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David Katz, M.D.

David Katz, M.D.

Posted: March 2, 2011 08:54 AM

Whether or not there is bona fide danger in routine use of cell phones is, in fact, still unresolved. As often happens when the stakes are high and the science murky, passions and convictions tend to be running ahead of the data. There are, and have long been, scientists and citizens convinced that cell phones pose a significant threat; and there are, and have long been, counterparts convinced that we all have far more important things to worry about.

Both sides recently received another ear full of information to consider, courtesy of a study published in JAMA.

Investigators from the NIH asked 47 healthy adults to lend them their ears -- their right ears in particular. The researchers put cell phones to both ears and conducted PET scans of the brain (an imaging technique that measures metabolic activity in the form of glucose consumption) with both phones deactivated, and with the phone adjacent to the right ear activated, in random sequence. Activation of the right cell phone was in mute mode so that participants were blinded ('deafened'?) to the intervention.

The study generated three take-away messages that will likely do little to resolve the cell phone controversy any time soon. First, whole brain metabolic activity was unaffected by cell phone activation. Second, brain metabolic activity directly adjacent to an activated cell phone was significantly increased. And third, the researchers have no idea what, if any, clinical significance this has. Yes, they actually said that.

Which leads immediately to a question the rest of us need to grapple with: what do we do with this information in the mean time? For whatever it's worth, my suggestion is to accord it calm respect.

The calmness is easy to justify. A study that shows a change in glucose utilization by brain cells does not indictment of cell phones make. Brain cells routinely burn glucose for fuel, and do so faster or slower based on the work they do. REM sleep, an important indicator of sleep quality and essential to sleep's restorative powers, increases brain glucose utilization on PET scan. As, for that matter, does reading. So if increased metabolic activity in the brain is a cause to fear cell phones, I suppose it might be cause to stay away from your books and your bed as well.

But on the other hand, consider what this new study implies. Increased brain cell metabolism was unrelated to the usual work of the brain, namely thinking. In REM sleep, we are dreaming -- so the brain is at work. When we read, the brain is at work. But why should a radio-frequency-modulated electromagnetic field we don't even know is there -- and thus, can't be thinking about -- change brain function?

It does. The fields emitted by cell phones affect the cells of the brain, no thinking required. Should we be comfortable with this? Can we afford to be complacent when we, and to a greater extent our children, spend an ever increasing proportion of our lives in close proximity to fields we now know silently, insidiously change our brains? My answer is no, which is why we owe the new study some respect, particularly given its context.

We have long known radio-frequency waves penetrate our bodies, as we now know they activate brain activity, but there is no clear evidence they harm us in the process. We are left with a mechanism by which cell phones could conceivably do harm, but no real indication that they do.

The published data, based on many studies and observations in hundreds of thousands of people, remain open to interpretation. One study in the Netherlands examined the issue in over 400,000 people, and found no evidence of harm. A meta-analysis in the Journal of Clinical Oncology, however, concluded there was possible evidence of increased risk of brain tumors from extended cell phone use demonstrated in studies least subject to bias. Invariably, mention is made of the need for more research.

Cell phones have only existed since the 1970s, been in use since the 1980s, and been truly popular since the '90s. So we only have a decade, or at most two, of meaningful data to analyze. Some cancers take two decades or more to develop, so it's possible, if unlikely, that we are waiting for a slow accumulation of damage to start revealing itself. We must therefore consider that absence of evidence is not tantamount to evidence of absence.

And, of course, we don't have intervention studies, with large groups randomly assigned to use cell phones, or place their calls on placebos instead. I'm not sure how placebo phones would work, but I have a sneaking suspicion the study subjects would catch on.

History suggests the possibility of seeing risk that isn't really there. The silicone breast implant controversy persists, despite consistent and rather compelling evidence that the implants do not cause autoimmune disease. The notion that immunization causes autism won't seem to die no matter how decisive the weight of evidence against any such association.

But a great deal of historical precedent cuts the other way. We have cozied up to an impressive array of genuine hazards with a misguided sense of security, including the radioactive radium that made watch faces glow in the dark but caused cancer; mercury used in hat-making that caused neurological disease; lead used in cookware that damaged nerve cells; asbestos in buildings and clothes that is still causing asbestosis and mesothelioma; thalidomide, a sedative that caused birth defects; Vioxx easing joint pain while causing heart attacks; and the list goes on.

If cell phones cause harm, the risk appears to be small, and the harm long delayed. But even one extra case of cancer in 100,000 people after 10 years of use would eventually turn into a huge and unacceptable public health toll. Such a hazard would be very hard to see at this point.

