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Keith I. Block, M.D.

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Preventing a Recurrence of Cancer

Posted: 08/04/10 08:00 AM ET

According to the National Cancer Institute, there are over 12 million cancer survivors in the U.S. today. And that number is expected to grow as the population ages, treatments improve and tests find the disease earlier.

Cancer survivors face a myriad of health challenges, not to mention the daunting fear the cancer will return. However, once a patient is deemed "in remission," they are typically disconnected from care -- as well as any attending support -- and told to come back in three to six months where diagnostic scans or blood tests will determine if the cancer has returned.

We suggest a far more pro-active, empowered approach: a remission maintenance plan that offers cancer survivors a personalized program to regain control of their health, restore vitality and protect against the cancer returning. At the Block Center, once a patient has completed their treatment, we personally tailor a comprehensive remission maintenance program for them that includes: therapeutic nutrition, exercise, mind-spirit care and anti-tumor therapies.

Understandably, after hearing that they are "in remission," patients may want to retreat psychologically to a "cancer-free" zone and never think about the disease again. But this is why they shouldn't: Cancer is as much a microscopic and molecular disease as it is a visible one. Thus, a patient in remission may still harbor malignant cells (ones that were resistant to chemotherapy or radiation and therefore survived the attack phase). These cells unfortunately have the ability to show up with a vengeance, even when one least suspects. Not placing far greater emphasis on containing and addressing these cells from the get-go is a significant omission of mainstream treatment. But while preemptive treatment strategies may only exist in integrative clinics, when it comes to the diagnostic side, a new technology has begun demonstrating the relevance of these virulent escape cells.

Enter CTCs (circulating tumor cells)! Over a decade ago, the Block Center was one of a few that were performing bone marrow biopsies to evaluate for malignant cells in both the marrow and in circulation. It took several years, but eventually this evolving diagnostic technology made it into conventional care. While easier to perform today and more reliable as well, we continue to use this in our clinic. This technology allows us and others the ability to measure in our patients the number of these detached cells circulating freely from the main cancer mass. Though not yet approved for all cancer, research studies have shown that an increase of these cells is prognostic of a patient's survival.

For instance, a CTC count may be a better prognostic indicator for survival among prostate cancer patients than a PSA level -- the test used presently to determine and follow the course of prostate cancer growth.

By comparing the levels of CTC in 37 men with metastatic prostate cancer, researchers at Thomas Jefferson University found that for the men with 5 CTCs or more, the median overall survival was only 8.4 months. Whereas, if these men were found to have less than 5 CTCs, the median survival was 48 months!

The relevance of CTCs is also relevant to other cancers. For instance, CTCs were measured in 151 women with metastatic breast cancer. The MD Anderson Cancer Center's researchers found that those patients with five or more CTCs had a median survival of only 13 months, whereas those with less five survived over 29 months!

Controlling, preventing or overcoming these detached and disseminating cells is possibly the biggest conundrum facing cancer scientists. While these cells are generally addressed during treatment, the first steps of recurrence prevention should start with strategies to counter the survival of these residual cells and inhibiting their potential proliferation. In fact, CTCs that have gone through the onslaught of treatment and have nonetheless survived have the potential to evolve into more aggressive clones encouraging a more virulent malignancy. So what to do?

Aggressive Monitoring

We recommend regular monitoring of patients' status with lab tests and imaging to detect early signs of disrupted biochemistry or a recurrence of disease, especially in the year or two after remission.

Being "diagnostically aggressive" may allow us to be less invasive therapeutically. In the first years after remission, therefore, we recommend:

1. Clinical visits with your oncologist, at least every three to four months in the first and second year and every six months for the next several years

2. Scans and blood tests of tumor markers every three months.

3. Complete blood count and chemistry test every three months.

4. Nutrition status, including weight changes, body composition and albumin levels, every three months.

5. Internal terrain monitoring every three to six months for the terrain factors that are most problematic.

While monitoring, there is no reason to wait anxiously for the other shoe to drop. So immediately implement a full integrative program.

1. Make sound dietary changes toward adherence of a whole foods diet. Reduction in dietary fat has already been shown to cut recurrences in different cancers. Controlling refined flour, sugar and junk food is a necessary step to avoid the recurrence risk of elevated blood glucose and spiking insulin levels.

2. Introduce aerobics, strength and flexibility training into your daily schedule. Yoga, pilates, chi gong or any number of fitness approaches is an essential step towards recurrence prevention. Considerable research supports that risk, response, recurrence and outcomes are tied to physical care.

