01/28/2015 08:16 am ET Updated Mar 30, 2015

Why Eradicating a Disease Is One Part Science, One Part Politics (VIDEO)

We've done it before. In 1980, the world wiped the devastating disease smallpox off the face of the earth -- making it the only human disease eradicated in history. So what does it take to destroy another human disease again?

Philanthropists Bill and Melinda Gates noted in their 2015 annual letter, which was published on Thursday, that the world is capable of eradicating more diseases in the next 15 years.

Check out the video above and/or read the transcript below for a two-minute explanation of just how that would work, made in a partnership between the Bill & Melinda Gates Foundation and The Huffington Post.

Do you think the world can stop another human disease by 2030? Let me know your thoughts in the comments.