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David Katz, M.D.

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Sugar, on a Slippery Slope

Posted: 02/08/2012 7:20 am

A commentary published last week in Nature argues for the regulation of sugar as a toxic substance. The authors and I agree about ends -- reducing sugar intake -- but have some potential differences about means.

The notion that sugar is a "poison" was established when a lecture by Dr. Robert Lustig espousing that view went viral. Dr. Lustig has made the same case in peer-reviewed articles, and he and his co-authors do so again in last week's commentary.

While the construction of alarming tables and figures demonstrating the calamitous effects of sugar (and specifically, fructose -- Dr. Lustig's particular nemesis) can be defended with legitimate science, it is nonetheless something of a distortion. Even more calamitous pathways could be mapped out for oxygen, which in excess is not just highly toxic, but lethal in rather short order. Oxygen, per se, is not poison of course. The dose makes the poison.

So, too, for sugar -- including fructose. Our excessive consumption of it is the poison.

There is no question that excess sugar is one of the great liabilities of the modern diet, and consequently, one of the great liabilities of public health. Excess sugar intake is implicated in everything from obesity to diabetes to coronary artery disease. Because excess consumption of sugar induces hormonal imbalances -- notably high levels of insulin -- which in turn foster inflammation, excess sugar intake is linked to cancer risk as well. Finding effective ways to reduce ambient sugar intake is not only warranted, but rather urgent -- as we confront epidemics of obesity, diabetes and associated chronic diseases.

Dr. Lustig and colleagues argue for a modest tax on soda and for restricting sales of "fizzy" drinks and candies during school hours. I support these proposals. There is no reason why schools should be propagating the consumption of solid or liquid candy by students. As for the tax, arguments that it is an unfair burden are fatuous. People who really want soda can by and large afford the extra penny, and people who can't afford the extra penny should perhaps consider that they can't afford to squander such limited food funds on the empty calories of soda. Certainly if they can't afford an extra penny for soda, they can't afford to get -- and treat -- diabetes! If the tax nudged them to drink less soda and more water, it would be as intended. There is no inalienable right to afford soda in the Constitution.

The authors also propose subsidies in federal programs, such as WIC and SNAP, for healthful foods. Here, too, we agree entirely.

But they also suggest an age limit for purchasing soda. They propose regulation or a ban on television commercials for "products with added sugar." As stated, this would encompass virtually all breakfast cereals, many breads, all desserts, many salad dressings, ketchup, jam, pancakes, deli meats and much more. That may be what the authors intend.

Whether it is or isn't, it hints at the challenges in determining just where nutrient-based regulations should begin and end. It also shows why the tempting comparison to tobacco (made by the authors) is of limited utility. Tobacco can be banned outright. Food -- and most ingredients in food -- cannot. And even the most healthful diets on the planet generally contain some foods with added sugar. The dose makes the poison.

Regulating nutrients, per se, is a slippery slope. If we regulate sugar, we should certainly regulate trans fat -- which is far less important to palatability, and more toxic in smaller quantities.

But what about sodium, which the Center for Science in the Public Interest has argued kills 150,000 Americans a year? The Nature authors argue that fructose should not have GRAS (generally recognized as safe) status from the FDA; the same argument has been made about sodium. Do we regulate both?

And if so, what about the real culprit in much of what most ails modern public health: calories? The root cause of most diabetes and much other chronic disease is obesity, and the most indelible link between weight and food is not composition, but quantity. If sugar is poison because of the harms of excess, so too -- and then some! -- for calories. Shall we regulate the quantity of food people eat?

Even if we were to isolate sugar as public health enemy number one, its regulation would draw us into challenging subtleties. There is, of course, sugar (and fructose) in fruit, which Dr. Lustig and colleagues clearly do not mean to indict. But what about canned fruit packaged in fruit juice? Where, exactly, would the regulation start, and end? If we did succeed in making sugar in all forms the enemy, what is to prevent the food industry from making far more use of artificial sweeteners -- and what do we know about the health effects of that?

I have concerns that the bounds of sugar regulation are not clearly defined -- and would prove challenging, at best. I have greater concerns that excessive focus on any given nutrient, good or bad, invites the proverbial failure to see the forest for the trees. We have cut fat, and eaten poorly. We have cut carbs, and eaten poorly. We could now cut sugar, and still eat poorly. We have decades of dietary debacles to show we are unlikely to get to health one nutrient at a time. It is past time to start thinking about the overall nutritional quality of foods, and diet -- which are what truly matter to health outcomes. Sugar is an important component of this, to be sure -- but only a component.

Just as a preferential focus on any given nutrient may divert attention from the overall nutritional quality of foods, a preferential focus on the food supply can divert attention from the potential power of the food demand. Ultimately, food manufacturers committed to their bottom lines care about one thing above all: keeping the customer satisfied. If we empower people with readily interpretable information about nutrition, they can act on it.

We do not need randomized trials to prove that the food demand trumps the food supply; we have seen natural experiments prove it. When the Atkins diet was wildly popular, every supermarket in the country filled up with low-carb foods, no regulation required. The challenge is to convert this latent power into a force for genuine good, by directing it at the overall quality of nutrition rather than the next nutrient preoccupation du jour.