Let's turn to the practical. I will keep using my cell phone, and my kids will keep using theirs. I do think any risks are small. But I cannot be sure the risk is nil, and I am not wildly enthusiastic about the cells in my kids' brains being activated by anything other than thinking. So I will encourage my children to use their phones for good reason, rather than make them a permanent extension of their heads. There is certainly no cause for panic, but I'm not a fan of presumptive complacency.

The 19th century philosopher George Santayana wisely noted that those who do not learn from the follies of history are doomed to repeat them. The folly of rushing into hazards of our own devising with a false sense of security has filled many pages of our history books. Whether cell phone use will prove to be another example is far from certain. But when precedent calls, it is at least prudent to lend our ears.

Dr. David L. Katz; www.davidkatzmd.com
www.turnthetidefoundation.org

 

Follow David Katz, M.D. on Twitter: www.twitter.com/DrDavidKatz

Whether or not there is bona fide danger in routine use of cell phones is, in fact, still unresolved. As often happens when the stakes are high and the science murky, passions and convictions tend to ...
Whether or not there is bona fide danger in routine use of cell phones is, in fact, still unresolved. As often happens when the stakes are high and the science murky, passions and convictions tend to ...
 
 
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HUFFPOST SUPER USER
jacquelinenh
HuffPo Addict
08:38 PM on 03/04/2011
Whatever future studies clarify, wouldn't reducing EMR exposure simply be commonsense?
http://www.healthyfutures.com/blog/cellphoneradiation
http://www.healthyfutures.com/allergysensitivitysolutions/environment-electromagneticenergy
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HUFFPOST SUPER USER
Bigtuna1125
01:31 PM on 03/03/2011
I've written reports on this based on research done. There is no evidence that cell phones cause cancer. The one study that found a link was flawed. It was survey based and asked people with brain cancer if they used cell phones. Because the majority of people today use cell phones you would expect to find that yes more of them use cell phones. The researchers however decided that this meant cell phones cause brain cancer.

A brief lesson in the electromagnetic spectrum. It encompasses all wavelengths a photon (or unit of electromagnetic radiation) from gamma to radio waves. Cell phones transmit and receive microwaves. These waves are smaller than radiowaves but larger than the waves that make up the visible light spectrum (aka the colors we see). Roughly microwaves range form the size of people to small insects. The waves that are known to cause cancer are ultraviolet radiation, x-rays, and gamma rays. These waves are able to cause cancer precisely because they are small enough and vibrate with such a high frequency that they are able to interact with DNA and cause damage. Microwaves, because they are much larger than these other waves are unable to interact with the DNA (and you don't get cancer without DNA damage). You would have better luck saying the color blue causes cancer because its wavelength is closer to the size of the harmful rays than what cell phones emit.
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waldopepper
I'd tell you all about me if you were my friend.
04:02 AM on 03/03/2011
Succinctly, which is uncommon for me.

Are they dangerous? Most agree that they are potentially dangerous.
Therefor, err on the side of caution and do not use them.
Result? No problem, no risk, no harm done.
06:42 AM on 03/04/2011
Note that cordless phones also work in the microwave spectrum, so you need to use only corded phone and speakerphones.
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HUFFPOST COMMUNITY MODERATOR
Quinxy von Besiex
My micro-bio is empty. :(
02:02 AM on 03/03/2011
Given what they have learned in the various studies to date, can't they quantify the maximum risk cell phones could present?

Even if we assumed the scariest studies were absolutely true, they were never suggesting tumors occurred in a huge percentage of the population of cell phone users. It'd be interesting to know the worst case scenario risk, at least it'd be a starting point in assessing possible risk. I do understand that certain exposure (e.g., asbestos) may take 30 - 50 years to cause cancer, but perhaps even in those extremely delayed cases enough patients would present early that you'd suspect there was a danger.
11:12 PM on 03/02/2011
It was a little surprising that you did not mention the deaths from the many idiots who use them while driving. Pedestrians on cell phones are hit by cars and trucks while not paying attention. Also, manners are out the window. Going to a movie is a joke now. People take calls and talk like it's their room. People in public are in their own little worlds. More than the casualties it's the way they have completely changed the way people act socially. I knew it was going to be trouble when in 1991 I was out with my girlfriend having dinner and a table of three girls was each on their cell phones, and not for a few seconds, but for 15 minutes each! They didn't talk to each other that much and it was obvious they were friends. It's only gotten worse since that day, If it was found they were dangerous, it would actually help all of the people who are now socially inept from living their lives through fakebook and cell phones.
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HUFFPOST SUPER USER
realitytrumpsbull
two 'alves of coconut!
09:47 PM on 03/02/2011
I don't know what it does for your sleep, but I think it's really bad for people's manners, and also really bad for how they drive, and they can interrupt work etc. etc. etc. A cellphone can be as much a digital leash as it can anything else, and if you're constantly taking incoming calls, you're liable to end up with the electronic analogue to ADD: You don't concentrate on anything for more than 5 minutes, because there's that next call. 

