid hormones T3 and T4. Kaayla Daniels, Ph.D., author of "The Whole Soy Story," suggests that soy's negative impact on the thyroid occurs mostly when isoflavone intake is more than 30 mg daily. (9)

So as with chocolate: a little can be helpful, but too much can contribute to health problems. How much soy is healthy? A detailed review in Nutrition and Cancer reported that soy protein consumption in Japan, where prostate and breast cancer rates are very low, averages between 6 and 11 grams daily, and isoflavone consumption averages between 25 and 50 mg daily. (10) In the United States, some people eat as much as 80 to 100 mg of isoflavones per day in soy milk, soy protein shakes, and protein bars. Here's a general idea of how this breaks down.

First you should know that isoflavone content in soybeans can vary from crop to crop, so we are dealing with averages. One hundred grams of firm tofu (about 3.3 ounces) contains about 15.78 grams of soy protein and 28 mg of isoflavones. Some soy protein bars say they guarantee their isoflavone content to be 3.4 mg per gram of protein, so a bar that contains 14 grams of soy protein would provide 47.6 mg isoflavones. Eating two such protein bars a day would place you near the 100 mg mark. You can see the soy protein and isoflavone content of other soy foods in the "Pennsylvania State University" article "Soy Protein and Soy Isoflavones."

Another issue regarding American soy consumption is attitude. "Soy" has become a buzz word in the food industry, where it is becoming more of a brand than a food. Manufacturers promote soy protein bars, kids' cereals with added soy, and soy protein mixes targeted for athletes as being "healthy." But just because a product contains soy does not automatically mean it is good for you as the soy branding is often a smokescreen for an otherwise unhealthy product containing sugars, additives, artificial flavors and other ingredients of questionable health.

Not all soy products are created equal. Like 99 cent tacos, you get what you pay for. Manufacturers make it cheap, throw on a brand like "soy" and sell it as hard as they can. It doesn't matter whether it is good for you or not. To me, soy is like the professional athlete that signs an unlimited use licensing agreement for his/her name and suddenly finds their image on the side of a cigarette box. Consumers need to read nutritional and ingredient labels and not be swayed by marketing buzz words that grab your attention in the supermarket and have been taken over by the industrial food companies.

Also be aware of the type of soy in foods. When you read ingredient labels look for "soy protein isolate" and "textured soy vegetable protein," which are produced using high temperatures. The by-products of this process are potential cancer-causing substances called nitrosamines and toxic lysinoalanine. Therefore, foods and supplements like soy protein bars and soy protein powders that contain soy protein isolates should be avoided. Highly processed soy products may also contain aluminum, which is toxic to the kidneys, nervous system and brain. (11)

One more critical issue is genetically modified (GM) soy. More than 90 percent of the soybeans raised in the United States are genetically modified. Of these, chemical giant Monsanto's Roundup Ready soybeans made up 92 percent of the U.S. soybean crops in 2008. Along with the fact that no one has definitively determined that GM soybeans (or other GM crops) are safe, soybeans require more pesticides than conventional soybeans, exposing consumers to yet more toxins. (12) And even forgetting the safety of GMO foods for a moment, the fact that a company has named a product on the basis of its resistance to a pesticide should be the biggest red flag to consumers. Monsanto is obviously not a marketing genius when it comes to branding.

You get the point. Be a savvy shopper and read labels more carefully. Make sure the soy foods you enjoy are not genetically modified and do not contain soy protein isolates and other undesirable ingredients, such as fructose, corn syrup and artificial sweeteners and flavors. Check the amount of calories and fat, especially saturated fat, per serving. Soy, like chocolate, can be enjoyed in moderate amounts in certain forms but don't be taken in by the marketing pitches and misleading labels. In the case of soy, like chocolate, you can have too much of a good thing.

See also:

Which Foods Are Good For Men's Health?
46 Things to Avoid for Men's Health

References:

1. Cleveland Clinic, "The Sweet Truth About Chocolate and Your Heart"

2. Cleveland Clinic, "The Sweet Truth About Chocolate and Your Heart"

3. National Institute of Diabetes and Digestive and Kidney Disease

4. Martinez-Montemayor MM et al. Individual and combined soy isoflavones exert differential effects on metastatic cancer progression. Clin Exp Metastasis 2010 Oct; 27(7): 465-80

5. Yan L, Spitznagel EL. Soy consumption and prostate cancer risk in men: a revisit of a meta-analysis. Am J Clin Nutr 2009 Apr; 89(4): 1155-63.

