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David Katz, M.D.

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Lifestyle Changes vs. Medication: When Each Is Right

Posted: 06/27/10 12:00 PM ET

I recently saw a patient who, like many others before her, had decided it was time to get serious about her health. She wanted my help with better nutrition, weight loss and modifying her risk factors for chronic disease. Making such assessment in the customary ways, I was fully convinced she was motivated, serious and committed.

Unfortunately, in between visits with me, my patient had a primary care appointment that went rather badly. Apparently disgusted that the patient was not taking a recommended medication, this primary care doctor derided the value of lifestyle interventions and told the patient, "It won't be my fault if you leave here and have a heart attack!" She also, apparently, summed up the possibility that weight loss might not fully reflect body fat loss (and muscle gain) as "bull!" I recently learned of all this when the patient called me, confused and distraught.

With my patient's permission, I hope to speak soon with my colleague and attempt a meeting of the minds. For the time being, though, we have a situation nicely summed up by Cool Hand Luke: "What we've got here is a failure to communicate." Apparently, Luke had just left his doctor's office.

My patient did, indeed, have chronic disease risk factors, including slightly elevated blood pressure and cholesterol, along with early signs of diabetes risk. She is well aware of this, having addressed it with her primary care provider on prior occasions. She had been prescribed medication for lowering her cholesterol, but had not tolerated it well. She came to see me to explore other options.

Those other options are readily available. The American Heart Association, the National Heart, Lung, and Blood Institute and the National Cholesterol Education Program all recommend lifestyle changes -- diet, exercise and weight control -- as the primary approach to cholesterol lowering. The method is referred to as "therapeutic lifestyle changes," or TLC.

The American Diabetes Association places an emphasis on TLC for both diabetes prevention and management, although in the case of management, medication is used as well. The Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (I have always felt their name could do with a makeover!) also front-loads with TLC as the first and best method for controlling elevated blood pressure.

The dietary recommendations of these diverse groups -- and, for that matter, the American Cancer Society -- are noteworthy for overlap. By and large, the emphasis is on foods that are close to nature, minimally processed and rich in nutrient value: vegetables, fruits, beans, lentils, whole grains, nuts, seeds, lean meats and fish, eggs, low-fat dairy. Regular physical activity at a moderate level, and the weight control that generally results from eating well and being active, are common recommendations as well.

Evidence that this basic approach is effective when truly followed is decisive. Studies such as the Lyon-Diet Heart Study have shown that a Mediterranean diet based on the foods above lowers the risk of heart attack in high risk individuals by as much as 70 percent. The Dietary Approaches to Stop Hypertension (DASH) studies have shown that a mostly plant-based diet with low- or non-fat dairy can lower blood pressure as effectively, and more safely, than medication.

The Diabetes Prevention Program showed that lifestyle was twice as effective as the drug metformin in preventing diabetes in high-risk individuals, reducing its occurrence by 58 percent. The Portfolio Diet study by my friend, Dr. David Jenkins at the University of Toronto, proved the principle that diet can lower LDL cholesterol as effectively as statin drugs.

So, there is nothing at all radical -- particularly in a patient who is reticent about taking drugs -- in attempting to modify cardiometabolic risk with a lifestyle intervention.

My patient and I did exactly that, with gratifying results. Between her first visit and her follow-up, she had already lost six pounds by making sensible and sustainable changes to her diet and physical activity patterns. Her blood pressure was lower at follow-up as well; blood work is pending. Because she has been exercising vigorously, it is likely the six-pound weight loss does not fully reflect the loss of body fat, and gain of muscle. We will be doing a body composition test to verify this.

The primary care doc simply refuted all of my advice to the patient, rather than speaking with me. The result was a patient caught between competing medical opinions, and probably trusting both of them less as a result. TLC often doesn't work for lack of follow through; when adopted well, it works well. This patient was doing a great job and deserved encouragement, not discouragement. She got "bull!" from my colleague; from me, she gets: "You go, girl!"