Empowering the public to demand better nutrition -- and less sugar -- involves finding effective ways of telling people some things they never knew they never knew.

For instance, you likely know that the first item on an ingredient list is the most abundant. So, if you are concerned about your sugar intake and want some apricot jam, which is better: the one with sugar as the first ingredient, or the one with apricot as the first ingredient?

It's a trick question: they may be identical. What manufacturers do sometimes is "divide" the sugar added to a food into multiple aliases -- sucrose, corn syrup, and so on. If no ONE of these is more abundant than apricot, they can list apricot as the first ingredient. But what really matters is that added up, sugar by all these different names is, in fact, the most abundant ingredient -- just as it is in the competing jam that lists sugar first. Such practices undermine a consumer's ability to demand better, and that needs to be addressed.

We eat too much sugar; doing so conspires against our health, and needs to change. The ends are clear, the best means are less so. I worry that some good intentions could bog us down in conflict that forestalls all progress, distort the relative importance of just one nutrient relative to overall nutrition, and land us on a slippery slope headed toward unintended consequences. The sweet spot will be defined by what works in the real world to improve the quality of prevailing diets, and health.

-fin

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Dr. David L. Katz; www.davidkatzmd.com
www.turnthetidefoundation.org

 

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elcerritan
My bio is not micro
03:31 AM on 02/16/2012
"Even more calamitous pathways could be mapped out for oxygen, which in excess is not just highly toxic, but lethal in rather short order. Oxygen, per se, is not poison of course. The dose makes the poison.

Fallacious argument, Doc. One needs oxygen, at least as a component of the air one breaths. One doesn't need any sugar at all.
03:57 PM on 02/13/2012
Dr. Katz said:

"While the construction of alarming tables and figures demonstrating the calamitous effects of sugar (and specifically, fructose -- Dr. Lustig's particular nemesis) can be defended with legitimate science, it is nonetheless something of a distortion. Even more calamitous pathways could be mapped out for oxygen, which in excess is not just highly toxic, but lethal in rather short order. Oxygen, per se, is not poison of course. The dose makes the poison."

I thought the article was fairly clear that the DOSE of sugar (i.e. the increase in intake of added sugar) was the concern, not simply the presence of sugar. Quite frankly, this is a distortion of the article you are discussion, which most readers do not have access to...fortunately for this argument.

Dr. Katz said:

"Tobacco can be banned outright. Food -- and most ingredients in food -- cannot."

Why not? Why can't HFCS be banned outright? That's what we're talking about here: added sugar. It's ridiculous to make a technically true statement that is false when applied specifically to the subject at hand.

Don't get me wrong: I agree with the efforts to reduce sugar intake, but arguing that someone's premise is a distortion of facts by using distortion of facts is simply hypocritical.
InsultComicDog
I keed... I keed...
02:57 PM on 02/13/2012
I can only speak from my personal experience, and that is that by virtually eliminating all grains, and all sugars, including from fruit, and all starches, and limiting my carbohydrates to just those incidental ones I get from meat, eggs, poultry, fish, offal, and mostly from a few vegetables such as broccoli and Brussels sprouts, I have been able to lose 67 lbs. in 4 1/2 months, I have reduced my a1c from over 13 to below 6, and have reduced my triglycerides, increased my HDL, no longer need to take insulin, Avandia, or statins, and improved blood pressure... and yet, the experts say I'm doing it all wrong. But here's the thing: results matter.
03:59 PM on 02/13/2012
"..­. and yet, the experts say I'm doing it all wrong. But here's the thing: results matter. "

If it makes you feel any better, one of the most recent studies just showed that it doesn't really matter which diet you follow. As long as you reduce your caloric intake, any diet will allow you to loose weight.
07:40 AM on 02/14/2012
That wasn't a recent study. The one you are referring to was done years ago and has been debunked endlessly. The Twinkie diet was a hoax. Nobody measured muscle loss, triglycerides, etc. Careful what you read and who is writing it. Little knowledge can be dangerous.
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Mirabai305
Are you Jeff Vader?
01:11 PM on 02/16/2012
It is quite reasonable that you've lost a ton of weight in short order following that eating plan and it's great that you feel better and your blood sugar is more balanced. However, your statement "results matter" is not entirely complete. You don't seem to be monitoring ~all~ the results. In addition to your HbA1c, you should also be monitoring your cholesterol and all the necessary vitamins and minerals. You were significantly overweight, causing serious health problems. What you want to make sure of is that on your journey to a lower number on the scale you don't create a whole new set of health problems.