6. Gotoh T et al. Chemoprevention of N-nitroso-N-methylurea-induced rat mammary carcinogenesis by soy foods or biochanin A. Jpn J Cancer Res 1998; 89:137-42; Watanabe H et al. Influence of concomitant miso or NaCl treatment on induction of gastric tumors by N-methyl[n-nitro-N-nitrosoguanidine in rats. Oncol Rep 1999; 6:989-93; Ohuchi Y et al. Decrease in size of azoxymethane induced colon carcinoma in F344 rats by 180-day fermented miso. Oncol Rep 2005; 14:1559-64.

7. Raffoul JJ et al. Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest. BMC Cancer 2006 Apr 26; 6:107; Kazi A et al. Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein. Biochem Pharmacol 2003 Sep 15; 66(6): 965-76.

8. Moline B, Georgel P. Genetic and epigenetic regulation of prostate cancer by genistein. Drug News Perspect 2009; 22(5): 247-54.

9. Daniels K. "The Whole Soy Story." Washington DC: New Trends Publishing, 2005.

10. Messina M et al. Estimated Asian adult soy protein and isoflavone intakes. Nutrition and Cancer 2006; 55:1-12.

11. Melead, Leia, NP.

12. The Organic & Non-GMO Report. More US farmers planting non-GMO soybeans this year.

 

Follow Craig Cooper on Twitter: www.twitter.com/prostatenet

The debate over the potential benefits and dangers of eating soy is ongoing and often heated. Is soy good for you or should you avoid it? If you do eat soy, how much is OK to eat? There is research...
The debate over the potential benefits and dangers of eating soy is ongoing and often heated. Is soy good for you or should you avoid it? If you do eat soy, how much is OK to eat? There is research...
 
 
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11:45 AM on 11/05/2010
Whatever. We're all going to die anyway. More soy please.
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stefanpinto
I'm an actor and a
12:40 PM on 11/02/2010
"More than 90 percent of soybeans are genetically modified." That's frightening. As, I've written, recently,there simply are too many conflicting reports on the true, if any, benefits of soy; I prefer not to recommend soy at all. Beneficial claims come from preliminary studies that are now well over a decade old; new, unbiased research have either mitigated any of those initial claims or proved them entirely inconclusive. - Stefan Pinto, http://www.PintoFactory.com
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Vivian Alicia Evans
01:40 PM on 11/02/2010
f&f!
02:45 AM on 11/02/2010
soy has been traditionally eaten in asian countries in SMALL AMOUNTS and always FERMENTED. That is the ONLY way it can be healthy. Google the subject on the WAPF site. I was disappointed WAPF wasnt on the citations list.

Also genetically modified soybeans are bad not only because they have high levels of pesticides but they also are INHERENTLY bad for your health because mutated proteins cause autoimmune disease and allergies.
12:37 PM on 11/02/2010
Yes, it's also true that some genetic alterations are designed to enable plants to produce their own pesticides and herbacides. It's been shown that sometimes, when these genes enter the gut they can cause these engineered genes to become part of your gut bacteria. This will cause your gut to produce those same pesticides and herbacides inside you. This will continue to happen even if you stop eating GMO's.
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12:48 PM on 11/02/2010
Seriously, what the heck IS it with you people who keep claiming this? You've obviously never been to Asia. GO there and you'll see that not only do they eat plenty of tofu, they also drink lots of fresh, delicious, UNFERMENTED soymilk (as well as, in perhaps more of a modern context, incredible amounts of manufactured soydrinks from the local 7-11). Not just in one isolated country, but, to varying degrees, in all of the 10 that I have visited.

Really, why not just do that instead of feverishly looking up some info on a "website" to prove what you're just so darn sure of? Just go and enjoy Thailand, Malaysia, Taiwan, and their traditional soy products.

