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Sam Harris

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Drugs and the Meaning of Life

Posted: 07/06/2011 9:43 am

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(Photo by JB Banks)

Everything we do is for the purpose of altering consciousness. We form friendships so that we can feel certain emotions, like love, and avoid others, like loneliness. We eat specific foods to enjoy their fleeting presence on our tongues. We read for the pleasure of thinking another person's thoughts. Every waking moment--and even in our dreams--we struggle to direct the flow of sensation, emotion, and cognition toward states of consciousness that we value.

Drugs are another means toward this end. Some are illegal; some are stigmatized; some are dangerous--though, perversely, these sets only partially intersect. There are drugs of extraordinary power and utility, like psilocybin (the active compound in "magic mushrooms") and lysergic acid diethylamide (LSD), which pose no apparent risk of addiction and are physically well-tolerated, and yet one can still be sent to prison for their use--while drugs like tobacco and alcohol, which have ruined countless lives, are enjoyed ad libitum in almost every society on earth. There are other points on this continuum--3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy") has remarkable therapeutic potential, but it is also susceptible to abuse, and it appears to be neurotoxic.[1]

One of the great responsibilities we have as a society is to educate ourselves, along with the next generation, about which substances are worth ingesting, and for what purpose, and which are not. The problem, however, is that we refer to all biologically active compounds by a single term--"drugs"--and this makes it nearly impossible to have an intelligent discussion about the psychological, medical, ethical, and legal issues surrounding their use. The poverty of our language has been only slightly eased by the introduction of terms like "psychedelics" to differentiate certain visionary compounds, which can produce extraordinary states of ecstasy and insight, from "narcotics" and other classic agents of stupefaction and abuse.

Drug abuse and addiction are real problems, of course--the remedy for which is education and medical treatment, not incarceration. In fact, the worst drugs of abuse in the United States now appear to be prescription painkillers, like oxycodone. Should these medicines be made illegal? Of course not. People need to be informed about them, and addicts need treatment. And all drugs--including alcohol, cigarettes, and aspirin--must be kept out of the hands of children.

I discuss issues of drug policy in some detail in my first book, The End of Faith (pp. 158-164), and my thinking on the subject has not changed. The "war on drugs" has been well lost, and should never have been waged. While it isn't explicitly protected by the U.S. Constitution, I can think of no political right more fundamental than the right to peacefully steward the contents of one's own consciousness. The fact that we pointlessly ruin the lives of nonviolent drug users by incarcerating them, at enormous expense, constitutes one of the great moral failures of our time. (And the fact that we make room for them in our prisons by paroling murderers and rapists makes one wonder whether civilization isn't simply doomed.)

I have a daughter who will one day take drugs. Of course, I will do everything in my power to see that she chooses her drugs wisely, but a life without drugs is neither foreseeable, nor, I think, desirable. Someday, I hope she enjoys a morning cup of tea or coffee as much as I do. If my daughter drinks alcohol as an adult, as she probably will, I will encourage her to do it safely. If she chooses to smoke marijuana, I will urge moderation.[2] Tobacco should be shunned, of course, and I will do everything within the bounds of decent parenting to steer her away from it. Needless to say, if I knew my daughter would eventually develop a fondness for methamphetamine or crack cocaine, I might never sleep again. But if she does not try a psychedelic like psilocybin or LSD at least once in her adult life, I will worry that she may have missed one of the most important rites of passage a human being can experience.

This is not to say that everyone should take psychedelics. As I will make clear below, these drugs pose certain dangers. Undoubtedly, there are people who cannot afford to give the anchor of sanity even the slightest tug. It has been many years since I have taken psychedelics, in fact, and my abstinence is borne of a healthy respect for the risks involved. However, there was a period in my early 20's when I found drugs like psilocybin and LSD to be indispensable tools of insight, and some of the most important hours of my life were spent under their influence. I think it quite possible that I might never have discovered that there was an inner landscape of mind worth exploring without having first pressed this pharmacological advantage.