There is no question in the scientific literature that body fat loss can greatly exceed weight loss in someone who is exercising and gaining muscle. My most noteworthy personal experience with this was on the TV show, Celebrity Fit Club, when I supervised weight loss in the over-450-pound comedian, Ralphie May. When the scale wasn't moving, despite Ralphie's diligent efforts, we used body composition analysis to track his progress -- and it showed a dramatic shift from body fat to muscle.

TLC is slower in its effects than medications such as statins, or antihypertensives. But it is ultimately both safer and more potent. Lifestyle can reduce chronic disease risk by 80 percent; no single drug comes close. I of course recommend medication use when TLC isn't getting the job done, for whatever reason.

As for this patient's risk of walking out the door and having a heart attack, I see that differently. We can think of medical danger as being too near a fire: there is the risk of getting burned. This patient, however, was walking briskly away from the fire. No immediate need to put on a suit of asbestos.

In my current practice -- labeled integrative care -- we are very accustomed to stating explicitly that the patient is the boss. We rely on a model for using evidence in treatment decisions called CARE, clinical applications of research evidence, that emphasizes five considerations: safety, effectiveness, quality of scientific evidence, available alternatives and patient preference. Each of these matters, and warrants discussion.

Doctors need to talk to their patients. We also need to talk to other doctors about the care of our patients, so patients are not left in a no (wo)man's land of conflicting opinion. In that divide, we've got a failure to communicate that could readily result in a more fundamental failure: the failure to meet the needs of our patients, and help them be well.

 

Follow David Katz, M.D. on Twitter: www.twitter.com/DrDavidKatz

I recently saw a patient who, like many others before her, had decided it was time to get serious about her health. She wanted my help with better nutrition, weight loss and modifying her risk factor...
I recently saw a patient who, like many others before her, had decided it was time to get serious about her health. She wanted my help with better nutrition, weight loss and modifying her risk factor...
 
 
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11:50 PM on 06/28/2010
"My patient did, indeed, have chronic disease risk factors, including slightly elevated blood pressure and cholesterol,... She is well aware of this."......"Apparently disgusted that the patient was not taking a recommended medication, this primary care doctor derided the value of lifestyle interventions and told the patient, "It won't be my fault if you leave here and have a heart attack!"" ......So what fantastic medication was the women refusing.... the hypertension drug that have never been show to reduce heart attacks....http://www2.cochrane.org/reviews/en/ab002003.html The link says that beta blockers one of the most widely used hypertension drugs simply are no better than placebo at preventing heart attacks or the miracle statins which again have never been proven to save lives benefit women. Interesting article... http://www.dailymail.co.uk/health/article-432395/Statins-
truth.html " Those who are taking statins to lower their cholesterol may well be confused about whether it is worth it and how safe they are.
....Last week an article in the medical journal The Lancet claimed the drugs don't benefit women or elderly men if they don't have a cardiovascular problem, while for younger men, taking statins only slightly reduces the risk of heart attack if they'd never had an attack.

Read more: http://www.dailymail.co.uk/health/article-432395/Statins-truth.html#ixzz0sD4ysSAp..... The MD appears to be just plain wrong
08:17 PM on 06/28/2010
What a great article! I can't tell you how many patients come into my office that take several medications and they tell me that no one ever discussed lifestyle changes with them before putting them on meds. They would be willing to try TLC but most of the time they don't even know where to begin because no one ever took the time to discuss it with them in an individualized way. I'm not against medication but I certainly don't think it should be a first line of defense, ESPECIALLY when there are so many alternatives to try!

I am so happy to read about Dr. Katz's approach to well-being, it's completely refreshing.
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HUFFPOST SUPER USER
time4truthnow
Truth about vaccinations activist
08:49 PM on 06/28/2010
I'll tell you what's refreshing, you're both refreshing. Seeing Dr. Katz say he labels his current practice, "Integrative Care" was even more than refreshing.
10:33 AM on 06/28/2010
Due to having IBS, and even though I ate a conventional healthy diet, I switched to the IBS diet, from helpforibs.com. My IBS symptoms improved 80% within days. After 6 months, I had followup blood tests from my doctor: My cholesterol went down significantly, my blood sugar went down to normal, and my LDL went down. Not only that, but I lost 10 lbs and my blood pressure went down by about 20 points, to a lower level than when I was younger. I do take BP pills, have for 10 years. My BMI went from overweight to normal. These changes are predicted in the book: IBS the first year, but I bought that book long after I had the improvement.
ThatsTheTheWayItIs
religion, ideology, partisanship are delusional
09:01 AM on 06/28/2010
The reaction from the "primary doc" was typical.