Of course only "small amounts" are healthy, which you could say about anything except water and maybe bananas.
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Vivian Alicia Evans
01:42 PM on 11/02/2010
Where would you suggest a person buy organic soy beans and soy products? Have you heard of Monsanto's share of the market?
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HerrMonk
Fighter, Trainer, Nat.Sec.Consultant, Libertine
01:46 PM on 11/02/2010
We're talking traditional Asian food.

Not the industrial by-product known as soy-milk western industrialists created and now sell them.

The US exports most of the soy Asia consumes. GM food-stuff. It's also highly-subsidized by both of us, so it can be a cheap consumable in developing Asian countries.

It's not traditional, and if we weren't subsidizing and exporting it, folks there wouldn't be consuming it.
10:38 PM on 11/01/2010
As a Chinese-American woman who has eaten soy all my life (soy sauce, tofu, fermented black beans) etc., I discovered I was actually allergic to soy in 2003. I think Americans in general are looking for a "magic bullet" ingredient, and soy is currently one of them (along with goji berries and acai). My feeling is that there are some benefits, absolutely, but everything should be in moderation, and more is not better. Esp as the author mentions about soy being so processed and genetically modified. The one thing not mentioned is that soy simulates estrogen in women, so have to be careful with consumption levels there as well.

I blog at www.foodallergyqueen.com

Kishari
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Vivian Alicia Evans
01:39 PM on 11/02/2010
The facts you mentioned about soy stimulating estrogen is one of the scariest for me in addition to the genetically modified food. Thank fully we have more stringent guidelines in Canada about genetically modified food but this could change any time now. Additionally I think you are right about us North Americans looking for the "magic bullet" ingredients. There are none, just sensible eating in moderation and finding out an individuals sensitivities to individual foods. f&f!
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03:31 PM on 11/02/2010
Unfortunately, that is far from "facts" and you do yourself and others a disservice in claiming so. "Simulates estrogen"... good lawd people, just because you pull up some 10-year old discredited theories on Google deosn't make it so.
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02:50 AM on 11/03/2010
Not to put too fine a point on it, but are you also "scared" of apples, carrots, barley, oats, and rice doing the same thing? Like, "terrified" scared or "walk on the other side of the street if you see those foods coming" scared?
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Vivian Alicia Evans
10:15 PM on 11/01/2010
There is not enough evidence out there that I need to have soy in my life to have a healthy diet; therefor I choose not to eat it. I'm not missing anything.
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mtwa
12:52 PM on 11/02/2010
Well, I hope you are not buying ANY processed foods. Most have it. It just like HFCS. It's in everything and is hard to avoid.
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Vivian Alicia Evans
01:34 PM on 11/02/2010
We all have a choice to pick our poison and I prefer to limit all processed food, but to eliminate it entirely I would have to go back 200 years and have my own farm.
06:40 PM on 11/01/2010
GED/DUI Jan doesn't understand how the court system works. This could be why:

http://blogs.phoenixnewtimes.com/valleyfever/2010/10/jan_brewer_dui_report_brought.php
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06:36 PM on 11/01/2010
Ack. I'm really starting to not know what to buy. Maybe I'll just live on roots and berries. Perhaps a steady diet of broccoli.
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Mishal Zeera
12:58 AM on 11/02/2010
Today I thought to myself, Im going to ignore all this stuff and just chew my food more thoroughly.
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rezna
let them eat cake
01:55 PM on 11/02/2010
LOL I feel the same way, and I have that poster (your avatar), one of my favorites. =)
05:13 PM on 11/01/2010
OK, so let me get this straight: organic, non-GMO soy products that are minimally processed, like tofu, tempeh, and edammame, are your best bets for for getting the most out of soy in a healthy way?

Sounds reasonable to me, if you're after a non-meat protein source like I am. Other posts here suggest maybe we need a Rally to Restore Food Sanity, too. Soy's not evil. Soy's not a miracle food. It's one of many good foods if consumed and prepared responsibly. Chillax, peeps: nobody's forcing TVP tacos down your throats.
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HerrMonk
Fighter, Trainer, Nat.Sec.Consultant, Libertine
01:55 PM on 11/02/2010
No, non-GMO soy products that have been fermented, like tempeh, are your best bet.

The raw stuff still has all the nasties (anti-nutrients and phytohormones).
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02:33 AM on 11/03/2010
If you can claim to keep apples, oats, carrots, rice, beer(!), and other phytoestrogen-containing foods out of your diet, I'll admit a grudging but genuine respect – cuz you're hardcore.

