In 2000, Douglas Hanahan and Robert A. Weinberg articulated the concept of cancer hallmarks as a foundation for understanding cancer's biology across traditional cancer types. Three initiatives built on that foundation now promise to accelerate development of more powerful life-saving therapies.
The show had one purpose and that was to raise money and not to address other issues in the cancer continuum. The questions raised in my mind while watching the show were just from me reading between the lines.
Six years after the launch of SU2C, there a strong feeling that we are on the verge of significant breakthroughs made possible by our much better understanding of the molecular mechanisms giving rise to cancer.
From The Today Show, to the Apollo Theatre, telethons and fundraisers -- Avalanna never found a microphone she did not fall in love with. One of her greatest adventures was meeting Justin Bieber. In typical Avalanna fashion, she was completely unfazed by Justin's fame.
The courage and immediacy that Laura infused into everything she did continues to live on in all of us at Stand Up to Cancer. Because Laura Ziskin asked the question "why?" and acted on it, cancer research today is being done differently, all for the benefit of patients.
When I was 27 years old, four words changed my life: "Positive for a deleterious mutation." Translated into English, that meant I was carrying the mutated gene that triggered the breast and ovarian cancer suffered by my mother, grandmother and great aunts.