I heard a British MD argue that "nutrition has no effect on longevity". That's irresponsibly false.

The medical industry denies the value of ANY treatment except their scans, surgeries and drugs.
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HUFFPOST SUPER USER
assumetheopposite
Capitalism is sin. Acts 4
05:00 PM on 06/29/2010
That's because there's no profit in abolishing trans fats, MSG, artificial sweeteners, HFCS, etc., eating your veggies, and just saying *no* to caffeine, alcohol, tobacco, and all other drugs. Medicine as we know it is not science at all but ***capitalism***, a theory that failed in 1929 and has been propped up by bone-crushing government subsidies since 1933. For every Mideasterner killed in the illegal foreign wars, hundreds of Americans are killed, permanently disabled, or their lives ruined by the equally immoral wars on our bodies and minds right here at home.
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jeffrey678
You don't happen to make it. You make it happen.
08:16 AM on 06/28/2010
Soft drinks are the MAJOR CAUSES of chronic disease in America. The American Heart Association published this study in 2007, http://circ.ahajournals.org/cgi/content/full/116/5/480?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=diet+and+regular+soft+drinks&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
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OMEGA MAN
A wise man learns by the mistakes of others, a foo
08:35 AM on 06/28/2010
WOW ! Even DIET soda ! Diet or non-diet soda can cause diabetes.
08:05 AM on 06/28/2010
Honestly, stop eating fast food and soda, get off your couch, stop smoking, stop being lAzy. Medication isn't going to solve what is realistically a failure of lifestyle; at best it will mitigate it.
ThatsTheTheWayItIs
religion, ideology, partisanship are delusional
09:03 AM on 06/28/2010
According to leading diet researcher, exercise does not cause weight loss. As he puts it "you just get hungrier". Consider that a 3 mile walk in an hour burns 300 calories, but you burn 100 an hour at rest, so you're only burning 200 extra calories - less than two slices of bread.
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assumetheopposite
Capitalism is sin. Acts 4
05:02 PM on 06/29/2010
Yes, exercise is only a secondary course of action. Dismantling of agribusiness must come first. No one is going to go to a speakeasy to get MSG, HFCS, trans fats, etc.
04:09 PM on 06/30/2010
So, if you exercise, and don't eat an extra 2 slices of bread, you'll lose weight. Right?
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Eartha
Live and learn from fools and from sages
07:59 AM on 06/28/2010
The current state of prescribing medications is still the equivalent of throwing darts at a board. Try changing everything lifestyle wise, before entering the dart game.
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GrownupStewie
04:41 AM on 06/28/2010
is it me or did that one girl in the middle, in the picture look like she was floating? and possibly a very tiny person lol...i know she is standing back, but it looks like she's floating
This user has chosen to opt out of the Badges program
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12:00 AM on 06/28/2010
Being completely dedicated to 150 minutes or more of good exercise each and every week without fail will change your life, forever.