For some reason I doubt you've got the stones for it... prove me wrong.
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07:44 PM on 11/04/2010
Rally to Restore Food Sanity - fan #3 & faved!
04:52 PM on 11/01/2010
Soy, used to be good I used to love it, in it's many forms. However now soy is bad. Why?

Because Soy is the most highly genetically engineered food of all. And since genetically engineered pollen spreads easily, even if soy is Organic, it's still genetically engineered.

That means it's dificult to identify the kind of protein your eating, where it came from, Fish, Calfiflower, or Human, you can't know for sure. Since once it's there, part of the process of genetically modifying protein allows certain types of bacteria to bring in genes from any natural source.

Thats right, they've recently discovered this.

Also, they've recently discovered that protein folding, the shape protein takes, plays a very large part in how DNA is expressed. Something that was not even considered when genes are modified. Cecause the analysis of this process is so far beyond are ability to understand. Misfolded protiens play a big part in many diseases, though science does not yet understand why. Many of these diseases like NVCJD are fatal and untreatable. The also can have latency periods of decades.

But there also maybe many new diseases emerge from this technology, due to the lack of understanding of the process by which genes make protein. I guess we will find out in few decades.

oops..
01:33 AM on 11/02/2010
I'm pretty comfortable that, even if my tofu contains some GM features, it isn't human protein.
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12:49 PM on 11/02/2010
Give it a rest. There's plenty of non-GMO soy out there, including the entire Silk line (as far as I'm aware). If you want to avoid human-modified foods, you'll have to cut out corn, beans, tomatoes, and poodles for that matter.
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HerrMonk
Fighter, Trainer, Nat.Sec.Consultant, Libertine
01:56 PM on 11/02/2010
Eat elk.
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Jay Williams, Ph.D.
04:09 PM on 11/01/2010
Aloha Craig and thank you for your informative article. As we can see from some of the comments below, there is still a lot of education that is needed around the subject to counteract the misinformation that has been put out there by the meat and dairy industry. One of the problems we face is the research done on animals with isolated parts of the soy plant as in the study you quoted first in the article. There are NO studies done showing negative responses to soy using ingestion of tofu, tempeh, or edamame beans. None. And as any intelligent person could determine – feeding animals substances removed from a plant doesn’t vaguely resemble humans eating a whole food plant product.

I wrote a similar article regarding soy on Huff Post weeks ago talking about this.
http://www.huffingtonpost.com/katherine-nichols/the-soy-controversy_b_689459.html

Phytic acid and inhibitors are also a big negative in the anti- soy community. Everyone fails to mention that they are also in many other foods that we eat. They are not exclusive to soy. And the thyroid “research” has again not been done on humans eating the soy plant.

I would love to connect with you. Please email me at my website?
Jay@JayWilliamsPhD.com

Keep up the good work
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Craig Cooper
04:25 PM on 11/01/2010
Jay, will do and great article btw.
02:49 AM on 11/02/2010
thats why soy has been traditionally fermented and eaten in small amounts as a side dish. All the other foods with phytic inhibitors like beans and stuff are traditionally fermented as well. you need to read WAPF for the REAL information on whats healthy for human beings to digest.
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02:34 AM on 11/03/2010
Do you eat fermented apples, carrots, rice, and barley? If not you're getting a heck of a lot of those phytoestrogens in your diet. I'm sure you do though – your place must be just one giant pickle-fest!
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ValdaDeDieu
Author: NOCTURNE, BLOODPACT, DEATH MISSION TRILOGY
03:34 PM on 11/01/2010
Soy is BAD all around for most consumers. It's an inflammatory, a cancer-causing agent, an aging accelerator.

