It's over for Angie Harmon and Jason Sehorn, her husband of 13 years.
The "Rizzoli & Isles" actress' rep issued a statement to People about the couple's separation on Sunday, saying, "For the sake of their children, they ask for respect and privacy as they navigate this time in their lives."
This was Harmon's first marriage and the second for Sehorn, who divorced first wife Whitney Casey after less than a year of marriage in 1999.
In 2011, Harmon opened up about the couple's marriage -- and the challenges of living apart when she's filming her show -- to Your Tango.
"You have to be really considerate of each other, really kind to each other. It's a lot of work, really," the former "Law & Order" star said.
She told Good Housekeeping that same year that communication is her most important marital rule.
"Communication is a huge, huge thing in marriage. And it doesn't matter if it's uncomfortable or brings up bad stuff," she said. "You really have to have the guts to talk to each other."