You also see people carrying and wearing these things, and they're oblivious to other people, their surroundings, and, most importantly, motor vehicle traffic. 

I read a story where a lady got knocked about 30 feet in the air, bounced off the pavement, hit her head, went into a coma, and 3 days later, she died of her injuries. There was at least one cellphone involved, I don't recall if it was her talking, or the driver that hit her, but the point is, your attention gets divided, you're not fully aware of your surroundings, and therefore potentially a hazard to yourself and others. Driving and talking has been rated equivalent to drinking and driving. What about talking and walking, is that the same as public intoxication? 

We have 5 senses, to guide us through life, when one of em is tied up in a phone conversation, the other 4 might not be enough to compensate, plus your mental focus is 'somewhere else'. Something to consider next time you're charging up your airtime minutes. Don't be a digital airhead.
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HUFFPOST SUPER USER
kyosaku
Nothis non carborundum
11:35 PM on 03/02/2011
I moved to Tennessee from California two years ago. I have never seen so many people driving while HOLDING a cell phone to their ear. The roads are narrow and the drivers have bad habits already, so it doesn't help. The technology is available, in Tennessee too, to make talking and driving a bit safer, than using one hand to hold the phone or both to text.

I drive while using my cell phone, not often, because I don't need to. When I do I use a headset, and when I need to dial, I use the voice dial. When I have a phone conversation while driving, both hands are on the wheel. I see no functional difference between that activity, and having a conversation with a passenger in the car. Life is full of distractions, but I really don't want to give up all human contact while driving.

Regardless, I do get your point; and think that a bit of narcissism is in play here. I figure that people who have to have the phone pasted to their head 24/7, are either enamored of their own wit or in need of a boatload of validation. Either way, if the cell fries a few Broca's neurons, they may be better off.

My pet peeve, parents neglecting their children's immediate needs, while gossiping in line at the supermarket...a whole generation of children whose pathology will be attributed to digital abandonment.
08:19 PM on 03/02/2011
This editorial, also published in JAMA, slightly expands on the topic and adds a few things not mentioned in the above exposition.

http://www.avaate.org/IMG/pdf/Jama_2011-305-8-_828-829_Radiaciones_electromagneticas_EDITORIAL.pdf

Worth reading.
06:30 PM on 03/02/2011
At one time I thought that cell phones should be banned because logically radiation would be a problem.

Now I believe that if a minimal amount of radiation is the cost of a modern society then it cell-phones should be welcomed.

However the 'minimal' amount of radiation from a naked-body scanner at the airports by the TSA is unnecessary, doesn't guarantee our safety and is an un-necessary cost for modern society.

Millions of people use cell phones everyday but you have a bigger chance dying from falling down the stairs then a terrorist attack.

My only beef with cell phone companies is stop with the 5 gig limits, break up your monopolies if you don't have enough capital to expand coverage and the infrastructure should be handed back to the government since it's initial investments were paid for by taxpayers.

Cell phones manufactures should also locate a warning label on the device that alerts the user to possible effects from long-term exposure; just like cigarrettes.
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HUFFPOST SUPER USER
exxman
I Am The 99%
08:39 PM on 03/02/2011
"you have a bigger chance dying from falling down the stairs then a terrorist attack."

THAN a terrorist attack, not THEN a terrorist attack. Sorry! It's a pet peeve of mine.

The jury was pretty much in on the dangers of using tobacco when the labels went on the packages. I think warnings on cell phones is a bit premature since there is no evidence of harm from cell phones.
01:21 PM on 03/03/2011
There is evidence of harm from cell phones.
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Uncle Bob
Darwin loves you.
09:31 PM on 03/02/2011
the difference between cigarettes and cell phones is, cigarettes actually cause harm that has been demonstrated statistically over and over.

A notable difference.
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rray
Jazz Fan in Floriduh
05:32 PM on 03/02/2011
Cell phones should be banned on beaches and in parks, why should us non talkers be subjected to their second hand radiation.
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cable1977
Against logic there is no armor like ignorance
06:04 PM on 03/02/2011
Seriously? You do understand that distance is part of the equation here, right? So unless some "talker" is putting their cellphone to your head, you aren't getting any radiation. In fact, even if you were talking on the phone you are getting more radiation from the sun on the beach than a cellphone.

