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Lloyd I. Sederer, MD

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Addiction: America's Most Neglected Disease

Posted: 06/26/2012 1:09 pm

The National Center on Addiction and Substance Abuse at Columbia University (CASA Columbia) released a report on addictions today that is remarkably comprehensive and even more remarkably honest in portraying the virtually utter failure to identify and effectively treat addiction in the U.S.

The report, titled "Addiction Medicine: Closing the Gap Between Science and Practice," starts with the premise that addiction is a disease. Addiction is not recreational drug use or risky behaviors (like adolescent binge drinking or buying drugs on the street). They focus on abuse and dependence on alcohol, legal and illicit drugs, and tobacco. While the authors recognize a group of addictive/compulsive behaviors, they are not covered in this report.

CASA Columbia is a renowned research center on addiction. For the past five years it brought together a team of addiction, public health and judicial experts, universities, medical centers, and other mainstream officials under the direction of Drew E. Altman, Ph.D., president and chief executive officer of the Kaiser Family Foundation, to study and survey the field of addiction in order to give us a landscape report of such precision and breadth. Scientific literature was reviewed, extensive surveys were conducted (throughout the U.S. and an in-depth survey in New York State), leading researchers and experts were interviewed, focus groups were held, and state and federal licensing, certification and accreditation rules and regulations were examined. Care was taken to hold to high standards of analysis and evidence. In short, this is one tome we ignore at our own peril.

Their definition of addiction is alcohol and drug (including tobacco) abuse (compulsive use despite clear harm to relationships, work and physical health) and dependence (where the body experiences withdrawal when blood levels of a substance drop).

Their definition of treatment is that of psychological and social therapies (like motivational interviewing/motivational enhancement therapy, cognitive behavioral therapy -- CBT -- provided individually and in groups, the often highly-effective but controversial contingency management approaches that reward abstinence, and family therapies) and medications used to treat additions (like naltrexone, nicotine replacement and buprenorphine -- see here and here). They do not include detoxification (typically repetitive, expensive, and often medically-unnecessary interventions that are generally ineffective in promoting recovery), peer- and religious-based counseling, emergency room and prison/jail services. Don't bother to pick up this 573-page report (more than half of which is appendices and references) if you believe addiction is a failure of will, a form of moral turpitude, or habits where people should "just get over it" (though some future campaign should try to change your mind).

The consequences of untreated addiction, and its predecessor risky alcohol and drug use, are chilling. The report concludes that:

"Risky substance use and addiction constitute the largest preventable public health problems and the leading causes of preventable death (emphasis mine) in the U.S. Of the nearly 2.5 million deaths in 2009, an estimated minimum of 578,819 were attributable to tobacco, alcohol or other drugs."


The report also estimates the costs of addiction and risky substance use behaviors to government coffers alone to exceed $468 billion annually. Yet, and here is the most important finding of all, only one in 10 people with addiction to alcohol and/or drugs report receiving any treatment -- at all. Can you imagine that measure of neglect were the conditions heart or lung disease, cancer(s), asthma, diabetes, tuberculosis, or stroke and other diseases of the brain?

Tobacco use is the leading preventable cause of death and disability in this country. But the catastrophic effects of addiction do not stop there: The report considers car crashes, where 40 percent of fatalities involve someone under the influence; the five-fold increase in prescription drug overdose deaths since 1990, where OD fatalities exceed traffic accidents; increased risk of heart and lung diseases, cancer and sexually-transmitted diseases; and parental substance abuse, which increases the risk of their children performing poorly in school and developing conduct and trauma disorders, asthma, ADHD, depression and, of course, addiction itself. Family dysfunction warrants particular notation, since addiction produces financial and legal problems (property and violent crimes) and increases domestic violence, child abuse, unplanned pregnancies, and motor vehicle accidents.

