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Joel Fuhrman, M.D.

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GOMBBS: Greens, Onions, Mushrooms, Berries, Beans and Seeds

Posted: 10/ 9/2011 8:24 am

"GOMBBS" is an acronym you can use to remember the most nutrient-dense, health-promoting foods on the planet. These are the foods you should eat every day, and they should make up a significant proportion of your diet -- these foods can be effective at preventing chronic disease and promoting health and longevity.

G -- Greens

Raw leafy greens contain only about 100 calories per pound and are packed with nutrients. Leafy greens contain substances that protect blood vessels and are associated with reduced risk of diabetes.1 Greens are an excellent tool for weight loss, since they can be consumed in virtually unlimited quantities. Leafy greens are also the most nutrient-dense of all foods, but unfortunately are only consumed in miniscule amounts in a typical American diet.

We should follow the example of our closest living relatives -- chimpanzees and gorillas -- who consume tens of pounds of green leaves every day. The majority of calories in green vegetables, including leafy greens, come from protein, and this plant protein is packaged with beneficial phytochemicals: Green vegetables are rich in folate (the natural form of folic acid), calcium and contain small amounts of omega-3 fatty acids. Leafy greens are also rich in antioxidant pigments called carotenoids, specifically lutein and zeaxanthin, which are the carotenoids known to promote healthy vision.2

Also, several leafy greens and other green vegetables (such as bok choy, broccoli and kale) belong to the cruciferous family of vegetables. Vegetables contain protective micronutrients and phytochemicals, but cruciferous vegetables have a unique chemical composition. They contain glucosinolates, and when their cell walls are broken by blending, chopping or chewing, a chemical reaction converts glucosinolates to isothiocyanates (ITCs) -- compounds with a variety of potential anti-cancer effects. Because different ITCs can work in different locations in the cell and on different molecules, they can have combined additive effects, working synergistically to remove carcinogens, reduce inflammation, neutralize oxidative stress, inhibit angiogenesis (the process by which tumors acquire a blood supply) and help kill cancer cells.3

O -- Onions

Onions, along with leeks, garlic, shallots and scallions, make up the allium family of vegetables, which can have beneficial effects on the cardiovascular and immune systems, as well as posible anti-diabetic and anti-cancer effects. Allium vegetables are known for their characteristic organosulfur compounds. Similar to the ITCs in cruciferous vegetables, organosulfur compounds are released when onions are chopped, crushed or chewed. Epidemiological studies have suggested that increased consumption of allium vegetables is associated with lower risk of gastric and prostate cancers. It's been said these compounds prevent the development of cancers by detoxifying carcinogens, halting cancer cell growth and blocking angiogenesis.4

Onions also contain high concentrations of health-promoting flavonoid antioxidants, predominantly quercetin, and red onions also contain at least 25 different anthocyanins.5,6 Quercetin has been shown to slow tumor development, suppress growth and proliferation and induce cell death in colon cancer cells.7 Flavonoids also have anti-inflammatory effects that may contribute to cancer prevention.8

M -- Mushrooms

Consuming mushrooms regularly has been associated with decreased risk of breast, stomach and colorectal cancers. In one recent Chinese study, women who ate at least 10 grams of fresh mushrooms each day (about one mushroom per day) had a 64 percent decreased risk of breast cancer. Even more dramatic protection was gained by women who ate 10 grams of mushrooms and drank green tea daily -- an 89 percent decrease in risk for premenopausal women, and 82 percent for postmenopausal women.9,10

White, cremini, Portobello, oyster, shiitake, maitake and reishi mushrooms all have anti-cancer properties -- some have been shown to be anti-inflammatory, stimulate the immune system, prevent DNA damage, slow cancer cell growth, cause programmed cancer cell death and inhibit angiogenesis. In addition to these properties, mushrooms are unique in that they contain aromatase inhibitors -- compounds that can block the production of estrogen. These compounds are thought to be largely responsible for the preventive effects of mushrooms against breast cancer -- in fact, there are aromatase-inhibiting drugs on the market that are used to treat breast cancer. Regular consumption of dietary aromatase inhibitors is an excellent strategy for prevention, and it's been shown even the most commonly eaten mushrooms (white, cremini and Portobello) have a high anti-aromatase activity.11

