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Dr. Harold Koplewicz

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Normal Anxiety, a Disorder, or Both?

Posted: 05/03/10 01:03 PM ET

Earlier this month, The Child Study Center Foundation convened its Scientific Research Council -- a group of world-renowned researchers and clinicians who, in my view, have the unique ability to transform the field of child and adolescent mental health. We sat for two days in a large conference room in Midtown Manhattan, many of the scientists around our table having traveled to the meeting from out of state. We had among us representation from Harvard Medical School; the Yale Child Study Center; the University of Pittsburgh; the University of California, Berkeley; the Oregon National Primate Research Center; and the National Institute of Mental Health (NIMH). Our New York-based colleagues came from the NYU Langone School of Medicine and the NYU Center for Neural Science, as well as from the Nathan S. Kline Institute for Psychiatric Research. Our collective expertise and energy were an inspiration, for never in my 30-year career as a child and adolescent psychiatrist have I had the opportunity to observe the collaboration of such a remarkable team of "superstar" scientists. The group had gathered to finalize an aggressive research agenda that will culminate in new treatments for anxiety disorders in children and adolescents. Early in the meeting, however, several of my colleagues shared their concerns that the public saw neither the importance nor the urgency of studying anxiety disorders in children and adolescents.

"I anticipate the criticism that anxiety isn't important enough," said my colleague Daniel Pine, M.D., of NIMH. "Most people look at anxiety as a trivial problem."

That mind-set is what scientists often worry about when setting research priorities. Our studies need funding and, therefore, must be marketable to funders and to their constituents, the public.

As I listened to Dr. Pine, it was clear to me that the public needed this group to distinguish "normal anxiety" from an "anxiety disorder." I had, in fact, been thinking about this over the past several months. Many friends who aren't in the medical field had looked at me somewhat dumbfounded when I described my plans for collaboration with world-class scientists to develop a research program that could lead to revolutionary treatments for anxiety disorders in children and adolescents. "Why anxiety?" I'd been asked, again and again. Some friends even said, "Anxiety is great," for without it they'd never have been able to accomplish so much in their careers.

So, here I had gathered some of our nation's leading scientists -- and, more than that, secured their leadership on the Scientific Research Council of my new organization, The Child Study Center Foundation -- and their focus on anxiety wasn't really gaining traction. Over the past 15 years, psychiatry has had great success in distinguishing for the public the difference between "depression" and "sadness," but the difference between "worrying" and the kind of "anxieties" categorized in psychiatry's diagnostic manual, DSM-IV, is not well known. We had work to do.

While some anxiety is a normal reaction to stress, the anxiety that interferes with one's ability to function, to handle everyday situations, is a debilitating disorder. Approximately 13 percent of American children and adolescents suffer from an anxiety disorder in a given year. Many of them are unable to leave home or attend school because of this disorder. And consider the broader context: Childhood anxiety disorders are the greatest predictors of mood disorders, chronic depression, and alcohol abuse in adulthood. More than 40 million adults in this country (18 percent of the population) have reported disabling anxiety that negatively impacts their lives. Furthermore, anxiety disorders cost the United States more than $42 billion a year, nearly a third of our nation's mental health bill.

My colleagues and I originally became focused on anxiety disorders because we saw an opportunity to make a very large impact on the lives of millions of children. We believed, and still believe, we could do create this impact in a relatively short amount of time. Childhood anxiety disorders, if left untreated, almost always become chronic, and refractory to treatment in adulthood. This is why we must act now to address this critical issue.

Because our cause is urgent, it is crucial that both scientific and lay communities work toward dispelling the myth that anxiety disorders are somehow less important -- or worse, insignificant -- in the vast landscape of psychiatric illnesses. We're not talking about a normal response to stress here. Anxiety, when it develops into pathology, may be diagnosed as social phobia, separation anxiety, panic disorder, obsessive-compulsive disorder, generalized anxiety disorder, post-traumatic stress disorder, anorexia, and bulimia, among a host of other maladies. We should all be alarmed--very anxious, if you will--when our nation's leading scientists worry that the public's understanding of anxiety stands in the way of groundbreaking research studies.

We need strong public acknowledgment that severe anxiety is the basis for many of the most pervasive psychiatric disorders. And we need a public outcry for research into the stressors that underlie anxiety disorders. This is the only pathway to new and better treatments.

Harold S. Koplewicz, M.D.
President, The Child Study Center Foundation, Inc.
Director, Nathan S. Kline Institute for Psychiatric Research
http://cscfound.org

 
 
 

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Earlier this month, The Child Study Center Foundation convened its Scientific Research Council -- a group of world-renowned researchers and clinicians who, in my view, have the unique ability to trans...
Earlier this month, The Child Study Center Foundation convened its Scientific Research Council -- a group of world-renowned researchers and clinicians who, in my view, have the unique ability to trans...
 