The report is exhaustive in the ways it considers legal and illicit drugs, alcohol, and tobacco. Each section is clear, compelling and exceptionally well-supported with tables and references. A thorough analysis of why we are at this deeply troubling state of neglect examines how addiction has been systematically omitted from medical care, how treatment providers are terribly undertrained to deliver a range of proven treatments, how treatment programs are not sufficiently held accountable for delivering evidence-based practices, and how private insurance payers have eluded the provision of adequate benefits and defaulted payment to the public sector. But what we need to know far beyond the inescapable evidence of how big and bad the problems are is what can be done?

The opening recommendation is a page out of every good textbook of public health. Start by detecting a problem that is -- by inattention or aversion -- kept out of sight. We do not deal with what we do not confront. More than 80 million people (!) in this country ages 12 and older abusively engage in substance use without meeting criteria for addiction (defined above) and represent an exceptional opportunity to intervene early and effectively, yet this is not happening. Simple screening tests for alcohol, drugs and tobacco exist and can be made standard practice throughout medical care (and in educational and counseling settings). SBIRT -- Screening, Brief Intervention and Referral for Treatment -- is a recognized, proven and even reimbursed medical procedure that awaits general use despite the consequences of not using it.

The report offers a set of treatment recommendations and asserts importantly that comprehensive treatment (combining psychosocial and pharmacological interventions) is generally better than reliance on one approach alone. There is an abundance of information on treatment, beginning with stabilization of the disease and continuing on to acute care with therapy and medications. The authors provide critically-important and urgently-needed information about how chronic disease management techniques extant throughout medicine today need to be applied to addiction. Nutrition and exercise are woven into the treatment approaches. AA, NA, SMART and other longstanding and effective recovery programs find their way into the report as "support services," revealing its particularly medical and judicial framework.

One finding that may pertain to readers of this post, or people they know, is that public attitudes about the causes of addiction "... are out of sync with the science." Their survey work reveals that one-third of Americans still regard addiction as a "... lack of willpower or self-control." We can be our own worst enemy, and local and national efforts to change minds and hearts are needed.

Further recommendations are framed as major sections on how to close the science-to-practice gap (to make happen in everyday practice what we know from science that works): commencing a national public education campaign, mandating program adherence to proven practices, establishing quality improvement tools and procedures to steadily and progressively improve program performance, insurance reform, and organizing federal oversight into one agency on addiction.

There is so much more in the report that this summary cannot cover. Among the findings readers may also want to take guidance from are on special populations (from youth to the elderly, and including veterans, pregnant women and those with co-occurring medical and mental health disorders), on parity legislation and the do-or-die role of funding prevention and services, and on education and practice standards. The report serves both as a call to action and an encyclopedic warehouse of information.

The CASA Columbia report's strengths are its veracity, clarity and credibility, the last based on the excellent science they summarize and the caliber of the report's authors. A shortcoming is that it was developed by experts in medicine, addictions, public health and jurisprudence; as a result, it does not report on the emerging and abundantly-used field of complementary and alternative approaches to addiction "treatment" (such as yoga and acupuncture) nor dedicate much report real estate to 12-step and related recovery models. Nor does the report consider how making legal substances more expensive and more difficult to get could be used as means of controlling youth drinking and other compulsive habits, though CASA Columbia did consider these interventions last year in a report on adolescent substance abuse (see here and here).

Practitioners, policy makers, educators and responsible citizens should more than consider "Addiction Medicine: Closing the Gap Between Science and Practice." It needs to become an agenda for action. Not doing so will mean that this country would have decided to continue to neglect its most prevalent, destructive and costly of diseases.

---

The Huffington Post soon will be publishing a series on alternatives to 12-step and medication-assisted recovery. Readers will have an opportunity to comment and debate on the topics covered.

Lloyd I. Sederer, MD

www.askdrlloyd.com

The opinions expressed here are solely mine as a psychiatrist and public health advocate. I receive no support from any pharmaceutical or device company.

Visit Dr. Sederer's website (www.askdrlloyd.com) for questions you want answered, reviews, commentary and stories.

For more by Lloyd I. Sederer, M.D., click here.

For more on addiction and recovery, click here.