B -- Berries

Blueberries, strawberries and blackberries are true super foods. Naturally sweet and juicy, berries are low in sugar and high in nutrients -- they are among the best foods you can eat. Their vibrant colors mean that they are full of antioxidants, including flavonoids and antioxidant vitamins -- berries are some of the highest antioxidant foods in existence. Berries' plentiful antioxidant content confers both cardioprotective and anti-cancer effects, such as reducing blood pressure, reducing inflammation, preventing DNA damage, inhibiting tumor angiogenesis and stimulating of the body's own antioxidant enzymes. Berry consumption has been linked to reduced risk of diabetes, cancers and cognitive decline.12 Berries are an excellent food for the brain -- berry consumption has been shown to improve both motor coordination and memory. 13

B -- Beans

Beans (and other legumes, as well) are a powerhouse of superior nutrition and the most nutrient-dense carbohydrate source. They can act as an anti-diabetes and weight-loss food because they are digested slowly, having a stabilizing effect on blood sugar, which promotes satiety and helps to prevent food cravings. Plus, they contain soluble fiber, which has been shown to lower cholesterol levels.14 Beans are unique foods because of their very high levels of fiber and resistant starch, carbohydrates that are not broken down by digestive enzymes. Fiber and resistant starch not only reduce total the number of calories absorbed from beans but are also fermented by intestinal bacteria into fatty acids that can help to prevent colon cancer.15 Eating beans, peas or lentils at least twice a week has been found to decrease colon cancer risk by 50 percent.16 Legume intake can also provide protection against oral, larynx, pharynx, stomach and kidney cancers.17

S -- Seeds

Nuts and seeds contain healthy fats and are rich in a spectrum of micronutrients including phytosterols, minerals and antioxidants. Countless studies have demonstrated the cardiovascular benefits of nuts, and including nuts in the diet can help aid in weight maintenance and diabetes prevention. 18,19

The nutritional profiles of seeds are similar to nuts when it comes to healthy fats, minerals and antioxidants, but seeds are also abundant in trace minerals, higher in protein than nuts, and each kind of seed is nutritionally unique. Flax, chia and hemp seeds are extremely rich sources of omega-3 fats. In addition to the omega-3s, flaxseeds are rich in fiber and lignans. Flaxseed consumption has been shown to protect against heart disease by a number of different mechanisms, and lignans, which are present in both flaxseeds and sesame seeds, can have anti-cancer effects.20

Sunflower seeds are especially rich in protein and minerals. Pumpkin seeds are rich in iron and calcium and are a good source of zinc. Sesame seeds have the greatest amount of calcium of any food in the world and provide abundant amounts of vitamin E. Also, black sesame seeds are extremely rich in antioxidants.21 The healthy fats in seeds and nuts also aid in the absorption of nutrients when eaten with vegetables.

You can learn more about the health benefits of GOMBBS in my new book "Super Immunity," a guide to naturally strengthening the immune system against everything from the common cold to cancer.

Dr. Fuhrman is a New York Times best-selling author, nutritional researcher and board certified family physician specializing in nutritional medicine. Learn more by visiting his informative website at DrFuhrman.com and his blog at Diseaseproof.com, and following Dr. Fuhrman on Facebook and Twitter.

References:

1. Carter P, Gray LJ, Troughton J, et al. Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis. BMJ. 2010 Aug 18;341:c4229.
Journal of Clinical Investigation (2011, March 24).

High levels of dietary nitrate might in part explain the vascular benefits of diets rich in leafy greens. ScienceDaily. Retrieved March 30, 2011.

2. Stringham JM, Bovier ER, Wong JC, Hammond BR Jr. The influence of dietary lutein and zeaxanthin on visual performance. J Food Sci. 2010 Jan-Feb;75(1):R24-9.

3. Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacol Res. 2007 Mar;55(3):224-36.

Cavell BE, Syed Alwi SS, Donlevy A, et al., Anti-angiogenic effects of dietary isothiocyanates: mechanisms of action and implications for human health. Biochem. Pharmacol., 2011. 81(3): p. 327-36.

4. Powolny AA, Singh SV. Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds. Cancer Lett. 2008 Oct 8;269(2):305-14.

5. Pierini R, Gee JM, Belshaw NJ, et al. Flavonoids and intestinal cancers. Br J Nutr. 2008 May;99 E Suppl 1:ES53-9.

6. Slimestad R, Fossen T, VÃ¥gen IM. Onions: a source of unique dietary flavonoids. J Agric Food Chem. 2007 Dec 12;55(25):10067-80.