While human beings have ingested plant-based psychedelics for millennia, scientific research on these compounds did not begin until the 1950's. By 1965, a thousand studies had been published, primarily on psilocybin and LSD, many of which attested to the usefulness of psychedelics in the treatment of clinical depression, obsessive compulsive disorder (OCD), alcohol addiction, and the pain and anxiety associated with terminal cancer. Within a few years, however, this entire field of research was abolished in an effort to stem the spread of these drugs among the general public. After a hiatus that lasted an entire generation, scientific research on the pharmacology and therapeutic value of psychedelics has quietly resumed.

The psychedelics include chemicals like psilocybin, LSD, DMT, and mescaline--all of which powerfully alter cognition, perception, and mood. Most seem to exert their influence through the serotonin system in the brain, primarily by binding to 5-HT2A receptors (though several have affinity for other receptors as well), leading to increased neuronal activity in prefrontal cortex (PFC). While the PFC in turn modulates subcortical dopamine production, the effect of psychedelics appears to take place largely outside dopamine pathways (which might explain why these drugs are not habit forming).

The mere existence of psychedelics would seem to establish the material basis of mental and spiritual life beyond any doubt--for the introduction of these substances into the brain is the obvious cause of any numinous apocalypse that follows. It is possible, however, if not actually plausible, to seize this datum from the other end and argue, and Aldous Huxley did in his classic essay, The Doors of Perception, that the primary function of the brain could be eliminative: its purpose could be to prevent some vast, transpersonal dimension of mind from flooding consciousness, thereby allowing apes like ourselves to make their way in the world without being dazzled at every step by visionary phenomena irrelevant to their survival. Huxley thought that if the brain were a kind of "reducing valve" for "Mind at Large," this would explain the efficacy of psychedelics: They could simply be a material means of opening the tap.

Unfortunately, Huxley was operating under the erroneous assumption that psychedelics decrease brain activity. However, modern techniques of neuroimaging have shown that these drugs tend to increase activity in many regions of the cortex (and in subcortical structures as well). Still, the action of these drugs does not rule out dualism, or the existence of realms of mind beyond the brain--but then nothing does. This is one of the problems with views of this kind: They appear to be unfalsifiable.[3]

Of course, the brain does filter an extraordinary amount of information from consciousness. And, like many who have taken these drugs, I can attest that psychedelics certainly throw open the gates. Needless to say, positing the existence of a "Mind at Large" is more tempting in some states of consciousness than in others. And the question of which view of reality we should privilege is, at times, worth considering. But these drugs can also produce mental states that are best viewed in clinical terms as forms of psychosis. As a general matter, I believe we should be very slow to make conclusions about the nature of the cosmos based upon inner experience -- no matter how profound these experiences seem.

However, there is no question that the mind is vaster and more fluid than our ordinary, waking consciousness suggests. Consequently, it is impossible to communicate the profundity (or seeming profundity) of psychedelic states to those who have never had such experiences themselves. It is, in fact, difficult to remind oneself of the power of these states once they have passed.

Many people wonder about the difference between meditation (and other contemplative practices) and psychedelics. Are these drugs a form of cheating, or are they the one, indispensable vehicle for authentic awakening? They are neither. Many people don't realize that all psychoactive drugs modulate the existing neurochemistry of the brain--either by mimicking specific neurotransmitters or by causing the neurotransmitters themselves to be more active. There is nothing that one can experience on a drug that is not, at some level, an expression of the brain's potential. Hence, whatever one has experienced after ingesting a drug like LSD is likely to have been experienced, by someone, somewhere, without it.

However, it cannot be denied that psychedelics are a uniquely potent means of altering consciousness. If a person learns to meditate, pray, chant, do yoga, etc., there is no guarantee that anything will happen. Depending on his aptitude, interest, etc., boredom could be the only reward for his efforts. If, however, a person ingests 100 micrograms of LSD, what will happen next will depend on a variety of factors, but there is absolutely no question that something will happen. And boredom is simply not in the cards. Within the hour, the significance of his existence will bear down upon our hero like an avalanche. As Terence McKenna[4] never tired of pointing out, this guarantee of profound effect, for better or worse, is what separates psychedelics from every other method of spiritual inquiry. It is, however, a difference that brings with it certain liabilities.

