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Clinical Trials

Cognitive Computing: Revolution's in the Air

Lynn Vos | Posted 06.18.2015 | Technology
Lynn Vos

The first intelligible words spoken over the telephone in March 1876 are reported to be, "Mr. Watson, come here. I want to see you." So perhaps it's only fitting new technology that may be as revolutionary for global healthcare shares that surname.

This Father's Day, Give 1 for Dad

D. Brad Wright | Posted 06.17.2015 | Parents
D. Brad Wright

This year, there will be no necktie, no book, no gift card to Amazon. Instead, I'm giving a donation to an important charity in honor of my Dad.

'Putting Your Bottom at the Top of Your List' -- The Pap Smear That's Not Just for Women

Erin N. Marcus, M.D. | Posted 06.27.2015 | Healthy Living
Erin N. Marcus, M.D.

Depending on the study's results, it's possible that anal health will become a routine conversation topic between doctors and patients -- and labs won't think twice when they receive a pap smear specimen from a man.

Children's Cancer Therapy Development Institute: A New Attempt at Bridge-Building for Childhood Cancer Research

Jonathan Agin | Posted 04.04.2015 | Impact
Jonathan Agin

We live in an era of immense hope for the future of cancer research and the quest for new and promising treatments. The identification of new genetic mutations as viable markers for therapeutic development is driving researchers and clinicians to focus on specific pathways for targeted therapies.

The Crisis of Confidence in Medical Research

Allen Frances | Posted 03.14.2015 | Science
Allen Frances

It's been many years since I have trusted anything I read in a medical or psychiatric journal. There is an enterprise wide positive bias; findings never seem to replicate; benefits are hyped; harms are hidden.

Informed Consent in Comparative Effectiveness Research

Ruth Macklin | Posted 02.27.2015 | Healthy Living
Ruth Macklin

"Standard of care" research (also known as "comparative effectiveness" research) is a design that compares two therapies in routine use to determine w...

Research Ethics and Ebola

Ruth Macklin | Posted 12.23.2014 | Science
Ruth Macklin

A letter published online in the Lancet on Oct. 10, by a distinguished group of scientists, ethicists and physicians from all over the world, makes an urgent plea for embarking on research for experimental Ebola treatments that would not randomize patients to a control arm that provides only conventional care or conventional care along with a placebo.

Pregnant Women Must Be Studied Too

Society for Women's Health Research | Posted 12.21.2014 | Healthy Living
Society for Women's Health Research

Imagine being pregnant while having a chronic health condition such as diabetes, hypertension, depression or asthma, or being diagnosed with an illness while pregnant. Amazingly, your doctor may not know exactly what treatments or drugs, or what dose, will work best for you. This is a reality faced by American women every day.

Homoground Is Throwing the First Queer CMJ Showcase Ever

Brett Gleason | Posted 12.20.2014 | Gay Voices
Brett Gleason

I approached Homoground founder Lynn Casper over the summer to help fill the gap in what I saw was a lack of LGBTQ representation in what's always been such a great week to check out new artists.

Jane Seymour: A Daughter's Dilemma and Her Compassionate Solution

Cary A. Presant, M.D. | Posted 12.08.2014 | Healthy Living
Cary A. Presant, M.D.

In June 2014, I had the joy of filming a cancer segment with Jane Seymour for her series "Feel Grand" supported by Grandparents.com for Detroit Public...

Ebola and Life-Threatening Diseases: Should You Take Untested Medicines?

Cary A. Presant, M.D. | Posted 11.29.2014 | Healthy Living
Cary A. Presant, M.D.

If a condition, even Ebola, threatens your life, be courageous, be informed, and be prepared to make a decision that could help you survive.

Part II: When Mad Men Met a Sedative -- False Hype, Fake Numbers and Untold Birth Defects

Eileen Cronin | Posted 11.26.2014 | Healthy Living
Eileen Cronin

While this chapter of FDA history is behind us, the damages of thalidomide's "clinical trials" continue to reveal themselves more than 50 years later.

Make No Small Plans

Bret Hoekema | Posted 11.22.2014 | Healthy Living
Bret Hoekema

The day I received the results of my first PET scan still haunts me. I've felt so foolish for feeling so confident.