7. Miyamoto S, Yasui Y, Ohigashi H, et al. Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice. Chem Biol Interact. 2010 Jan 27;183(2):276-83.

Shan BE, Wang MX, Li RQ. Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway. Cancer Invest. 2009 Jul;27(6):604-12.

Xavier CP, Lima CF, Preto A, et al. Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells. Cancer Lett. 2009 Aug 28;281(2):162-70.

8. Ravasco P, Aranha MM, Borralho PM, et al. Colorectal cancer: Can nutrients modulate NF-kappaB and apoptosis? Clin Nutr. 2010 Feb;29(1):42-46.

9. Hong SA, Kim K, Nam SJ, et al: A case-control study on the dietary intake of mushrooms and breast cancer risk among Korean women. Int J Cancer 2008, 122:919-923.

Shin A, Kim J, Lim SY, et al: Dietary mushroom intake and the risk of breast cancer based on hormone receptor status. Nutr Cancer 2010, 62:476-483.

Zhang M, Huang J, Xie X, et al: Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women. Int J Cancer 2009, 124:1404-1408.

10. Hara M, Hanaoka T, Kobayashi M, et al: Cruciferous vegetables, mushrooms, and gastrointestinal cancer risks in a multicenter, hospital-based case-control study in Japan. Nutr Cancer 2003, 46:138-147.

11. Chen S, Oh SR, Phung S, et al: Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus). Cancer Res 2006, 66:12026-12034.

12. Bazzano LA, Li TY, Joshipura KJ, Hu FB. Intake of fruit, vegetables, and fruit juices and risk of diabetes in women. Diabetes Care. 2008 Jul;31(7):1311-7.

Hannum SM. Potential impact of strawberries on human health: a review of the science. Crit Rev Food Sci Nutr. 2004;44(1):1-17.

Joseph JA, Shukitt-Hale B, Willis LM. Grape juice, berries, and walnuts affect brain aging and behavior. J Nutr. 2009 Sep;139(9):1813S-7S.

Stoner GD, Wang LS, Casto BC. Laboratory and clinical studies of cancer chemoprevention by antioxidants in berries. Carcinogenesis. 2008 Sep;29(9):1665-74.

Cassidy A, O'Reilly EJ, Kay C, et al: Habitual intake of flavonoid subclasses and incident hypertension in adults. Am J Clin Nutr 2011, 93:338-347.

Roy S, Khanna S, Alessio HM, et al: Anti-angiogenic property of edible berries. Free Radic Res 2002, 36:1023-1031.

13. Bickford PC, Shukitt-Hale B, Joseph J. Effects of aging on cerebellar noradrenergic function and motor learning: nutritional interventions. Mech Ageing Dev. 1999 Nov;111(2-3):141-54.

Krikorian R, Shidler MD, Nash TA, et al. Blueberry supplementation improves memory in older adults. J Agric Food Chem. 2010 Apr 14;58(7):3996-4000.

14. Bazzano LA, Thompson AM, Tees MT, et al. Non-soy legume consumption lowers cholesterol levels: A meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis 2011 Feb;21(2):94-103.

Aune D, De Stefani E, Ronco A, et al. Legume intake and the risk of cancer: a multisite case-control study in Uruguay. Cancer Causes Control. 2009 Nov;20(9):1605-15.

15. O'Keefe SJ, Ou J, Aufreiter S, et al. Products of the colonic microbiota mediate the effects of diet on colon cancer risk. J Nutr. 2009 Nov;139(11):2044-8.

16. Singh PN, Fraser GE. Dietary risk factors for colon cancer in a low-risk population. Am J Epidemiol. 1998 Oct 15;148(8):761-74.

17. Aune D, De Stefani E, Ronco A, et al. Legume intake and the risk of cancer: a multisite case-control study in Uruguay. Cancer Causes Control. 2009 Nov;20(9):1605-15.

18. Nash SD, Nash DT. Nuts as part of a healthy cardiovascular diet. Curr Atheroscler Rep. 2008 Dec;10(6):529-35.

Sabaté J, Ang Y. Nuts and health outcomes: new epidemiologic evidence. Am J Clin Nutr. 2009 May;89(5):1643S-1648S.