There is no good scientific evidence linking cell phones to cancer at all. If you are really that concerned about electromagnetic radiation, you really should rid your house of all electronic appliances, not just cell phones.
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HUFFPOST COMMUNITY MODERATOR
Quinxy von Besiex
My micro-bio is empty. :(
01:39 AM on 03/03/2011
Not disagreeing with you, since you're absolutely right, but I'll just offer up one scenario where the original commentor might have a point: a fellow passenger in an elevator using a cell phone. In that case the proximity is very close and the interference the elevator and shaft present will ensure the phone will be at the upper end of its power output. (Personally I'm not concerned about it, just making the point that there was at least one situation where one could make the argument.)
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HerrMonk
Son of Apollo
03:31 AM on 03/08/2011
Your sarcasm meter needs tuning.
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TexasDem0
USMC Vietnam combat vet
04:24 PM on 03/02/2011
If you want proof that using cell phones causes brain damage, just look at all the idi0ts who are texting while driving.
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HUFFPOST SUPER USER
DARK STAR
One small step for Man...
04:10 PM on 03/02/2011
While the brain of an adult is probably no longer developing, the brain of an adolescent is, and cell phone exposure may have an affect...just saying.
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HUFFPOST SUPER USER
exxman
I Am The 99%
08:44 PM on 03/02/2011
Cell phone exposure may have the same affect as reading and REM sleep, both of which are beneficial...just saying.
04:08 PM on 03/02/2011
I never have owned a cell phone.I quit cigarettes in 1995,
quit alcohol in the 1980's,along with driving.I stopped pain killers when
my pain stopped.Saw my last Charlie Sheen movie in 1991,
so what might I expect in my all natural and glorious i-future????
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CoastalNC
Good thoughts create good things
03:36 PM on 03/03/2011
Boredom....healthy boredom....LOL
02:35 PM on 03/02/2011
I think that cell phones were primarily intended for convenience and for emergencies. However, I am noticing that far too many use the cell phone to visit with friends and convey the latest gossip, using them for protracted periods of time. During long bus rides, I hear more of other people's business and some of the most lengthy and inane conversations on the planet than I ever wanted to hear. There have been days when I wished that the bus driver could confiscate every cell phone, returning them to each owner only when he or she left the bus.
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CoastalNC
Good thoughts create good things
03:40 PM on 03/03/2011
I upset my family and friends because I leave my cell phone in the car and I only use it on rare occasions if I need to call and ask a question before I get home kinda thing. I mostly have it in case I get in an emergency situation and probably don't pick it up more than once every couple of months. I don't understand the fascination with them for the most part....I need my space now and then.
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NickTAZ
The blue = Job Growth
01:06 PM on 03/02/2011
If cell phones do become our demise then truly the meek will inherit the Earth. The only people left will be in 3rd world countries and the Amish.
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HUFFPOST SUPER USER
fb0252
12:58 PM on 03/02/2011
excellent post! there is that thing that many, few as they be in number, that do have brain cancer at the site, anneurism at the site, aggravated migraines, etc. walked around for years with cell phones plastered to ear. any research on cell phone use in those with brain problems at the site?
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SaveTheMarshMouse
Disco Knockout
02:26 PM on 03/02/2011
As someone who has an accoustic neuroma - I think that cell phone use is a contributor to getting a tumor. I have had a cell phone since 1991 - and I am/was a low minute user (below 50 minutes a month) but ended up with a tumor and hearing loss in my cell phone ear. More studies need to be done on this.

http://www.hearinglossweb.com/Medical/Causes/clacn.htm
06:06 PM on 03/02/2011
I'm very sorry about your tumor. It is almost certainly not due to cell phone use.

The largest studies find no correlation between cell phone use and getting tumors or cancer. As alluded to in the article, in 2006, when cell phones still cranked out more amps than today, scientists found nothing when they tracked 420,000 Danish cell phone users - including 52,000 users who have used cell phones for 10 or more years. The 2008 meta-analysis that found no link included 9 case-control studies with ~5,300 tumor patients, but the 2009 meta-analysis that found a possible link included 23 case-control studies (including studies excluded by the 2008 meta-analysis) with ~12,300 tumor patients. Both studies excluded the Danish results.

Of course, radio waves coming from a cell phone can increase the molecular energy in cells in the vicinity, and increase glucose consumption in cells in the vicinity it seems. But the radio waves and infrared heat generated by a phone simply do not have enough energy to break chemical bonds in DNA strands and cause mutations. There is no evidence that slightly warmer cells have an increase in mutations, thank goodness.