The PEPFAR Blueprint; the Global Fund's new funding model; the IOM report: all are illustrations of the respective organizations' commitment to the constant evolution required to most effectively save lives.
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JOHANNESBURG, SOUTH AFRICA - JANUARY 27: (SOUTH AFRICA OUT) Sister Sally Naidoo administers an HIV test on a young boy at the Right To Care AIDS clinic on January 27, 2012 in Johannesburg, South Africa. The Right to Care non-governmental organisation has, with US funding from PEPFAR managed to revive their Alexandra based AIDS clinic.The clinic is now providing quality medical treatment to more than 8000 patients. (Photo by Foto24/Gallo Images/Getty Images)
JOHANNESBURG, SOUTH AFRICA - JANUARY 27: (SOUTH AFRICA OUT) Sister Sally Naidoo administers an HIV test on a young boy at the Right To Care AIDS clinic on January 27, 2012 in Johannesburg, South Africa. The Right to Care non-governmental organisation has, with US funding from PEPFAR managed to revive their Alexandra based AIDS clinic.The clinic is now providing quality medical treatment to more than 8000 patients. (Photo by Foto24/Gallo Images/Getty Images)

I love it when a plan comes together. My affection for synchronicity has been well fueled in recent months as a series of global health milestones have converged. Together, these landmarks paint a picture of remarkable alignment between the President's Emergency Plan for AIDS Relief (PEPFAR) and the Global Fund to Fight AIDS, Tuberculosis and Malaria.

At the end of 2012, PEPFAR released its Blueprint for Creating an AIDS-free Generation. More recently, the Global Fund -- the world's largest public health financier -- rolled out its new funding model. Then, on February 20, the Institute of Medicine released its congressionally mandated evaluation of PEPFAR. And just this week, key opinion leaders came together in Washington, D.C. to discuss the IOM report in detail.

This flurry of events makes it clear; it is a time of transformation for global health. The recent announcements also show how complementary the two organizations are as they pursue the same mission: saving lives.

There are several consistent themes within the Blueprint, the new funding model and the IOM report that confirm the alignment between the organizations:

  • Collaboration. One of the explicit action items called out in PEPFAR's Blueprint is strengthened support for the Global Fund. The document states quite clearly that the Global Fund is a critical multilateral vehicle in the fight against the HIV/AIDS pandemic. It also lays out the ways in which the two organizations can most effectively work together to achieve better health outcomes in recipient countries.

In places where the Global Fund and PEPFAR work together, funding models for both organizations are evolving. Resources provided by the bilateral program are focused on building on-the-ground capacity and technical support. As the IOM report indicates, "PEPFAR is gradually shifting funding away from providing services directly to providing technical assistance, building capacity and strengthening systems." The multilateral work, in turn, focuses primarily on providing commodities and other health products.

This approach is highly complementary. For example, both organizations are the primary funders of HIV programs in Tanzania. The Tanzanian government, historically, has used Global Fund financing to supply first-line antiretroviral drugs while PEPFAR's programs provided second-line ARV drugs. However, that is changing. By the end of 2013, Global Fund resources will finance all necessary ARV treatment while PEPFAR will transition to focus exclusively on technical assistance, capacity building, monitoring and evaluation, and voluntary counseling and testing. This new approach is intended to increase effectiveness.

  • Shifting from emergency to sustainability. Both the Global Fund and PEPFAR began as emergency response mechanisms. Today, after more than a decade, both have made strides to become sustainable institutions. This is happening, in part, through a strong focus on supporting recipient countries in ways that allow them to take more ownership for their own public health programs.
  • Just as PEPFAR is helping to increase capacity and strengthen systems on the ground, the Global Fund is also taking the long view. Within the new funding model is a counterpart financing policy in which both a recipient country's ability to invest more of its own funds as well as demonstration of its willingness to do so are evaluated. The idea is to set countries up to, ultimately, be more self sufficient.

  • Augmenting country ownership. The Global Fund is truly a 21st century institution. It has always pursued its mission through a partnership model. With the rollout of the new funding model, this is even more the case today than it was when the organization was conceived of over a decade ago.
  • Through the new model, country and Global Fund representatives, along with civil society and local disease experts, come together from the outset to determine how best to address epidemics on the ground before proposals are sent to the Global Fund Board for consideration. Through these initial conversations, countries will receive feedback on their applications early on in an effort to better set them up for success.

    For its part, PEPFAR, too, collaborates closely with recipient countries and other partners. It has done so throughout its history, resulting in an astonishing scale up of HIV services and programs. It has entered into an era of even closer cooperation with the Global Fund, which includes joint planning and implementation.

  • Targeting resources for impact. The new funding model allows the Global Fund to focus on countries with the highest disease burden and least ability to pay. In other words, it is designed to maximize impact. It takes many of the scientific and epidemiological lessons learned over the past decade and applies them to the fight against HIV/AIDS, tuberculosis and malaria, improving programs for even better results.
  • PEPFAR, too, is achieving greater value-for-money through targeted investments. The Blueprint outlines how the organization is working with partners to achieve a more sustainable response. It is drawing upon national planning processes and using disease-specific strategic investment frameworks along with other tools such as unit-cost benchmarks to design even more effective programs.

    Perhaps the most powerful theme coming out of all of these recent events is "seize the moment." Mark Dybul, Global Fund Executive Director, has repeatedly referenced the unique window of opportunity in which we find ourselves. The scientific advances in global health that enable us to turn the tide on HIV/AIDS, tuberculosis and malaria already exist. But, as the IOM report rightly points out, "we will need to work... to ensure that these hard fought gains are not lost." In other words, we can invest now or we can pay forever.

    The PEPFAR Blueprint; the Global Fund's new funding model; the IOM report: all are illustrations of the respective organizations' commitment to the constant evolution required to most effectively save lives. They are also examples of the remarkable alignment of these two organizations and a rationale for their continued support.

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