Mattes RD et al. Impact of peanuts and tree nuts on body weight and healthy weight loss in adults. J Nutr. 2008 Sep;138(9):1741S-1745S.

Natoli S, McCoy P. A review of the evidence: nuts and body weight. Asia Pac J Clin Nutr. 2007;16(4):588-97

19. Kendall CW, Josse AR, Esfahani A, Jenkins DJ. Nuts, metabolic syndrome and diabetes. Br J Nutr. 2010 Aug;104(4):465-73.

20. Bassett CM, Rodriguez-Leyva D, Pierce GN. Experimental and clinical research findings on the cardiovascular benefits of consuming flaxseed. Appl Physiol Nutr Metab. 2009 Oct;34(5):965-74.

Webb AL, McCullough ML. Dietary lignans: potential role in cancer prevention. Nutr Cancer. 2005;51(2):117-31.

Saarinen NM, Wärri A, Airio M, et al. Role of dietary lignans in the reduction of breast cancer risk. Mol Nutr Food Res. 2007 Jul;51(7):857-66.

Coulman KD, Liu Z, Hum WQ, et al. Whole sesame seed is as rich a source of mammalian lignan precursors as whole flaxseed. Nutr Cancer. 2005;52(2):156-65.

21. Shahidi F, Liyana-Pathirana CM, Wall DS. Antioxidant activity of white and black sesame seeds and their hull fractions. Food Chemistry 2006;99(3): 478-483.

 
 
 

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"GOMBBS" is an acronym you can use to remember the most nutrient-dense, health-promoting foods on the planet. These are the foods you should eat every day, and they should make up a significant propor...
"GOMBBS" is an acronym you can use to remember the most nutrient-dense, health-promoting foods on the planet. These are the foods you should eat every day, and they should make up a significant propor...
 
 
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12:06 AM on 12/07/2011
Watching him on IPBS! He's brilliant! Why don't ALL American doctors say these things this way? I love it! Our bodies HAVE the ability to fight diseases, we just have to put in the phytonutrient-antioxidant-drenched fuel so it can do it! I will go restock my GOOMBS tomorrow. All already are among my fav foods! Cutting out sugars (fake & refined) & animal meats. (Not going vegan but will drastically reduce my meat-based meals!) Gonna make me some Mushroom, Garlic, Onion, Bean & Spinach dish & sprinkle it w/herbs & my Dr. Oz Tumeric/Blk Pepper shaker mix(that I add Cayenne, Cumin, & Paprika to)! Be gone Free Radicals! :D
11:10 AM on 10/24/2011
One food not mentioned in Dr. Fuhrman's article that is mentioned in his book Super Immunity is pomegranates. And since they are in season, consider buying them in bulk when on sale and freezing the seeds!
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HUFFPOST SUPER USER
Chuck Bluestein
Always searching for latest health breakthrough
06:58 PM on 10/14/2011
Great article but Dr Fuhrman is a living legend! On Youtube there is a video with Dr Oz introducing Dr Fuhrman as the expert on eating and staying thin. He is the country's leading expert on fasting. He created the nutritarian diet of eating nutrient dense foods. The chain of Whole Foods stores uses his ANDI scale (aggregate nutrient density index).