3. Mitigate stress through progressive relaxation, meditation or simply easing the load on an excessive work schedule. Elevated cortisol levels are associated with poorer outcomes in breast cancer patients. So do what it takes to transform less healthy patterns.

4. Get rest and adequate sleep. The more active you are in the daytime, the better you'll sleep at night. Few of us get enough sleep and the adverse consequences to an otherwise health promoting, cancer inhibitory environment can be devastating.

 
According to the National Cancer Institute, there are over 12 million cancer survivors in the U.S. today. And that number is expected to grow as the population ages, treatments improve and tests find...
According to the National Cancer Institute, there are over 12 million cancer survivors in the U.S. today. And that number is expected to grow as the population ages, treatments improve and tests find...
 
 
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02:43 PM on 08/08/2010
My husband was diagnosed with cancer of unknown primary site 5 1/2 yrs ago and was told that palliative chemo was his only choice. Fortunately, we explored other options, which included a trip to The Block Medical Center. He was in remission for 2 1/2 yrs, but has had several recurrences since. However, his quality of life at this point is great and we continue to follow Dr. Keith Block's recommendations. We are always seeking!
05:29 PM on 08/06/2010
One thing that I did that is a little different than the norm is that I didn't ask ANY questions. I never Goggled my cancer. I never asked my doctor what to expect. Never asked how long I had (I was stage 4 when diagnosed). I figured that my "little professor.
http://health-actuary.blogspot.com/
10:28 AM on 08/06/2010
I'd like to see a study on how many women who developed breast cancer were getting a divorce.
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megwolff
Plant-based cook & survivor
06:02 PM on 08/04/2010
Articles like this are why I LOVE reading the Huffington Post! Being pro-active is the only way. Why wait around hoping and praying when their is actually a LOT we CAN DO?! Dr. Block's article makes SO much sense.

I was also diagnosed with invasive stage 3b breast cancer (several years after loosing a leg to bone cancer), had conventional treatment, but was still told by my doctors that the breast cancer would most likely recurr within a year in the same area. It's been 12 years and I remain cancer-free. I attribute my remission to changing to a sound whole foods way of eating similar to what Dr. Block recommends.

As time passed I met many others (breast & other cancers) who have extended their lives by dietary and lifestyle changes and I've documented their journeys. If you are considering this approach and need some inspiration: http://www.megwolff.com/survivors.html

It takes twenty years to change the status quo, why wait?
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f0rTyLeGz
Everything is falling.
03:00 PM on 08/04/2010
Im a cancer survivor... 4.5 years. I have no advice for anyone. I did chemotherapy, and then Rituxan every six months for two years.

One thing that I did that is a little different than the norm is that I didn't ask ANY questions. I never Goggled my cancer. I never asked my doctor what to expect. Never asked how long I had (I was stage 4 when diagnosed). I figured that my "little professor" (do people still use that term?) would drive me crazy if I tried to become an authority on my cancer. I left all that up to my doctors, and friends and relatives... and I told everyone my approach that I wasn't interested in finding out details about my cancer... especially new or alternative treatments.
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silverstreet
All you need is love
03:26 PM on 08/04/2010
I too am a cancer survivor....stage 4 when diagnosed. My doctor said, "Don't talk about your cancer with anyone except close friends and family"--which was the best advice I received. I trusted my doctor completely. Four years cancer free. But I still worry if or when it will come back -- and if my health insurance will pay for the treatment i need -- that's my biggest worry. (The trend is that Health insurance companies are not paying 100% of chemotherapy anymore)
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f0rTyLeGz
Everything is falling.
05:18 PM on 08/04/2010
Glad to hear you are doing well!

Paying the medical bills couldn't have been more stressful. It was humbling, and embarrassing. It went on for years.