Ingesting a powerful dose of a psychedelic drug is like strapping oneself to a rocket without a guidance system. One might wind up somewhere worth going--and, depending on the compound and one's "set and setting," certain trajectories are more likely than others. But however methodically one prepares for the voyage, one can still be hurled into states of mind so painful and confusing as to be indistinguishable from psychosis. Hence, the terms "psychotomimetic" and "psychotogenic" that are occasionally applied to these drugs.

I have visited both extremes on the psychedelic continuum. The positive experiences were more sublime than I could have ever imagined or than I can now faithfully recall. These chemicals disclose layers of beauty that art is powerless to capture and for which the beauty of Nature herself is a mere simulacrum. It is one thing to be awestruck by the sight of a giant redwood and to be amazed at the details of its history and underlying biology. It is quite another to spend an apparent eternity in egoless communion with it. Positive psychedelic experiences often reveal how wondrously at ease in the universe a human being can be--and for most of us, normal waking consciousness does not offer so much as a glimmer of these deeper possibilities.

People generally come away from such experiences with a sense that our conventional states of consciousness obscure and truncate insights and emotions that are sacred. If the patriarchs and matriarchs of the world's religions experienced such states of mind, many of their claims about the nature of reality can make subjective sense. The beautific vision does not tell you anything about the birth of the cosmos--but it does reveal how utterly transfigured a mind can be by a full collision with the present moment.

But as the peaks are high, the valleys are deep. My "bad trips" were, without question, the most harrowing hours I have ever suffered--and they make the notion of hell, as a metaphor if not a destination, seem perfectly apt. If nothing else, these excruciating experiences can become a source of compassion. I think it would be impossible to have any sense of what it is like to suffer from mental illness without having briefly touched its shores.

At both ends of the continuum time dilates in ways that cannot be described--apart from saying that these experiences can seem eternal. I have had sessions, both positive and negative, in which any knowledge that I had ingested a drug had been entirely extinguished, and all memories of my past along with it. Full immersion in the present moment, to this degree, is synonymous with the feeling that one has always been, and will always be, in precisely this condition. Depending on the character of one's experience at that point, notions of salvation and damnation do not seem hyperbolic. In my experience, Blake's line about beholding "eternity in an hour" neither promises, nor threatens, too much.

In the beginning, my experiences with psilocybin and LSD were so positive that I could not believe a bad trip was possible. Notions of "set and setting," admittedly vague, seemed sufficient to account for this. My mental set was exactly as it needed to be--I was a spiritually serious investigator of my own mind--and my setting was generally one of either natural beauty or secure solitude.

I cannot account for why my adventures with psychedelics were uniformly pleasant until they weren't--but when the doors to hell finally opened, they appear to have been left permanently ajar. Thereafter, whether or not a trip was good in the aggregate, it generally entailed some harrowing detour on the path to sublimity. Have you ever traveled, beyond all mere metaphors, to the Mountain of Shame and stayed for a thousand years? I do not recommend it.

2011-07-06-Pokhara.jpg

(Pokhara, Nepal)

On my first trip to Nepal, I took a rowboat out on Phewa Lake in Pokhara, which offers a stunning view of the Annapurna range. It was early morning, and I was alone. As the sun rose over the water, I ingested 400 micrograms of LSD. I was 20 years old and had taken the drug at least ten times previously. What could go wrong?

Everything, as it turns out. Well, not everything--I didn't drown. And I have a vague memory of drifting ashore and of being surrounded by a group of Nepali soldiers. After watching me for a while, as I ogled them over the gunwale like a lunatic, they seemed on the verge of deciding what to do with me. Some polite words of Esperanto, and a few, mad oar strokes, and I was off shore and into oblivion. So I suppose that could have ended differently.

But soon there was no lake or mountains or boat--and if I had fallen into the water I am pretty sure there would have been no one to swim. For the next several hours my mind became the perfect instrument of self-torture. All that remained was a continuous shattering and terror for which I have no words.