Gender-Based Medicine: The Path to Better Health for Women

Luise Meyer | Posted 11.08.2014 | Science
Luise Meyer

Gender-based medicine is a budding 21st-century concept. New and fascinating findings are frequent in this field of study. However, the full extent of gender differences in medicine is still to be seen, and for that we rely entirely on research in gender biology and the forward push to ensure proper gender representation in clinical trials.

Part I: When Mad Men Met a Sedative -- How U.S. Doctors Were Duped Into Doling Out a Toxic Drug

Eileen Cronin | Posted 11.06.2014 | Healthy Living
Eileen Cronin

In part one of our follow-up series on thalidomide, we focus on the pseudo "clinical trials" and gross negligence of Richardson-Merrell, which distributed thalidomide to 1,267 U.S. physicians.

Why Women Need Equal Treatment In Medical Research

Phyllis Greenberger | Posted 10.24.2014 | Healthy Living
Phyllis Greenberger

Who would have thought that in 2014 we would be fighting to ensure that women are included in research on diseases and medical drugs and devices? If you find it outrageous, you are not alone.

The Ethics Of The Ebola Outbreak: Who Should Receive Experimental Treatment?

Ruth Macklin | Posted 10.21.2014 | Healthy Living
Ruth Macklin

The need for these drugs is greatest in the countries where the epidemic is raging. Their residents come first. Because clinical trials for safety and efficacy can be carried out only in such countries, even the "compassionate use" of an unproven drug in severely limited supply should be granted first to inhabitants of the nations that have been most severely affected.

The West Africa Ebola Epidemic Arouses Global Response But Caution Needs an Ally and a Local Interpreter

Sharon Hrynkow PhD | Posted 10.15.2014 | Healthy Living
Sharon Hrynkow PhD

When Ebola drugs and vaccines become available, trust -- engendered best by knowledgeable local leaders - may be the vital ingredient in ensuring that drugs are distributed most quickly to those in need.

6 Tips About Breakthrough Drugs: For Example, Should Breast Cancer Patients Try to Get Palbociclib?

Cary A. Presant, M.D. | Posted 10.12.2014 | Healthy Living
Cary A. Presant, M.D.

Breakthrough drugs are widely covered in the media. After hearing about these new drugs, patients and their families are always asking me how they can get access to the new medicine or participate in a clinical trial of the new drug. Let's look at a current example.

Adding Meaning to a Life Taken Too Soon: Ten Years Later

Jay Scott | Posted 09.30.2014 | Impact
Jay Scott

This Friday, August 1, 2014 will mark 10 years since my daughter Alex lost her life to neuroblastoma, a form of childhood cancer, at just 8 years of age.

American Innovation for NCDs

Michael Hodin | Posted 09.28.2014 | Fifty
Michael Hodin

Twenty first century health challenges - exacerbated by age-related NCDs - require 21st century solutions.

A Message to Girls and Graduates Interested in STEM: Don't Give Up!

Kimberly Kiel | Posted 08.12.2014 | Science
Kimberly Kiel

Have you ever glanced at a photograph from years before and had a rush of emotion and memories come flooding into your remembrance? This happened to me when I saw my college graduation photos a few weeks ago.

The Problem of Health Inequity Unites Us All

Laurie Fenton Ambrose | Posted 07.17.2014 | Impact
Laurie Fenton Ambrose

When studies take place, researchers often fail to analyze data by sex or include sex-specific factors, making it difficult to uncover differences in incidence, prevalence and survivability between men and women.

Got Advanced Cancer? Consider Clinical Trials

Deborah J. Cornwall | Posted 07.07.2014 | Healthy Living
Deborah J. Cornwall

Increased volunteer participation in trials offers patients access to cutting-edge treatments and contributes to the development of better treatments to prolong life and eventually drive those cancers into remission.

The Compassionate Use Conundrum

Jonathan Agin | Posted 06.23.2014 | Impact
Jonathan Agin

The bad news is that in many instances, the drugs that show promise for these newly found targets are not available for that form of cancer treatment. And that brings us full circle.