And cut your meds costs, too.
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Vitorio
Healthy, Educated America will always prosper.
09:59 PM on 06/27/2010
some interesting posts, do look at all of the regions of the world with centenarians and you will find peoples that don't take drugs but live naturally, eat enough to live well and exercise daily.
08:55 PM on 06/27/2010
You need to be your own health care advocate. Most Md's follow the AMA playbook and are intolerable to their advice being challenged or a patient not following their protocols. I remember so many arrogant attitudes when I was overly medicated years ago, experiencing side effects that continue to this day. The drugs I was given were Kenalog 40-20mg 5 injections over the course of 2 months & Cipro after surgery. The combination of the two caused a wide range of side effect. One of the side effects was a CNS disruption that caused the shakes. My primary sent me to a neurologist who, after reading my chart asked "what is a uterine suspension?" I explained I did not need a hysterectomy because there was no disease in the organ. He just looked at me. So he begins the neurological exam and out of the blue says "what kind of Dr. do you have? I would have made you have a hysterectomy." Exam finished, I got my purse & coat, opened the door and he say "I'm not finished" and I said " yes you are" & left. I knew from the moment I sat across the desk from this guy he was going to dictate what I needed and there was no discussion because when I spoke he didn't pay attention or acknowledge I had spoken. During the exam I thought, he works for me. I'm paying for his services. I'm not paying for this.
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assumetheopposite
Capitalism is sin. Acts 4
05:10 PM on 06/29/2010
Patients need to form a ***union***, where the well-educated and high-IQ can accompany and advocate for the poor and working class at their appointments. There is serious need for collective bargaining. Everyone subjected to this unnecessary surgery should form a class and charge false imprisonment and aggravated assault and battery. One need not have a PhD in sexual politics to guess that this doctor was not about to give you a consciousness-preserving nerve block for this surgery.
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HUFFPOST COMMUNITY MODERATOR
moonflowerjewelry
Buy American made, no excuses.
08:10 PM on 06/27/2010
I agree wholeheartedly in terms of drugs that are used to combat the symptoms of years of self abuse.
I don't throw the baby out with the bathwater, however. I take a mood stabilizer that keeps me from boinging around like a rubber band. I have a close friend who takes anti psychotics so she can hold down a job vs. be walking around on the streets gibbering in a language only she and the voices in her head can understand. I'm throwing this out there because lots of clean-living folks think that fresh air, healthy food and exercise can cure brain disorders... I've heard it all before... I know I am sort of rambling off topic...
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RhiannonRings
Childfree and loving it!
08:12 PM on 06/27/2010
I agree, I'd be a mess without my meds, that I know from experience.
09:49 PM on 06/27/2010
I think that most people would agree that meds can be necessary in many situations, but are often overprescribed.
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BevInSoCal
Worth the trouble
07:29 PM on 06/27/2010
For me, it was a combination of things. First, I got rid of the notion that I wanted to lose weight to look better; I had to lose weight because of my health. Then I went on a short-term course (3 months) of Meridia, lost 45 lbs., had both knees replaced, then started an exercise program. I also started using the Slim-Fast program, tailored to fit my needs, and ended up losing 190 lbs. At only 5', I weighed 332 in December of '05, and now it's 142. It took a true "moment of clarity" to face this weight issue. I don't care how much you think you're happy being overweight; when you hit 45 years old, sugar, your eyes will open. I just hope it's not too late for you!!
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RhiannonRings
Childfree and loving it!
08:14 PM on 06/27/2010
Good for you, you did what you needed to do! I'm 46 and having the same moment of clarity re my weight and health. I think the forties are a wake up call for lots of folks!
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Chas53
08:44 PM on 06/27/2010
Go plant-based. Eat for Health, by Joel Fuhrman MD
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yogajan
Well behaved women rarely make history
09:23 PM on 06/27/2010
I agree with this suggestion. Dr. Fuhrman's book has been an eye opener for me. It is amazing how satisfying the food can be when it is natural and healthy.
09:51 PM on 06/27/2010
In Defense of Food is pretty good, too. "Eat food, not too much, mostly plants."

Note: by "food", the author means "food that your grandmother would recognize".
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SShaw490
06:59 PM on 06/27/2010
I find that doctors who demand their patients follow their treatment, and their treatment consists solely of medication, are not doctors - they're insurance claim filers. Any doctor who tells me that drugs are more effective than lifestyle changes is a doctor that I won't go see any more.

Unfortunately, that's most doctors. So I don't go to the doctor. He can figure out how to get his insurance claim quota done without my help.
06:15 PM on 06/27/2010
Isn't this endemic to our health care system, though? Why is it set up so that the right hand doesn't know what the left hand is doing? The best quality care comes when a team of professionals communicates--and that means LISTENING as well as sharing. This is true whether it's a patient with obesity and high blood pressure or a child with multiple developmental delays and behavioral issues that are related. Why is it so difficult to get past that "failure to communicate"? Should the patients be calling meetings, even if it means everyone gets on a conference call? It's a little crazy, in my opinion.

http://www.sensorysmartparent.wordpress.com