 
 
 
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10:41 PM on 06/30/2012
Yeah? Therapists? They don't seem to know what they are talking about when it comes to Substance Abuse. I finally found a good therapist, but it took a long time. I've taken a graduate level in substance abuse counseling, and the students could have learned more by going to AA or NA every night for a month than from what was taught in that class. AA and NA is the only treatment most people get, and this report doesn't include that?

Now, don't get me wrong, I wouldn't be sober without a good therapist who knew how to treat concurrent PTSD and substance abuse.
04:45 AM on 06/29/2012
Maybe tobacco is bad, but it's our choice. Bob Dole says he doesn't believe they are addictive.
StevenRussell1
Christian Pilot
04:34 AM on 06/28/2012
"America's most neglected disease" - Sin.
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Ronald Zelman
Independent But Not Alone!
02:14 AM on 06/28/2012
Americas most neglected disease is ignorance.
12:35 AM on 06/28/2012
Why was I able to guess that The Huffington Post would run a series of articles on alternative approaches to Alcoholics Anonymous -- the best program for the most number of people ever devised. What's the point? Just teach people how to use AA effectively and dispense with the controlled drinkng and anti-AA nonsense.
01:15 AM on 06/28/2012
"the best program for the most number of people ever devised"

http://www.ncbi.nlm.nih.gov/pubmed/19340677/

If this is the best ever devised, it's time to look for better.
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GOODDOC1
"civil war" is an oxymoron
02:49 AM on 06/28/2012
AA works GREAT for most people. But there are just some people who can't seem to get a handle on it. I'm glad there are possibilities for them as well.
11:45 PM on 06/27/2012
Ah here we go, the rehab industry trying to drum up more paranoia to support their steady influx of new "customers". Addiction might be one of the trendiest "diseases" now but its definitely not the most neglected. Better cut the costs of our futile "War on drugs" out of what it costs us, and factor in what they make through the whole dwi/drug bust mandatory rehab and fines extortion racket and im sure itll balance out. plus what the pharmaceutical companies make producing way more pills than necessary knowing theyre going to wind up being sold on the street. For the record, actual addiction, as in living on the streets and not thinking about anything but getting enough change for the next bottle of whatevers cheapest at the liquor store definitely IS a real sickness that takes help to overcome, but our war on drugs is more interested in people caught with a bag of weed on a friday night than actual sick people.
11:08 PM on 06/27/2012
Any ex-smokers up in here with advice on quitting smoking? I'd appreciate it.
11:30 PM on 06/27/2012
I tried everything. The patch, doctors pills, cold turkey, hypnosis (lasted 9 months until stressful episode). Its so hard. But when you get to the point where your 40, your blood pressure is stage 2 hypertension and you dont have insurance to get blood pressure pills. Well, for me my head started to hurt. Real bad headaches everyday. Because I smoke I dont feel like eating right or excersizing so I gain weight. It all becomes to much, almost to the point where you absolutley hate smoking and have to stop and lose wieght and focus on health. For me it is either quit or die. When its time its just time and the part of your brain that has been sabotaging you for so long can be crushed by the other have that is saying hey wait, you are causing pain and death.
08:53 AM on 06/30/2012
I smoked for 34 years, and up to 1 1/2 packs to 2 packs a day. I quit in February of 2007. The doctor said I had the lungs of a 90 year old, and the beginnings of emphysema, and as a singer, couldn't sustain notes anymore ... I couldn't sing!
I used the patch in conjunction with chantix, under doctor supervision. I was the hardest thing I ever had to do, but I got it done! Can't stand the smell of cigarette smoke now. Good luck ... you can do it!
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HUFFPOST SUPER USER
deputy85
Rightwing,retired n doing great
10:17 PM on 06/27/2012
Addiction is new age speak for weakness, no one made you in fact many told you dont,, you choose to start the habbit whatever it is, now you cry because you have a diease? i dont buy it never have ,it's a choosen problem, a diease is not of one's choosing ,
10:37 PM on 06/27/2012
Did you even read the story? Your just going to ignore all the research? You probably believe we lived with dinosaurs 4000 years ago too right?
10:45 PM on 06/27/2012
"i dont buy it never have ,it's a choosen problem, a diease is not of one's choosing ,"