These encounters take something out of you. Even if drugs like LSD are biologically safe, the potential for extremely unpleasant and destabilizing experiences presents its own risks. I believe I was positively affected for weeks and months by my good trips, and negatively affected by the bad ones. Given these roulette-like odds, one can only recommend these experiences with caution.

While meditation can open the mind to a similar range of conscious states, they are reached far less haphazardly. If LSD is like being strapped to rocket, learning to meditate is like gently raising a sail. Yes, it is possible, even with guidance, to wind up someplace terrifying--and there are people who probably shouldn't spend long periods in intensive practice. But the general effect of meditation training is of settling ever more fully into one's own skin, and suffering less, rather than more there.

As I discussed in The End of Faith, I view most psychedelic experiences as potentially misleading. Psychedelics do not guarantee wisdom. They merely guarantee more content. And visionary experiences, considered in their totality, appear to me to be ethically neutral. Therefore, it seems that psychedelic ecstasy must be steered toward our personal and collective well-being by some other principle. As Daniel Pinchbeck pointed out in his highly entertaining book, Breaking Open the Head, the fact that both the Mayans and the Aztecs used psychedelics, while being enthusiastic practitioners of human sacrifice, makes any idealistic link between plant-based shamanism and an enlightened society seem terribly naive.

As I will discuss in future essays, the form of transcendence that appears to link directly to ethical behavior and human well-being is the transcendence of egoity in the midst of ordinary waking consciousness. It is by ceasing to cling to the contents of consciousness--to our thoughts, moods, desires, etc.--that we make progress. Such a project does not, in principle, require that we experience more contents.[5] The freedom from self that is both the goal and foundation of "spiritual" life is coincident with normal perception and cognition--though, admittedly, this can be difficult to realize.

The power of psychedelics, however, is that they often reveal, in the span of a few hours, depths of awe and understanding that can otherwise elude us for a lifetime. As is often the case, William James said it about as well as words permit[6] :

One conclusion was forced upon my mind at that time, and my impression of its truth has ever since remained unshaken. It is that our normal waking consciousness, rational consciousness as we call it, is but one special type of consciousness, whilst all about it, parted from it by the filmiest of screens, there lie potential forms of consciousness entirely different. We may go through life without suspecting their existence; but apply the requisite stimulus, and at a touch they are there in all their completeness, definite types of mentality which probably somewhere have their field of application and adaptation. No account of the universe in its totality can be final which leaves these other forms of consciousness quite disregarded. How to regard them is the question,--for they are so discontinuous with ordinary consciousness. Yet they may determine attitudes though they cannot furnish formulas, and open a region though they fail to give a map. At any rate, they forbid a premature closing of our accounts with reality.

(The Varieties of Religious Experience, p. 388)


NOTES:

  1. A wide literature now suggests that MDMA damages serotonin-producing neurons and decreases levels of serotonin in the brain. Here is the tip of the iceberg: 1, 2, 3, 4, 5, and 6.
  2. What is moderation? Let's just say that I've never met a person who smokes marijuana every day who I thought wouldn't benefit from smoking less (and I've never met someone who has never tried it who I thought wouldn't benefit from smoking more).
  3. Physicalism, by contrast, could be easily falsified. If science ever established the existence of ghosts, or reincarnation, or any other phenomenon which would place the human mind (in whole or in part) outside the brain, physicalism would be dead. The fact that dualists can never say what would count as evidence against their views makes this ancient philosophical position very difficult to distinguish from religious faith.
  4. Terence McKenna is one person I regret not getting to know. Unfortunately, he died from brain cancer in 2000, at the age of 53. His books are well worth reading, and I have recommended several below, but he was, above all, an amazing speaker. It is true that his eloquence often led him to adopt positions which can only be described (charitably) as "wacky," but the man was undeniably brilliant and always worth listening to.
  5. I should say, however, that there are psychedelic experiences that I have not had, which appear to deliver a different message. Rather than being states in which the boundaries of the self are dissolved, some people have experiences in which the self (in some form) appears to be transported elsewhere. This phenomenon is very common with the drug DMT, and it can lead its initiates to some very startling conclusions about the nature of reality. More than anyone else, Terence McKenna was influential in bringing the phenomenology of DMT into prominence.