Fermented soy appears to have some benefits when used sparingly, or as a condiment. Just like alcohol.
02:50 AM on 11/02/2010
yup yup yup...someone said something that makes sense thank you. you must be a WAPFer? its catching on. :))
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03:27 PM on 11/02/2010
Your obsession with this subject is kind of scary. Refresh my memory, it's all something you heard on some infomercial, right? An "aging accelerator"... that's classic!
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ValdaDeDieu
Author: NOCTURNE, BLOODPACT, DEATH MISSION TRILOGY
05:20 PM on 11/02/2010
As an example of a stooge, you're rather "classic" as well. "yuk"! "yuk"!
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HerrMonk
Fighter, Trainer, Nat.Sec.Consultant, Libertine
03:24 PM on 11/01/2010
The "benifits" of soy are bullocks. Reduced risk of prostate cancer? Yes. That's because it lower testosterone, which is linked to prostate cancer. Know what else reduces it? A healthy lifestyle. No need to chemically nuder yourself to get there.

Ultimately, soy is junk. At it's best, it's fermented and "not that bad". The only reason any argues it should be eaten, is because it's one of the only plant-based sources of a complete protein (good amino profile). Stop pretending we NEED a plant-based protein source, eat meat like a human-being, and drop the soy.
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pinkeyelemonade
Had Enough? Vote Green Party.
03:30 PM on 11/01/2010
Perhaps...but I prefer the taste of soy. :)
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HerrMonk
Fighter, Trainer, Nat.Sec.Consultant, Libertine
03:38 PM on 11/01/2010
Fair enough. Candy is bad for you too, people still decide to partake because of the way it tastes too, but no one tries to argue it's health-food, or "has its place in a well-balanced diet".
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ValdaDeDieu
Author: NOCTURNE, BLOODPACT, DEATH MISSION TRILOGY
03:39 PM on 11/01/2010
Not only is it junk; its label as a "health-food" is probably one of the biggest lies ever perpetuated in civilization...a testament to Big Corp's brainwash. Not one of those CEO's eat their own soy products.
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12:50 PM on 11/02/2010
One thing's for sure, you can ALWAYS be counted on to show up to hate on the soy. What did it ever do to you to deserve this?
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rezna
let them eat cake
02:51 PM on 11/01/2010
Is there a soy milk that you can suggest to me? There are soooo many of them, it's hard to figure out which one is "best", especially with everything in mind that you are laying out in this article. They say non gmo on them, but I find it hard to believe.
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Craig Cooper
03:13 PM on 11/01/2010
Rezna, I don't drink it anymore and use rice milk, when needed, so sorry I can't help on this one.
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rezna
let them eat cake
01:44 PM on 11/02/2010
Craig, thanks for your response. I'll try some rice milks again.
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HerrMonk
Fighter, Trainer, Nat.Sec.Consultant, Libertine
03:24 PM on 11/01/2010
Do yourself a favor, and switch to organic almond-milk.
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Daws
Wants to go to there.
02:46 PM on 11/01/2010
Soy milk irritates my stomach. Not sure what it is but the ingredients are like something out of a chemistry book.
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HerrMonk
Fighter, Trainer, Nat.Sec.Consultant, Libertine
03:26 PM on 11/01/2010
Soy milk is the by-product of the process for collecting soy-oil for industrial purposes.

At some point, someone with great marketing sense, decided that if they dye it white, and add enough sugar to make the bile half-way palatable, and label it a "health-food" enough yuppies would buy it to make a profit.
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12:53 PM on 11/02/2010
Not sure what school you went to, but your chemistry book had stuff like "filtered water, whole soybeans, barley extract, salt, carrageenan, vitamin A", I think someone pulled a fast one on y'all.

(not to say I'm a huge fan of the geenan, and it may be the culprit in your case, but still...)
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Daws
Wants to go to there.
12:35 AM on 11/03/2010
Ingredients in 8th Continent Original Soymilk:

Soymilk (Water, Soy Protein, Soybean Oil, Calcium Phosphate), Sugar, Potassium Citrate, Natural and Artificial Flavors, Magnesium Phosphate, Salt, Sodium Polyphosphate, Dipotassium Phosphate, Soy Lecithin, Carrageenan, Xanthan Gum, Riboflavin (Vitamin B2), Vitamin A Palmitate, Vitamin D2, Vitamin B12

That was just one brand I tried. Yes, the salts are something you'd find in chemistry. I was also being a bit silly (though the stomach irritation was serious). Buzz kill.
02:23 PM on 11/01/2010
I've always found it healthier to replace soy milk with a nice red wine.
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HerrMonk
Fighter, Trainer, Nat.Sec.Consultant, Libertine
03:26 PM on 11/01/2010
Yes