How's your salt intake?
12:41 AM on 06/28/2012
I didnt choose addiction
11:17 AM on 07/08/2012
I lost a teenager to a drug overdose. He had been in & out of rehab & had been clean 7 months when he died. I sat with this kid many times as he cried, "Mom, I screwed up. I just want to be a regular kid again." An immature choice by a kid trying to fit in flipped the addiction switch on. NO ON WAKES UP ONE MORNING THINKING THEY WANT TO BECOME AN ADDICT! Addiction often happens when a patient is prescribed pain medicine for true pain. It is often the result of a mental problem after a person is self -medicating for a coexisting disorder. My teenage son did not choose addiction anymore than one chooses diabetes or heart disease. There but for the Grace if God go I (and you).
09:10 PM on 06/27/2012
I've been trying to quit smoking since I started 25 years ago. Today I bought a pack, smoked 3 felt horrible and threw the rest away. Before today I had gone about a week without smoking. It has been my pattern now for months. I think I am getting to a one week flare-up and am unable to convince myself not to smoke. I know if I survive it the one month flare-up will do me in for sure. Addiction really sucks. I hate it. I feel like my brain has 2 parts, one is fighting for my life and health, the other is trying to destroy me for a few seconds of elevated blood pressure, increased heartbeat and whatever else stupid stuff comes with a puff.
10:12 PM on 06/27/2012
Tobacco is extremely hard to kick.
But unlike the contention in this article, it doesn't have the severity of ill health effects that alcohol and prescription drugs have. So you are way better off than people addicted to those at least.
Unfortunately kicking any of these drugs is a very slippery path and solutions vary widely from individual to individual.
It has nothing to do with will power.
10:33 PM on 06/27/2012
Whats weird is my parents both were born and raised in Europe. So they raised me the same way they were raised and that is by drinking wine at certain dinners even from a very young age. Yet now I rarely drink. Neither of them have ever smoked yet now I do.
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sylvia arotin
NJ
09:10 PM on 06/27/2012
Addiction is NOT a disease, it is a CHOICE!! You know before you stick that needle in your arm it is addictive and yet you CHOOSE TO DO IT.
09:27 PM on 06/27/2012
Most people don't start with a needle. Oh, and... your attitude contributes nothing useful at all.
10:13 PM on 06/27/2012
I agree with you. This kind of lack of empathy and ignorance is typical of some however.
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GOODDOC1
"civil war" is an oxymoron
02:57 AM on 06/28/2012
Sorry, but the entire medical establishment disagrees with you. And few, if any, start out with a needle. Why don't you borrow a magnifying glass and look for your heart. It's probably too late for you to find your brain, if you ever had one.
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HUFFPOST SUPER USER
pslcitizen
I intend to live forever. So far, so good.
08:36 PM on 06/27/2012
It sure is. Enough money to get your next fix but not enough to get fixed. I hope someone is getting clean today & also hope that someone stays clean today.
07:49 PM on 06/27/2012
One problem is that many doctors are simply just not educated on the subject of addiction. I know that it is not something that is covered very extensively in med school, and until recently, many family doctors had not experienced a high number of people faking medical conditions just to obtain pain meds. I went through a very nasty experience with vicodin and tramadol. I was prescribed vicodin for a shoulder reconstruction. When I told my doctor I was concerned about becoming addicted (I was in a difficult divorce at the time), he put me on tramadol and told me it was not addictive. He could not have been more wrong. It is a synthetic form of morphine and still to this day, is not a controlled substance. I went cold turkey and went through a hell that I would not wish upon anyone. When I told my doctor, he insisted I was making it up, because tramadol could not be addictive. Now, it's a huge problem for many people and many are trying to get it categorized as a controlled substance. I urge anyone who needs painkillers to do their homework. You can't always trust your doctor. Many get kickbacks from pharmaceutical companies to push their drugs. As a result, many suffer. In 2011, NHL enforcer Derek Boogaard of the N.Y. Rangers and still fan favorite here in Minnesota, died as a result of pain killer overdose. This is a serious issue that needs to be addressed now!!!
09:18 PM on 06/27/2012
"He could not have been more wrong. It is a synthetic form of morphine and still to this day, is not a controlled substance."

