From the German Chancellor Angela Merkel to the FLOTUS, we've chosen some heavy-hitters to make our list of the top 10 most-powerful women in the world.
Not everyone can say they are leading the bailouts of three major European economies or heading up U.S. foreign policy. See who rankes first in the video above.
Who do you think we should have included or left out?
BEFORE YOU GO
Here are Forbes' choices for the 10 most powerful women in media in 2011.