Also besides what he mention about fungus (mushrooms are fungus or fungi) cordyceps mushrooms are also good at fighting cancer and helping the immune system to recognize tumors. As far as berries there are a lot of studies that show that berries are the best foods for cardiovascular health. http://bit.ly/bGcKcG Don't forget about the super food berries like wolfberries and the acai berries. So that covers the 3 leading causes of death-- heart attacks, cancer and strokes.
02:22 PM on 10/13/2011
The Incredible Onion and Its Medicinal Benefits
Onions are used just about everywhere from hot dogs, hamburgers, tacos and untold salads yet some won't come near them because of their pungent odor or how it leaves their breath once ingested.
http://www.articlesbase.com/nutrition-articles/the-incredible-onion-and-its-medicinal-benefits-5227297.html
05:50 PM on 10/10/2011
MBBS are the qualifications for a doctor in many parts of the world. It mean Bachelor of Science and Bachelor of Medicine. So very appropriate.
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SteveC 1979
Just...don't.
03:42 PM on 10/10/2011
Interesting article. As a side note, it always amazes me that in most article like this, animal products are never mentioned.
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Z trufflesniffer
My Micro-bio is still empty
10:32 PM on 10/10/2011
Dr. Fuhrman advocates a plant based diet with no dairy products OR meat of any kind.
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HUFFPOST SUPER USER
Chuck Bluestein
Always searching for latest health breakthrough
07:07 PM on 10/14/2011
There are thousands of phytochemicals that are great for health like allicin in garlic, lycopene in tomatoes, resveratrol in grapes and wine and curcumin in tumeric. Dr Fuhrman counts these in his ANDI scale of foods. But phytochemicals are only in plant foods. Huffington Post had an article about cherries being better for pain than aspirin. You can find lots of articles like this about plant foods. But dead animals taste good but are not that healthy. Bill Clinton did not become a vegan because he did not like meat. He had a stent put in and was concerned about dying.
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henriette and hube
my goal is to live each day
02:48 PM on 10/10/2011
Excellent reminder of the foods we SHOULD eat. My copy of Super Immunity is on its way.
11:02 AM on 10/10/2011
I love it, "We should follow the example of our closest living relatives -- chimpanzees and gorillas -- who consume tens of pounds of green leaves every day." That right there would be a health promoting and weight controlling bonanza for each and every one of us. I'm always amazed how we turn our nose up at greens. I eat a ton, but no where near 10 lbs. Looks like I've got a new goal. I've got kale, collards and chard all teaming in my garden. Time to give the Vitamix a whirl to get a jump on this before lunch! Thanks for the inspiration, healthy eating is always a mission of mine as you can see from my 'take' on the vitamin and supplement 'dietary bypass' question http://www.drbaileyskincare.com/blog/vitamins-for-healthy-skin/ ,but 10lbs of greens a day, I'm still pondering what that would feel like.
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henriette and hube
my goal is to live each day
02:51 PM on 10/10/2011
Just looks at the size of the guys who are eating 10 lbs of greens a day and you won't feel so bad.
I eat a lot of greens as well. I had spinach and kale in my smoothie this morning and having a spinach salad for lunch.

Nice that you can grow them.
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HUFFPOST SUPER USER
Chuck Bluestein
Always searching for latest health breakthrough
07:14 PM on 10/14/2011
No, he means that greens are very important to your diet but not that you should eat the same amount of greens as a 400 pound gorilla eats! Unless you weigh 400 pounds and then you need it.
08:48 AM on 10/10/2011
There are three things you will always find in my fridge...mushrooms, greens and onions. I eat these everyday.

I believe/worship in the power of an onion. My dad has always eaten an onion like you eat an apple. And has never been sick a day in his life. Worked until he was 75 years of age and is still kicking at 78. Gets around better than some of my friends. Walks about 4 miles everyday. 1st time he ever went to a doctor was 7 years ago (because we made him), doc told him he has the heart of a 32 year old very healthy male. During that visit, he was given a prostate exam..found cancer, removed it. No treatment needed....doc said it was the onion a day.
12:19 AM on 10/10/2011
I had assumed that the "B" was for bacon, but I was way off.

Seriously though, I wonder why garlic wasn't included. Sure, you can't include everything, but I've read no end of good things about garlic and it seems a natural if you're also mentioning onions.
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henriette and hube
my goal is to live each day
02:55 PM on 10/10/2011
I think you just missed garlic. It's included in the first sentence under O. I have Eat to Live so know he's a huge proponent of the heavenly garlic. I love red garlic!
02:42 PM on 10/11/2011
Ah, I see, thanks. There are so many of these articles and they often pick out this or that fruit or vegetable almost at random that I guess I've begun to just skim these articles too fast.
09:59 PM on 10/09/2011
Hey, it works for me!
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09:45 PM on 10/09/2011
I love all those! We're having spaghetti with garlic and mushrooms tonight with berries on frozen yogurt for dessert. Last night we had bean burritos with lettuce, tomatoes, avocado, and salsa sprinkled with sunflower seeds. So good!
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henriette and hube
my goal is to live each day
02:56 PM on 10/10/2011
Me too, nothing better than pasta with garlic and mushrooms and a lovely salad. One of my favorite dishes.
04:33 PM on 10/09/2011
You're making me hungry.
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lele23
04:28 PM on 10/09/2011
Thanks, Dr. Fuhrman. Very informative!
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HUFFPOST SUPER USER
frank day
Obama cares about all of U.S.
02:39 PM on 10/09/2011
Wow! That just rolls off the tongue.

What was it again?