To the extent tramadol exhibits a withdrawal syndrome, the psychopharmacology is more complicated than opiate addiction, as it doesn't produce cross-tolerance with the actual opiods. And who gave you the bright idea to suddenly discontinue it? It takes long-term use for any dependence to develop (e.g., PMID 20589494 and references therein).
12:13 AM on 06/28/2012
What constitutes "long term use??" Wouldn't that differ with each individual? I quit on my own, after being told time and time again it wasn't addictive, therefore I would not experience any withdrawal symptoms. What a crock of crap.  I was on tramadol for approximately 1 1/2 to 2 months. Whether or not that is long term use, I do not know. But it was enough to cause me to go through withdrawal that I had never before, or since, have experienced. I have never taken street drugs, nor do I drink. Obviously I'm not a pharmacist, chemist, or any kind of medical professional. I played semi-pro hockey at the time and am currently an options trader. I am aware of others who have used tramadol. Most have had no trouble. Some have had terrible trouble and have gone to treatment. One individual I know is on a suboxone program after having severe cravings for tramadol after he discontinued it's use.
10:16 PM on 06/27/2012
It is not a matter of education in medical school because the medical profession has no answer for addiction.
Cold turkey withdrawal from many of these highly addictive pills doctors hand out like candy is absolute hell few can understand unless they go through it themselves. Least of all doctors.
10:40 PM on 06/27/2012
However, tramadol is not "highly addictive." Nor is it "handed out like candy"; it's a pretty good test of suspected drug-seekers if they refuse it or suddenly are "allergic." I've been prescribed tramadol twice--once after arthroscopic knee surgery and once after cracking a couple of ribs (the latter was worse). Both were #30, 50 mg, no refills. Demonization of appropriate pain management (and I'm not talking about pill mills off the interstate) is a problem in and of itself.
12:23 AM on 06/28/2012
The doctor I have now is more experienced with addiction. I told him what I went through. He is a strict believer that tramadol should be considered a controlled substance given it's high abuse potential. I'm sure, however, I would get a slew of different opinions from different doctors. I played hockey through college and into the semi-pro's. I found out real fast that doctors give these things out (painkillers) like it's nothing. I'm lucky I didn't get caught up in it at that time, but I do know others who ended up in treatment. A few had their lives completely turned upside down, losing their wives, homes and jobs. I got a taste of it. It's hell.
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Lisa Frederiksen
Author, Speaker, Consultant-BreakingTheCycles.com
07:22 PM on 06/27/2012
Thank you Dr. Sederer for this article. I have been researching, writing and speaking about the relatively new brain and addiction-related research since 2003. This research has only been possible in the past 10-15 years, thanks to advances in imaging technologies, such as fMRI and SPECT, that allow neuroscientists and medical professionals to study the live brain in action, over time and under the influence. It's fascinating to learn that addiction is a brain disease - how it happens and therefore how it can successfully be treated when it is treated for what it is - a brain disease. For readers wanting to understand this concept further, check out The Addiction Project, a collaboration of The National Institute on Alcohol Abuse (NIAAA), National Institute on Drug Abuse (NIDA), Robert Wood Johnson Foundation and HBO, http://tiny.cc/xe4kgw . It's excellent!
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HUFFPOST SUPER USER
jumpinjohn011
06:58 PM on 06/27/2012
The only way to arrest addiction (you are never cured) is admitting powerelessness over your addiction on a daily basis one day at a time!
10:56 PM on 06/27/2012
I'm afraid that 12-step programs really have very little in the way of evidence for efficacy. "Only way" is vastly overblown. Some they help, some they don't, some they worsen, and some they facilitate victimization of.
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jumpinjohn011
12:00 AM on 06/28/2012
Did I mention 12 steps?
HUFFPOST SUPER USER
jgamble28
ya never know.
06:39 PM on 06/27/2012
I think people know if their addicted or not but they don't want to get better. You can't make someone take the help if they are not ready.