Piers Morgan Enrages Chelsea Handler (VIDEO)

WATCH: Piers Morgan Enrages Chelsea Handler

Piers Morgan appeared on Chelsea Handler's talk show Wednesday night and seemed to perturb the late night host.

When he sat down, Morgan wondered aloud about Handler's appearance. "You either had plastic surgery or make up, because you look really hot today," he said.

"You're so annoying! You're so obnoxious, you wonder why everybody hates you. I specifically covered up so you couldn't look at me and undress me with your molester eyes," Handler said.

Morgan appeared on Handler's show to celebrate the second anniversary of "Piers Morgan Tonight." Morgan touted his interviewing skills over Handler's and offered to help her improve her craft. "You can suck my ass," she replied. "I mean, really."

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