 
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02:31 AM on 05/04/2010
I think there are enough good reasons to be anxious and to not feel guilty about being anxious. I am often at my best when I am anxious. But I do know some of the pitfalls that accompany anxiety. Martin Heidegger seemed to do some work around the idea of anxiety. It will be interesting to see where things go with psychological research as we come to understand processes that we may have misunderstood and/or processes that we lose because we become aware of them...
06:56 AM on 05/04/2010
You obviously misconstrue the difference between low level occasional anxiety everyone experiences and and the debilitating episodes some people are subject to.
08:17 PM on 05/03/2010
Speaking as an adult who has suffered from severe anxiety disorders since I was about 12 years old, I think this research is long overdue and badly needed. Having these types of disorders are a nightmare that never truly goes away, and the only thing that has ever really helped me HAS been drugs from the big, bad EVIL pharma.

It's obvious to me from the comments made thus far that not much has changed since I was a child, either. No one wanted to admit when I was a child that their might be something wrong, and I was left on my own to deal with the hell that was my brain. Sometimes I think that if someone had diagnosed me when I was still a child and worked with me then, I wouldn't need the drugs now.

The attitudes of people toward mental disorders are that we bring them on ourselves: we don't eat right, or we sit on our asses all day and just need to exercise more. If only that were true. I've spent years doing those types of things to try and calm the demons, and nothing but the drugs work.

I am appalled at how people on these blogs are so quick to dismiss someone who may truly want to help children like me as someone who just wants to make a quick buck. That somehow just dismisses what I have gone through my whole life.
01:05 AM on 05/04/2010
You are not alone. It's easy for those that don't understand the severity of anxiety that are so quick to blame the victims of this disorder. I've tried everything natural under the sun, who wants to suffer if it's such an easy fix of exercise and diet?
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vippy
Carpe Diem!
12:48 PM on 05/04/2010
Here in my 60s I have experienced two anxiety attacks, which mimicked a heart attack and I ended up in the hospital being treated for one. After the first one I regognized the symptom and I simply took time out and slept. I noticed that when I was walking uphill I was also short of breath. I listened to the symptoms and I realized that those attacks come on when I took short breaths, I get anxious and my breathing gets shorter. So I figured that every once in a while to take time out and take long deep breaths. I thought my heart rhythm and my breathing were not coinciding, bringing on this attack. Doctor gave me blood pressure pills so the BP quits spiking but I did not want to take these pills for any length of time, so I got me a BP monitor and quickly found out that deep breathing and relaxing also brings down one's BP. I think I have it under control now, putting aside any thoughts that occupy too much time and work me up into a frenzy.
05:46 PM on 05/03/2010
Let's start talking to our kids, feeding them well, giving them vitamins. This whole "research into anxiety" is simply a prelude to and excuse for selling more psychiatric drugs. If we keep this up we will have no creativity, no spark and no life in our future generations. Greed and control are powerful motivations for these people and they must be stopped.

To get the real information, please take a look at the website of Citizen's Commission on Human Rights (CCHR.org).
06:58 AM on 05/04/2010
There is absolutely zero evidence for correlation between vitamins and good food and prevention of the anxiety disorder. Become educated on the subject before posting.
03:22 PM on 05/04/2010
Vitamins cannot get rid of or prevent anxiety. Instead of just blaming everything on the "evil pharma" how about we actually learn more about anxiety disorders which many people deal with daily.
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scarletxoxoxo
I was born in a ditch and I eat babies.
04:47 PM on 05/03/2010
Maybe those kids need more understanding and sympathy from adults.
05:34 PM on 05/03/2010
Isn't a little sympathy and understanding what we all need?
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organicconnect
03:21 PM on 05/03/2010
I believe the idea of a "vast landscape" of psychiatric illnesses in children is a prelude to a pharmacological nightmare. The emotional health of children will never be handled with drugs and never be cared for by a profession which openly states it cannot diagnose or cure mental illness. This abject failure of a profession has led to BigPharma living in the wallets of concerned parents. We need to campaign to keep psychiatric interests away from our children with the same ferocity we would attach to any other type of predator. The "vast landscape" of mental problems in children in most cases is a narrow landscape of simple factors like nutrition. http://organicconnectmag.com/wp/2007/10/adhd-is-drugging-our-children-the-answer/
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Pansey
California transplant living in the South
03:26 PM on 05/03/2010
Good post. Nutrition and good parenting goes a long way in raising stable children. What ever happened to good old 'common sense' in guiding children through their childhood?
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sandalwood
songs of the shamans...
05:28 PM on 05/03/2010
Excellent post!