I showed up there after losing a quarter of my weight in three weeks, and I could not have been weaker... soon I find myself in a conversation about my NET worth. And I know that somewhere, maybe right there in the hospital, there really is a Death Panel deciding on whether or not my life is worth the time and money it will cost them to keep me going.
11:01 AM on 08/04/2010
A lot of cancers aren't really in gone but managed. They can prolong life with cancer but whether it's cured or not is probably difficult to prove. Usually they call it "undetectable" but it doesn't mean it's not there merely being managed waiting to gain strength and come back.
07:48 PM on 08/04/2010
Pretty much the case. Fundamentally, cancer starts with a messed up message associated with cell reproduction. The potential for such a mess up remains and grows ever greater as the body ages. It is even conceivable that aging itself is a form of cancer - thinking outside the box here. I believe that a positive view of life, regardless of whether cancer hits or not, is going to help. May as well use the years available for you to do some good.
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LaurieAnn
Wake Up! Grow Up! Lighten Up!
11:01 AM on 08/04/2010
As a cancer survivor myself I am finding that the most helpful thing for me personally is to focus on the last four items on the list: diet, exercise, stress and sleep as well as my relationship with myself and those I love while I let the cancer cells do whatever they are going to do. I want to do what is in my power to have the best life while I recognize that beyond taking care of myself I have no control over whether or not the cancer returns.
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Alison Rose Levy
Connect the Dots www.healthjournalist.com
10:49 AM on 08/04/2010
Please check out my article “Making the World Safe for Cancer,†http://www.huffingtonpost.com/alison-rose-levy/health-cancer-making-the_b_567424.html which looks at some of the reasons cancer rates are rising.
01:37 PM on 08/04/2010
Why are the comments closed on your article, particularly if you are going around to other posts and self-advertising? You don't want criticism from people who actually understand cancer, and don't agree with your conspiracy theories?
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f0rTyLeGz
Everything is falling.
02:25 PM on 08/04/2010
Urban Zen!? What a world.
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awarg
10:39 AM on 08/04/2010
Apositive mind can get you through the chemo and radiation part . But as far as having cancer, itself, I know this isn't true. Cancer strikes when and where it can. My father lived through chemo and was cancer free for 30 years, then it came back. He never changed his diet or thoughts of recovery from cancer. It's the luck of the draw. One thing I did learn from him- never believe what a doctor tells you- my dad was given 6 mon. to live! He always told me to make liars out of the med. professionials!
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drumz
Those little red panties they pass the test
07:33 PM on 08/05/2010
A good movie that has this in the theme was on the other night; The Bumblebee Flies Anyway with Elijah Wood. Great suspenseful movie http://www.amazon.com/The-Bumblebee-Flies-Anyway/dp/B0007WIVLQ/ref=sr_1_1?s=dvd&ie=UTF8&qid=1281051028&sr=1-1
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awarg
09:36 AM on 08/06/2010
Thanks , drumz, for telling me bout the film. I'd like to see it. Whwn my dad was in chemo, he he would see 5 regulars. He was the only one to survive past 1 year- they all had hope and faith towards recovery.
ThatsTheTheWayItIs
religion, ideology, partisanship are delusional
10:12 AM on 08/04/2010
Research has shown that "mind-spirit care" does not help fight cancer.

Studies compared cancer patients who were given counseling on keeping a "positive attitude", to those who received no such training.

The outcomes were the same; a positive attitude does not help cure cancer.

Many patients who were part of the "positive attitude" group were relieved to find it had no effect, because they felt guilty that they didn't do enough. And no wonder: they have cancer, so they feel bad, then they feel guilty about feeling bad, think they are hurting their chances of recovery.

A positive attitude does not cure cancer, and I doubt it prevents it.
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LaurieAnn
Wake Up! Grow Up! Lighten Up!
10:55 AM on 08/04/2010
I think that being real with whatever a person is facing is far more helpful than trying to maintain a positive outlook that isn't real. That said however, I do think that one can act in health positive ways such as the last four items listed even when one is feeling fearful. This is what I'm practicing in my cancer recovery program.
ThatsTheTheWayItIs
religion, ideology, partisanship are delusional
11:30 AM on 08/04/2010
Sure, every thing else he suggests is good advice.

I would also take turmeric (curcumin), which I already do; Google "curcumin cancer" for info.

And marijuana not only helps with the symptoms, but research shows THC kills cancer cells, and may well inhibit or cure cancer, not to mention MS, Alzheimer. Read about in Science News, an excellent periodical I've subscribed to for 30+ years:

http://www.sciencenews.org/index/access/activity/view/id/59965/title/Pot_Rx_The_promise_of_medicinal_marijuana
01:50 PM on 08/04/2010
The only thing that kept me going through cancer therapy was maintaining a positively "pissed-off" attitude and doing enough research to keep my practicing physicians relatively honest.
09:21 AM on 08/04/2010
First, you must avoid sugar! You must avoid processed fats/oils. Eat raw fats. Eat a mostly raw diet. Take a tablespoon of baking soda daily. Meditate a lot. A silent mind eases stress, which minimizes all the harmful actions the 'fight or flight' response creates. Consciously KNOW that you will beat the cancer and you will. This has been show to be true in controlled studies.
10:15 AM on 08/04/2010
Citation, please (for the "controlled study").
11:03 AM on 08/04/2010
There are studies that prove cutting out sugar and animal fats help keep prostate cancer under control. It doesn't cure it though.