The message this sends to other Republicans in Congress (both House and Senate) is that this can happen to anyone. The fear this is going to create may become all-encompassing in the House, and possibly even the Senate (if Republicans win control of the chamber this November). The Tea Party sword hanging over their heads is now plain to see.
Whether a new immigration bill becomes law or not is now dependent on choices Boehner makes in the coming weeks. He has the ability of scuttling the entire process, should he choose, or to make immigration reform a reality. But no matter what he does, there are going to be some awfully upset Republicans after it is over.