You will want to increase your vegetable intake, and probably soon. You don't necessarily have to eat grains or fruits but it does sound like you need more and more varied vegetables. Good luck!
09:46 PM on 02/11/2012
I think the key to a more healthy diet is trying to eat the least amount of processed foods. Cutting those out eliminates many of the harmful additives in our food.
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SmallChange
Tangled Up In Blue!
08:03 AM on 02/14/2012
I totally agree, fanned and faved for being logical with critical thinking skills.
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Mirabai305
Are you Jeff Vader?
01:12 PM on 02/16/2012
Absolutely agree with that. Whole food, local and in season. That's the way to go.
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jzannoni
06:10 AM on 02/11/2012
What continues to amaze me is the lack of communication clarity on the part of most experts regarding the differences in how the various carbohydrates are metabolized by the body. If you track the average per capita consumption of HFCS (High Fructose Corn Syrup) over time since introduction into the food system in the 1970's versus the rate of diabetes and the growth of obesity there is a very close correlation. Purified high concentrations of fructose will have a different impact in the body versus glucose or for that matter sucrose (fructose + glucose). Compare sucrose consumption in other countries where HFCS is not commonly used versus the US. I would like to see this comparison.
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keedyk87
04:02 PM on 02/10/2012
If we banned many harmful products used or produced by the food industry we could prolong the lives of many Americans. This will not happen though as it would affect the PROFITS of the HEALTH INDUSTRY negatively. It is disgusting to me that a country that refers to itself as Christian values the profits of a few more than the health of the many!
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SmallChange
Tangled Up In Blue!
08:06 AM on 02/14/2012
Those values are oxymoronic because most are faux xians belonging to mega lying venues making things up as they go along.
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bmitche
03:44 PM on 02/10/2012
Putting it all in a nutshell, cut back on sugar. There was a time when no one talked about eating too much sugar being a health risk. Now we know.
Autora
No micro-bio for me, thanks
03:17 PM on 02/10/2012
I think we all know that moderation is key, as the Dr. said. What I was shocked and appalled by was learning that other ingredients can be listed first on a label, when we think that means there is less sugar in it, and it isn't true. I imagine that is also the case with fats, now that I am thinking about it. We need to stop this manipulation of public perception-- it's making us sick.
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Mirabai305
Are you Jeff Vader?
01:28 PM on 02/16/2012
It's also the case with monosodium glutamate which has several names you can find on labels, including things like hydrolyzed vegetable protein. And they can list it by its constituent components rather than say MSG. Fun!
Autora
No micro-bio for me, thanks
09:56 PM on 02/16/2012
Sigh, That was an example I didn't even think of. You practically have to be a scientist these days to be sure you know what every ingredient really is. I guess the lesson is to buy only things with the smallest possible number of ingredients, and do most of your own cooking.
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count4eternity
Grace greater than all our sin!
02:37 PM on 02/10/2012
Sugar (and grains, which metabolize just like sugar) might not technically be poison, but it definately feeds poison.
Your colon and GI tract contains "friendly flora." bacteria that keeps the naturally-occuring yeast, (candida albacans) in check. When you take antibiotics, they destroy the good bacteria in your GI tract, allowing the yeast to proliferate, bore holes in your colon (leaky gut syndrome) and attack the rest of your body.

This systemic yeast infection then causes arthritis, diabetes, cancer, and a myriad of other diseases, as well as exascrebating inherited diseases such as MS.

Doctors now realize that sugars fuel inflammation, but most still don't know all that yeast or fungal infections can cause.

See part 2
cwaged1002
There is hope but not for us
02:19 PM on 02/10/2012
All the zealots, whatever their cause, need to get a grip.

The "bottom line," is the only one that matters in American culture, the earth, the water, the very air we breathe is dangerous to our health.

In all things, moderation.
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01:01 PM on 02/10/2012
HFC lobbyist are lobbing in Congress to be able to use the name "Corn Sugar" .
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12:54 PM on 02/10/2012
I say this is propaganda started by the HFC pundits and should be squashed now and forever .
Stop HFC [high fructose corn syrup] , it [HFC] has a long lasting and debilitating effect on the human body , HFC pundits see that the general public have gotten fed up with HFC and weight gain and are now curbing their intake of the HFC goop . HFC pundits can't have that , so attack sugar , ergo the new study and its findings .
Looks just like the Cotton industry assault on Hemp except this time it is the HFC crowd after Sugar .
Make it evil and tax it to make it higher than HFC again [sugar prices have become competitive again against HFC] .
Don't be suckered in by the evil sugar hype , Corn growers and HFC pundits have the most to gain from this . Counter Point !
12:33 PM on 02/10/2012
When I read this article, my first thought was that it could have been written in the PR offices of Coca-Cola. Then, as I read through the comments, I discovered that the author is compromised by his relationship with Hershey's, Nature's Path, Quaker Oats and Eli Lily. What you have here is an excellent example of how the vested interests in both the food and drug industries work to protect their bottom lines. People who, by virtue of their training and academic appointments, are supposed to be objective in their duty to provide health information to the public become compromised by the money that flows from the industries whose number one concern is not your health but their bottom line.
12:33 PM on 02/10/2012
This guy doesn't have enough to do. People that are not busy enough puts thier UNWANTED nose into other peoples business. He has too much money and time, therefore he has to run your life instead of his own. People trying to survive don't bother.
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07:49 PM on 02/11/2012
And the translation is.....................?
11:45 AM on 02/10/2012
And yet the chemicals that are added to our food sources are protected and downplayed. We do not need our food sources to last till armegedon