    DMT is unique among psychedelics for a several reasons. Everyone who has tried it seems to agree that it is the most potent hallucinogen available (not in terms of the quantity needed for an effective dose, but in terms of its effects). It is also, paradoxically, the shortest acting. While the effects of LSD can last ten hours, the DMT trance dawns in less than a minute and subsides in ten. One reason for such steep pharmacokinetics seems to be that this compound already exists inside the human brain, and it is readily metabolized by monoaminoxidase. DMT is in the same chemical class as psilocybin and the neurotransmitter serotonin (but, in addition to having an affinity for 5-HT2A receptors, it has been shown to bind to the sigma-1 receptor and modulate Na+ channels). Its function in the human body remains mysterious. Among the many mysteries and insults presented by DMT, it offers a final mockery of our drug laws: Not only have we criminalized naturally occurring substances, like cannabis; we have criminalized one of our own neurotransmitters.



    Many users of DMT report being thrust under its influence into an adjacent reality where they are met by alien beings who appear intent upon sharing information and demonstrating the use of inscrutable technologies. The convergence of hundreds of such reports, many from first-time users of the drug who have not been told what to expect, is certainly interesting. It is also worth noting these accounts are almost entirely free of religious imagery. One appears far more likely to meet extraterrestrials or elves on DMT than traditional saints or angels. As I have not tried DMT, and have not had an experience of the sort that its users describe, I don't know what to make of any of this.
  6. Of course, James was reporting his experiences with nitrous oxide, which is an anesthetic. Other anesthetics, like ketamine hydrochloride and phencyclidine hydrochloride (PCP), have similar effects on mood and cognition at low doses. However, there are many differences between these drugs and classic psychedelics--one being that high doses of the latter do not lead to general anesthesia.

Recommended Reading:

Huxley, A. The Doors of Perception and Heaven and Hell.

McKenna, T. Food of the Gods: The Search for the Original Tree of Knowledge A Radical History of Plants, Drugs, and Human Evolution.

McKenna, T. The Archaic Revival: Speculations on Psychedelic Mushrooms, the Amazon, Virtual Reality, UFOs, Evolution, Shamanism, the Rebirth of the Goddess, and the End of History.

McKenna, T. True Hallucinations: Being an Account of the Author's Extraordinary Adventures in the Devil's Paradise.

Pinchbeck, D. Breaking Open the Head: A Psychedelic Journey into the Heart of Contemporary Shamanism.

Stevens, J. Storming Heaven: LSD and the American Dream.

Ratsch, C. The Encyclopedia of Psychoactive Plants: Ethnopharmacology and Its Applications.

Ott, J. Pharmacotheon: Entheogenic Drugs, Their Plant Sources and History.

Strassman, R. DMT: The Spirit Molecule: A Doctor's Revolutionary Research into the Biology of Near-Death and Mystical Experiences.

 
 
 

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12:56 PM on 07/20/2011
That was a very sane article.
11:26 AM on 07/19/2011
> Still, the action of these drugs does not rule out dualism, or the existence of realms of mind beyond the brain--but then nothing does. This is one of the problems with views of this kind: They appear to be unfalsifiable ..

You lost me there Dude ... I guess you never came back from your trip ..
05:00 PM on 07/25/2011
Or that you should learn how to use a dictionary? I found the article to be intelligent and thoughtful.
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electrosef
Blue-green-purple Reality exposure
09:12 PM on 07/11/2011
A great, and IMO, a courageous article Dr. Sam. Kudos.
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S Andersen
Human flourishing is the first priority
01:20 AM on 07/11/2011
As always, Sam Harris provides clarity of thought and depth of analysis with erudition.

