He will miss the remainder of the season.
Noel took to Twitter to thank those who have sent him their support.
Noel, the nation's leading shot blocker, landed awkwardly on his left leg and went down in obvious pain with about eight minutes remaining in the game. He had to be carried to the locker room by a few of his teammates.
"I'm physically sick right now for him," Kentucky coach John Calipari said after the game.
More from the Associated Press:
LEXINGTON, Ky. -- Kentucky freshman Nerlens Noel is out for the rest of the season with a torn ligament in his left knee.
Noel tore his ACL on Tuesday night when No. 25 Kentucky lost at Florida. An MRI on Wednesday revealed the injury.
The 6-foot-10 forward will have surgery in the two or three weeks. The projected recovery period is six to eight months.
Noel was hurt with 8 minutes left in the Wildcats' 69-52 loss to No. 7 Florida. He ran into the basket support after blocking a layup from behind. Noel landed awkwardly, dropped to the floor and started screaming while clutching his knee.