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A government spokesman said said the blast caused a huge crater and authorities were investigating the exact “nature and motives” of the blast.
The explosion rocked a protest organized by Pakistan’s chemist and pharmaceuticals manufacturers.
The attacks occurred hours after militants killed two people in a Christian neighborhood in the same region.
The government has faced mounting pressure to pass the law against murders carried out by people professing to be acting in defense of the honor of their family.
Qandeel Baloch’s raunchy social media photos challenged social norms in Pakistan, a deeply conservative Muslim country.
Most were released and investigators are keeping 216 suspects in custody.
A faction of the Pakistani Taliban called Jamaat-ul-Ahrar claimed responsibility for the attack that killed at least 65 people.
Most of those killed are said to be women and children.
Watch this exclusive clip from a forthcoming documentary on Pakistan's unexpected musical revival.