End the War on Drugs Now!
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Rubyfoo
09:55 PM on 07/10/2011
IMHO there's no one size fits all recommendation. Good for some, bad for others. Hard to know ahead of time.
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Alex0393
Are you people for real?
03:28 PM on 07/10/2011
I love drugs. In fact I loved them so much they destroyed my life and helped me to lose everything I have including my family. The only semi rational thing he says here is that nonviolent drug users shouldn't be jailed with violent ones. But, as things stand they are and it's a horrible place to be, trust me on this one. This is the most irresponsible writing I have ever read. When he said he hoped his daughter gave lsd a shot or whatever the sentence was, I had to go back and reread it to make sure there wasn't a typo. I don't want to ride in a car with anyone tripping on anything and doubt seriously any of you do either. It's a fine world we live in where this article is applauded but write one about the positive changes becoming a Christian can do and you will be assasinated verbally as I will be. You people are insane
Genders
Love, Tolerance, Enlightenment
08:16 PM on 07/10/2011
Sure that's actually you. sorry, but it sounds so much like Reefer madness. What drugs did you take, under what condition, in what quantifies?
Genders
Love, Tolerance, Enlightenment
08:16 PM on 07/10/2011
BTW, Jesus gave out free wine. You know, a drug.
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madinpahuff
Domari Nolo
02:11 PM on 07/10/2011
I'm happily surprised by this post. Well done Sam. †
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11:49 AM on 07/10/2011
My local newspaper offers a section online that allows anyone to offer a topic of discussion which isn't necessarily a topic of current news. Someone posed the question "What is the one experience in life that has been most formative of who you are now?"

My answer was ingesting Sandoz psilcyn and reading The Doors of Perception back in 1970. The arc of my life was completely altered and I'm very grateful for the way in which it was.
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stuoverit
"What year did Jesus think it was?"-GC
12:32 PM on 07/11/2011
Seconded. Psilocybin rocked my brain in college followed by Doors of Perception/Heaven and Hell was an excellent, albeit cliche, alteration that I am thankful for every day.
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StephenJK
All your consciousness are belong to us
11:40 AM on 07/10/2011
What a great article. Sam, we may not agree on things metaphysical or hereafter, but, this we can wholeheartedly agree on; psychadelics are useful. As you outlined, there are many precautionary measures (set and setting) that one should excerise before "going off". And even before that, education. An experienced person is always helpful and I would argue, necessary.

Like Sam Harris, I've used a few times. I've experienced the blissful, childlike wonderment at the mundane and alternatively, the harrowing times. I've helped others get through really bad episodes and this points to what Sam referred to as compassion when we're "on". It's a matriarchical trait. The experience can help us figure things out that were previously unattainable. The "aha" moments are plentiful and beautiful.

Consiousness is the most beautiful thing in this universe and that's saying something considering how beautiful the physical universe is.

All your consciousness are belong to us!
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electrosef
Blue-green-purple Reality exposure
09:11 PM on 07/11/2011
Interesting... your subject noun, "consciousness" is singular, and your verb "are" is plural... so how many are there?
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StephenJK
All your consciousness are belong to us
05:46 AM on 07/12/2011
Ultimately, there is only one. As time goes on, the one becomes many. Like a tree with one root system but, infinite branches. We are somewhere in the middle of the tree. The source is unknown because we're not able to see past any of the other branches below us. But, we know something is down there. LOL But, my "micro bio" is a play on a poorly translated video game dialogue. One of the villainous characters in the game says "All your base are belong to us". Long story. Rather not go into what I think it means. You know with consciousness replacing "base".
10:22 AM on 07/10/2011
As a child (and from a remarkably early age), I experienced what I can only describe as altered states of consciousness as a result of deep meditation without being aware that that was what was happening. This resulted from what I now know to be labeled as "lucid dreaming," which was one of my favorite leisure activities for reasons I will not go into here. I could enter into my dream world at will (after some practice). Greater control gave greater satisfaction, and the ability evolved into something I can not adequately describe or explain, but it was very pleasant and soothing.

As a teen in the 70s, I experimented with drugs, preferring pot and psychedelics. I have now lost my earlier abilities, and despite no longer using drugs, seem unable to regain them. The natural "trip," taken solely by the power of my mind, was by far the superior experience....
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BornOKtheFirstTime
pedicabo ego vos et irrumabo
10:02 AM on 07/10/2011
I took LSD occasionally in my 20s, but have found that working with dreams on a regular basis using the techniques of archetypal/Jungian psychology takes you to a similar level of heightened awareness of the depths and possibilities of your own mind, beyond the confines of waking consciousness. These techniques teach you to stay in the dream and experience it rather than analyzing it away. The same unconscious content is accessed/released. As with psychedelics, however, serious in depth dream work can be quite destabilizing and can also unleash latent psychoses.
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Jim Sims
09:36 AM on 07/10/2011
The problem I have here is in the comparison to meditation etc. There are cases documented by ramdas where his guru takes large amounts of LSD at a time and has no affect on him at all. The author is somewhat vague and incorrect about his ideas concerning meditation and psychadelics
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StephenJK
All your consciousness are belong to us
11:27 AM on 07/10/2011
The guru might have achieved a state of awareness that could mask the effects. LSD definitely, without a doubt, like Sam Harris said, modulates neurochemistry. How those effects are realized in the individual vary wildly.
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Saijanai
Micro bio? We don't need no stinkin' micro bio...
11:16 PM on 07/10/2011
Different meditation techniques have different effects. One of the most common short-hand ways of describing enlightenment is that you are in a meditative state at all times. A somewhat more precise description is that pure consciousness "attained" during meditation, is never "lost" outside of meditation. The forest sages in the Upanishads didn't go into these elaborate details. They just talked about turya ("fourth" [state of consciousness] underling waking dreaming and sleeping) and some mention turyatita (quality or transcendence of the the fourth) where turya is noted as omnipresent.

An enlightened sage who took LSD, in theory, wouldn't notice any fundamental change in consciousness because the hallucinations of LSD are no more or less real than normal sensory perception to someone in this state. OR the actual physiological state of the nervous system would prevent the effects of LSD from happening at all due to some subtle changes in brain chemistry ("soma" is sometimes thought of as a neurotransmitter which supports enlightenment). Of course, it could be that both interpretations might apply: perhaps in the earliest stages it is only a psychological interpretation and in later stages the physiology supports the psychology of the interpretation -of course, transitional phases be mixtures between the two.

Studies on the physiology of turya, at least during Transcendental Meditation, have been published in various journals. A few studies on the physiology of people reporting turya 24 hours a day, 7 days a week, for years at a time, have also been published.
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Tyler James Lee
09:32 AM on 07/10/2011
When I came back to the world in '67 I was (though I didn't realize it and it wasn't overt) on a self-destructive path, and it's a wonder I didn't manage to kill myself. Fortunately, I found a "support group" of sorts and found LSD, which I used heavily for about two years. It saved my life, I believe...
But I learned (the hard way, of course) that these potent medicines are NOT for "trips", NOT recreational drugs. They have their own protocols and deserve respect. Not recommended for children...!
Genders
Love, Tolerance, Enlightenment
08:19 PM on 07/10/2011
Great comment. These are strong drugs. There are risks, but the rewards are usually well worth it. FF.
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jwashmon
Usually, everyone is right to a certain degree....
09:14 AM on 07/10/2011
I read once that every culture on the planet has mind altering experiences except the Eskimo and them only because there are none around. OOps we did bring them alcohol and tobacco, how good of us...
Anyone and eveyone should be able to enhance there experience in life with the use of drugs. It would be better if we (humans) where intelligent. Fear and ignorance has kept drugs legal/illegal in the wrong way for far too long. Too bad our political leaders are not up to the task of correcting this sad part of our lives. It is trully sad what we have done to our fellow man by making drugs illegal. Ask half or our prison population what they are in for, yes non-violent drug use.
Genders
Love, Tolerance, Enlightenment
08:21 PM on 07/10/2011
The Eskimo's use pain.
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senorlou
05:31 AM on 07/10/2011
We're only making plans for Nigel....